(Q34981147)

5 August 2017

title

VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects (English)

1 reference

5 August 2017

1 reference

Blythe C Dillingham

4

0 references

Tony Huynh

Tony Huynh

5

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Christopher Heier

Christopher R Heier

1

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Jyoti K. Jaiswal

Jyoti K Jaiswal

19

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Kanneboyina Nagaraju

24

Kanneboyina Nagaraju

1 reference

5 August 2017

Heather Gordish-Dressman

18

Heather Gordish-Dressman

1 reference

5 August 2017

22

Eric P Hoffman

1 reference

5 August 2017

Jesse M Damsker

2

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5 August 2017

Qing Yu

3

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5 August 2017

Jack H Van der Meulen

6

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5 August 2017

Arpana Sali

7

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5 August 2017

Brittany K Miller

8

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5 August 2017

Aditi Phadke

9

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5 August 2017

Luana Scheffer

10

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5 August 2017

James Quinn

11

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5 August 2017

Kathleen Tatem

12

1 reference

5 August 2017

Sarah Jordan

13

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5 August 2017

Sherry Dadgar

14

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5 August 2017

Olga C Rodriguez

15

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5 August 2017

Chris Albanese

16

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5 August 2017

Michael Calhoun

17

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5 August 2017

Edward M Connor

20

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5 August 2017

John M McCall

21

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5 August 2017

Erica K M Reeves

23

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5 August 2017

publication date

9 September 2013

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5 August 2017

published in

EMBO Molecular Medicine

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5 August 2017

volume

5

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5 August 2017

issue

10

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5 August 2017

page(s)

1569-1585

1 reference

describes a project that uses

5 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3799580/fullTextXML

inferred from PubMed Central ID database lookup

cites work

VBP15: preclinical characterization of a novel anti-inflammatory delta 9,11 steroid

1 reference

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A call for transparent reporting to optimize the predictive value of preclinical research

8 July 2018

1 reference

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Use of quantitative membrane proteomics identifies a novel role of mitochondria in healing injured muscles.

8 July 2018

1 reference

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Δ-9,11 modification of glucocorticoids dissociates nuclear factor-κB inhibitory efficacy from glucocorticoid response element-associated side effects.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Glucocorticoid-treated mice are an inappropriate positive control for long-term preclinical studies in the mdx mouse

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Hsp72 preserves muscle function and slows progression of severe muscular dystrophy

8 July 2018

1 reference

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Promotion of plasma membrane repair by vitamin E.

8 July 2018

1 reference

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Enhancing translation: guidelines for standard pre-clinical experiments in mdx mice

8 July 2018

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Restoring dystrophin expression in duchenne muscular dystrophy muscle progress in exon skipping and stop codon read through

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Improvement of cardiac contractile function by peptide-based inhibition of NF-κB in the utrophin/dystrophin-deficient murine model of muscular dystrophy

8 July 2018

1 reference

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Membrane sealant Poloxamer P188 protects against isoproterenol induced cardiomyopathy in dystrophin deficient mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Peptide-based inhibition of NF-κB rescues diaphragm muscle contractile dysfunction in a murine model of Duchenne muscular dystrophy.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

In-frame dystrophin following exon 51-skipping improves muscle pathology and function in the exon 52-deficient mdx mouse

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Non-invasive optical imaging of muscle pathology in mdx mice using cathepsin caged near-infrared imaging

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Chronic administration of membrane sealant prevents severe cardiac injury and ventricular dilatation in dystrophic dogs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Combination of myostatin pathway interference and dystrophin rescue enhances tetanic and specific force in dystrophic mdx mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Dysferlin deficiency and the development of cardiomyopathy in a mouse model of limb-girdle muscular dystrophy 2B.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Prevention of dystrophic pathology in severely affected dystrophin/utrophin-deficient mice by morpholino-oligomer-mediated exon-skipping

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

A robust in vitro screening assay to identify NF-kappaB inhibitors for inflammatory muscle diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Developing standard procedures for murine and canine efficacy studies of DMD therapeutics: report of two expert workshops on "Pre-clinical testing for Duchenne dystrophy": Washington DC, October 27th-28th 2007 and Zürich, June 30th-July 1st 2008.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Preclinical drug trials in the mdx mouse: assessment of reliable and sensitive outcome measures

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Mammalian animal models for Duchenne muscular dystrophy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Hedgehog signaling has a protective effect in glucocorticoid-induced mouse neonatal brain injury through an 11betaHSD2-dependent mechanism.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Absence of alpha 7 integrin in dystrophin-deficient mice causes a myopathy similar to Duchenne muscular dystrophy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Brain response to injury and neurodegeneration: endogenous neuroprotective signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

IKKbeta/NF-kappaB activation causes severe muscle wasting in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Defective membrane repair in dysferlin-deficient muscular dystrophy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Glucocorticoids stimulate human sgk1 gene expression by activation of a GRE in its 5'-flanking region

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

A chronic inflammatory response dominates the skeletal muscle molecular signature in dystrophin-deficient mdx mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Lazaroids: efficacy and mechanism of action of the 21-aminosteroids in neuroprotection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Role for alpha-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Equivalent doses and relative drug potencies for non-genomic glucocorticoid effects: a novel glucocorticoid hierarchy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Severe cardiomyopathy in mice lacking dystrophin and MyoD

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

DNA binding of the glucocorticoid receptor is not essential for survival

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Mutation/polymorphism scanning of glucose-6-phosphatase gene promoter in noninsulin-dependent diabetes mellitus patients

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Subtle neuromuscular defects in utrophin-deficient mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Contractile properties of skeletal muscles from young, adult and aged mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Isolation and characterization of a mouse L cell variant deficient in glucocorticoid receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Short term linear growth in asthmatic children during treatment with prednisolone

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Transcription factor interactions: selectors of positive or negative regulation from a single DNA element.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Interaction of the glucocorticoid receptor DNA-binding domain with DNA as a dimer is mediated by a short segment of five amino acids

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Demonstration of cathepsins B, H and L in xenografts of normal and Duchenne-muscular-dystrophy muscles transplanted into nude mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Muscular dystrophy and activation of proteinases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799580

Glucocorticoid effects on statural growth.

8 July 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201302621

Contrasting effects of steroids and angiotensin-converting-enzyme inhibitors in a mouse model of dystrophin-deficient cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201302621

Ventilator-induced cell wounding and repair in the intact lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201302621

Anti-TNFalpha (Remicade) therapy protects dystrophic skeletal muscle from necrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201302621

Prednisone therapy in Becker's muscular dystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201302621

Increased vulnerability to kainate-induced seizures in utrophin-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201302621

Disodium cromoglycate protects dystrophin-deficient muscle fibers from leakiness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201302621

Dissection of temporal gene expression signatures of affected and spared muscle groups in dystrophin-deficient (mdx) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201302621

Consequence of parvalbumin deficiency in the mdx mouse: histological, biochemical and mechanical phenotype of a new double mutant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201302621

Dexamethasone blocks the rapid biological effects of 17beta-estradiol in the rat uterus without antagonizing its global genomic actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201302621

In vitro evaluation of the antioxidant activity and biomembrane interaction of the lazaroid U-74389G.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201302621

Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201302621

Distinct domains of the RelA NF-kappaB subunit are required for negative cross-talk and direct interaction with the glucocorticoid receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201302621

Dystrophic heart failure blocked by membrane sealant poloxamer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201302621

CLEFT PALATE IN THE MOUSE: A TERATOGENIC INDEX OF GLUCOCORTICOID POTENCY

21 January 2018

1 reference

12 December 2020

Muscle calcium and magnesium content in Duchenne muscular dystrophy

1 reference

12 December 2020

Early onset of inflammation and later involvement of TGFbeta in Duchenne muscular dystrophy

1 reference

12 December 2020

A molecular bandage for diseased muscle

1 reference

12 December 2020

Therapeutic implications of non-genomic glucocorticoid activity

1 reference

12 December 2020

Patients with a Non-dysferlin Miyoshi Myopathy have a Novel Membrane Repair Defect

1 reference

12 December 2020

Growing muscle has different sarcolemmal properties from adult muscle: a proposal with scientific and clinical implications: reasons to reassess skeletal muscle molecular dynamics, cellular responses and suitability of experimental models of muscle

1 reference

12 December 2020

Steroid-induced perturbations of membranes and its relevance to sperm acrosome reaction

1 reference

12 December 2020

Duchenne dystrophy: randomized, controlled trial of prednisone (18 months) and azathioprine (12 months)

1 reference

12 December 2020

Mononuclear cell analysis of muscle biopsies in prednisone- and azathioprine-treated Duchenne muscular dystrophy

1 reference

12 December 2020

Cromolyn increases strength in exercised mdx mice

1 reference

12 December 2020

The effect of alternate-day low dose prednisolone on bone age in children with steroid dependent nephrotic syndrome

1 reference

12 December 2020

Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy

1 reference

12 December 2020

Muscle cells from mdx mice have an increased susceptibility to oxidative stress

1 reference

12 December 2020

Evidence of oxidative stress in mdx mouse muscle: studies of the pre-necrotic state

1 reference

12 December 2020

New developments in the pathogenesis and treatment of steroid-induced osteoporosis

1 reference

12 December 2020

Identifiers

DOI

10.1002/EMMM.201302621

1 reference

5 August 2017

1 reference

5 August 2017

1 reference