(Q34981331)

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Anti-inflammatory and immunomodulating properties of statins. An additional tool for the therapeutic approach of systemic autoimmune diseases?

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

1 reference

Europe PubMed Central

Anti-inflammatory and immunomodulating properties of statins. An additional tool for the therapeutic approach of systemic autoimmune diseases? (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Pier Luigi Meroni

1

object named as

Pier Luigi Meroni

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

author name string

Cristina Luzzana

2

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Donatella Ventura

3

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

publication date

1 December 2002

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Clinical Reviews in Allergy & Immunology

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

23

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

263-277

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

In vivo anti-inflammatory effect of statins is mediated by nonsterol mevalonate products

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of Rho GTPases in the transcriptional inhibition of preproendothelin-1 gene expression by simvastatin in vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are there potential non-lipid-lowering uses of statins?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of pravastatin on acute rejection after kidney transplantation--a pilot study

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of C-reactive protein and risk of coronary events in stable and unstable angina. European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Risk factors for coronary artery disease in patients with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemostatic factors and cardiovascular disease in active rheumatoid arthritis: an 8 year followup study

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of atorvastatin on plasminogen activator inhibitor type-1 synthesis in human monocytes/macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vastatins Inhibit Tissue Factor in Cultured Human Macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta 2-glycoprotein I-anti-beta 2-glycoprotein I interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibitory effects of pravastatin on natural killer cell activity in vivo and on cytotoxic T lymphocyte activity in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipids, cardiovascular disease and atherosclerosis in systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accelerated atheroma, antiphospholipid antibodies, and the antiphospholipid syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic lupus erythematosus: a model for atherogenesis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of simvastatin on ejection fraction in cardiac transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simvastatin modulates cytokine-mediated endothelial cell adhesion molecule induction: involvement of an inhibitory G protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of statin therapy on C-reactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relative role of low-density lipoprotein cholesterol and high-density lipoprotein cholesterol in coronary artery disease: evidence from large-scale statin and fibrate trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extent of inflammation predicts cardiovascular disease and overall mortality in seropositive rheumatoid arthritis. A retrospective cohort study from disease onset

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of functional CD40 by vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Classification of anti-endothelial cell antibodies into antibodies against microvascular and macrovascular endothelial cells: the pathogenic and diagnostic implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of statins on vascular wall: vasomotor function, inflammation, and plaque stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of statins on C-reactive protein in patients with coronary artery disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of interferon-gamma-mediated microvascular endothelial cell major histocompatibility complex class II gene activation by HMG-CoA reductase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-function studies on beta 2-glycoprotein I.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of endothelial cell migration by cerivastatin, an HMG-CoA reductase inhibitor: contribution to its anti-angiogenic effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HMG-CoA reductase inhibitors reduce vascular monocyte chemotactic protein-1 expression in early lesions from hypercholesterolemic swine independently of their effect on plasma cholesterol levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Approaches to rheumatoid arthritis in 2000.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of autoantibody-mediated thrombosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluvastatin increases prostacyclin and decreases endothelin production by human umbilical vein endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesion of activated platelets to endothelial cells: evidence for a GPIIbIIIa-dependent bridging mechanism and novel roles for endothelial intercellular adhesion molecule 1 (ICAM-1), alphavbeta3 integrin, and GPIbalpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pleiotropic effects of statins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial cells in physiology and in the pathophysiology of vascular disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current perspectives on statins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compensatory enlargement of human atherosclerotic coronary arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epitope studies with anti-beta 2-glycoprotein I antibodies from autoantibody and immunized sources

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statins prevent endothelial cell activation induced by antiphospholipid (anti-beta2-glycoprotein I) antibodies: effect on the proadhesive and proinflammatory phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of monocyte chemotactic protein-1 synthesis by statins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus: comparison with the Framingham Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of preexisting statin use on adhesion molecule expression in patients presenting with acute coronary syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new HMG-CoA reductase inhibitor, rosuvastatin, exerts anti-inflammatory effects on the microvascular endothelium: the role of mevalonic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibrinogen and risk of cardiovascular disease. The Framingham Study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of fluvastatin, an HMG-CoA reductase inhibitor, on the expression of adhesion molecules on human monocyte cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statins as a newly recognized type of immunomodulator

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HMG CoA reductase inhibitors affect the fibrinolytic system of human vascular cells in vitro: a comparative study using different statins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of proinflammatory cytokine production by pravastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of lymphoid cell function in vitro by inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by lovastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-lipid-related effects of statins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Joint swelling as a predictor of death from cardiovascular disease in a population study of Pima Indians

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of different inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, pravastatin sodium and simvastatin, on sterol synthesis and immunological functions in human lymphocytes in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atherosclerosis — An Inflammatory Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunology of the antiphospholipid antibody syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: reduction of MRNA levels for interleukin-1beta, interleukin-6, cyclooxygenase-2, and p22phox by regulation of peroxisome proliferator-activated receptor alpha (PPARalpha) in pri

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of small G proteins of the rho family by statins or clostridium difficile toxin B enhances cytokine-mediated induction of NO synthase II.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of hydroxymethyl glutaryl coenzyme a reductase inhibitor therapy on high sensitive C-reactive protein levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A tale of two diseases: atherosclerosis and rheumatoid arthritis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complement-endothelial cell interactions: pathophysiological implications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydroxymethylglutaryl coenzyme A reductase inhibitors modify the inflammatory response of human macrophages and endothelial cells infected with Chlamydia pneumoniae

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Premature atherosclerosis in systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes: a role for CD40 signaling in plaque rupture?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term effects of pravastatin on plasma concentration of C-reactive protein. The Cholesterol and Recurrent Events (CARE) Investigators

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Premature morbidity from cardiovascular and cerebrovascular diseases in women with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluvastatin reduces soluble P-selectin and ICAM-1 levels in hypercholesterolemic patients: role of nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further evidence for direct vascular actions of statins: effect on endothelial nitric oxide synthase and adhesion molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenic mechanisms mediating antiphospholipid syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levels of soluble cell adhesion molecules in patients with dyslipidemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simvastatin attenuates vascular hypercoagulability in cardiac transplant recipients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of pravastatin on outcomes after cardiac transplantation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adoptive transfer of beta(2)-glycoprotein I-reactive lymphocytes enhances early atherosclerosis in LDL receptor-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligation of CD40 activates interleukin 1beta-converting enzyme (caspase-1) activity in vascular smooth muscle and endothelial cells and promotes elaboration of active interleukin 1beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptors in inflammation control

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-inflammatory effects of simvastatin in subjects with hypercholesterolemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12402412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1385/CRIAI:23:3:263

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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