(Q34984370)

5 August 2017

title

DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia (English)

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5 August 2017

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6

Peter B Dervan

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5 August 2017

2

Christian Melander

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5 August 2017

Ryan Burnett

1

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5 August 2017

James W Puckett

3

1 reference

5 August 2017

Leslie S Son

4

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5 August 2017

Robert D Wells

5

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5 August 2017

Joel M Gottesfeld

7

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5 August 2017

language of work or name

English

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publication date

20 July 2006

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Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

published in

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5 August 2017

volume

103

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5 August 2017

issue

31

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5 August 2017

page(s)

11497-11502

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describes a project that uses

5 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1544198/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Gene expression profiling in frataxin deficient mice: microarray evidence for significant expression changes without detectable neurodegeneration

8 July 2018

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Defining the sequence-recognition profile of DNA-binding molecules

8 July 2018

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Frataxin deficiency alters heme pathway transcripts and decreases mitochondrial heme metabolites in mammalian cells.

8 July 2018

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Arresting cancer proliferation by small-molecule gene regulation

8 July 2018

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Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates

8 July 2018

1 reference

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Sequence-specific gene silencing in mammalian cells by alkylating pyrrole-imidazole polyamides

8 July 2018

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Accessibility of Nuclear Chromatin by DNA Binding Polyamides

8 July 2018

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Nuclear localization of pyrrole–imidazole polyamide–fluorescein conjugates in cell culture

8 July 2018

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Recognition of the DNA minor groove by pyrrole-imidazole polyamides

8 July 2018

1 reference

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A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

8 July 2018

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8 July 2018

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Expression profiling in multistage hepatocarcinogenesis: identification of HSP70 as a molecular marker of early hepatocellular carcinoma.

8 July 2018

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Structure of a beta-alanine-linked polyamide bound to a full helical turn of purine tract DNA in the 1:1 motif

8 July 2018

1 reference

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Footprinting methods for analysis of pyrrole-imidazole polyamide/DNA complexes

8 July 2018

1 reference

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Toward rules for 1:1 polyamide:DNA recognition

8 July 2018

1 reference

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Alleviating transcript insufficiency caused by Friedreich's ataxia triplet repeats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544198

The GAA*TTC triplet repeat expanded in Friedreich's ataxia impedes transcription elongation by T7 RNA polymerase in a length and supercoil dependent manner

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544198

The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544198

Recognition of DNA by designed ligands at subnanomolar concentrations

8 July 2018

1 reference

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Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

8 July 2018

1 reference

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Inhibitory effects of expanded GAA.TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo

8 July 2018

1 reference

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Sticky DNA: self-association properties of long GAA.TTC repeats in R.R.Y triplex structures from Friedreich's ataxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604939103

Sticky DNA: effect of the polypurine.polypyrimidine sequence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604939103

Sticky DNA formation in vivo alters the plasmid dimer/monomer ratio

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604939103

Chromatin opening of DNA satellites by targeted sequence-specific drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604939103

Specific gain- and loss-of-function phenotypes induced by satellite-specific DNA-binding drugs fed to Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604939103

Expansion of GAA triplet repeats in the human genome: unique origin of the FRDA mutation at the center of an Alu.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604939103

DNA triplet repeats mediate heterochromatin-protein-1-sensitive variegated gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604939103

21 January 2018

1 reference

12 December 2020

Structure-dependent recombination hot spot activity of GAA.TTC sequences from intron 1 of the Friedreich's ataxia gene

1 reference

12 December 2020

Sticky DNA, a long GAA.GAA.TTC triplex that is formed intramolecularly, in the sequence of intron 1 of the frataxin gene

1 reference

12 December 2020

Sticky DNA, a self-associated complex formed at long GAA*TTC repeats in intron 1 of the frataxin gene, inhibits transcription

1 reference

12 December 2020

Sticky DNA: in vivo formation in E. coli and in vitro association of long GAA*TTC tracts to generate two independent supercoiled domains

1 reference

12 December 2020

Blocking transcription through a nucleosome with synthetic DNA ligands

1 reference

12 December 2020

Phenotypic variability in Friedreich ataxia: role of the associated GAA triplet repeat expansion

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0604939103

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference