(Q34987265)

5 August 2017

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title

Present status on the genetic studies of asthma (English)

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5 August 2017

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2

Carole Ober

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5 August 2017

Sabine Hoffjan

1

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5 August 2017

publication date

1 December 2002

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Current Opinion in Immunology

5 August 2017

published in

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5 August 2017

volume

14

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5 August 2017

issue

6

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5 August 2017

page(s)

709-717

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International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods

5 August 2017

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Environmental factors as a cause for the increase in allergic disease

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7 January 2021

The alliance of genes and environment in asthma and allergy

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7 January 2021

A genome-wide search for quantitative trait loci underlying asthma

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7 January 2021

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7 January 2021

Genome-wide linkage analyses of total serum IgE using variance components analysis in asthmatic families

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7 January 2021

A Genome-wide Search for Linkage to Asthma22See the Appendix

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7 January 2021

Genome Screen for Asthma and Related Phenotypes in the French EGEA Study

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7 January 2021

Major genes regulating total serum immunoglobulin E levels in families with asthma

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7 January 2021

Genome-wide search for atopy susceptibility genes in Dutch families with asthma

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7 January 2021

Significant evidence for linkage of mite-sensitive childhood asthma to chromosome 5q31-q33 near the interleukin 12 B locus by a genome-wide search in Japanese families

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7 January 2021

A genome-wide linkage analysis of orchard grass-sensitive childhood seasonal allergic rhinitis in Japanese families

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7 January 2021

A genomewide search for quantitative-trait loci underlying asthma

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7 January 2021

A susceptibility locus for asthma-related traits on chromosome 7 revealed by genome-wide scan in a founder population

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7 January 2021

Allergic rhinitis--a total genome-scan for susceptibility genes suggests a locus on chromosome 4q24-q27

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7 January 2021

An Internet linkage and mutation database for the complex phenotype asthma

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7 January 2021

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

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7 January 2021

Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice

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7 January 2021

Quantitative trait loci controlling allergen-induced airway hyperresponsiveness in inbred mice

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7 January 2021

A genome-wide screen for asthma-associated quantitative trait loci in a mouse model of allergic asthma

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7 January 2021

Current concepts on the genetics of asthma

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7 January 2021

Atopy and asthma genes--where do we stand?

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7 January 2021

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7 January 2021

Contributing factors to the pathobiology. The genetics of asthma

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7 January 2021

Interleukin-13: central mediator of allergic asthma

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7 January 2021

The relative contribution of IL-4 and IL-13 to human IgE synthesis induced by activated CD4+ or CD8+ T cells

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7 January 2021

Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations

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7 January 2021

Evidence for a locus regulating total serum IgE levels mapping to chromosome 5

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7 January 2021

Linkage and allelic association of chromosome 5 cytokine cluster genetic markers with atopy and asthma associated traits

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7 January 2021

Factor analysis of asthma and atopy traits shows 2 major components, one of which is linked to markers on chromosome 5q.

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7 January 2021

Functional screening of an asthma QTL in YAC transgenic mice.

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7 January 2021

Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy

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7 January 2021

Atopy and asthma: genetic variants of IL-4 and IL-13 signalling

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7 January 2021

Association between a sequence variant in the IL-4 gene promoter and FEV(1) in asthma

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7 January 2021

Polymorphisms in the IL4, IL4RA, and FCERIB genes and asthma severity

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7 January 2021

Childhood atopic asthma: positive association with a polymorphism of IL-4 receptor alpha gene but not with that of IL-4 promoter or Fc epsilon receptor I beta gene

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7 January 2021

Interleukin-4 gene promoter polymorphism [C590T] and asthma in Kuwaiti Arabs

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7 January 2021

Polymorphisms of the IL-4, TNF-alpha, and Fcepsilon RIbeta genes and the risk of allergic disorders in at-risk infants

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7 January 2021

The -590C/T and -34C/T interleukin-4 promoter polymorphisms are not associated with atopic eczema in childhood

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7 January 2021

Association between a C+33T polymorphism in the IL-4 promoter region and total serum IgE levels

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7 January 2021

Indication of linkage of serum IgE levels to the interleukin-4 gene and exclusion of the contribution of the (-590 C to T) interleukin-4 promoter polymorphism to IgE variation

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7 January 2021

An IL-13 promoter polymorphism associated with increased risk of allergic asthma

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7 January 2021

Identification and association of polymorphisms in the interleukin-13 gene with asthma and atopy in a Dutch population

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7 January 2021

Genetic variants of IL-13 signalling and human asthma and atopy

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7 January 2021

A cluster of seven tightly linked polymorphisms in the IL-13 gene is associated with total serum IgE levels in three populations of white children

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7 January 2021

An IL13 coding region variant is associated with a high total serum IgE level and atopic dermatitis in the German multicenter atopy study (MAS-90)

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7 January 2021

A polymorphism in the coding region of interleukin-13 gene is associated with atopy but not asthma in Chinese children

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7 January 2021

Lack of association between a polymorphism in the interleukin-13 gene and total serum immunoglobulin E level among nuclear families in Costa Rica

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7 January 2021

Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence Comparisons

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7 January 2021

Deletion of a coordinate regulator of type 2 cytokine expression in mice

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7 January 2021

Haplotypes of the 5' region of the IL-4 gene and SNPs in the intergene sequence between the IL-4 and IL-13 genes are associated with atopic asthma

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7 January 2021

Common polymorphisms in the coding part of the IL4-receptor gene

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7 January 2021

The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor

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7 January 2021

Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations

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7 January 2021

A population genetics study of single nucleotide polymorphisms in the interleukin 4 receptor alpha (IL4RA) gene

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7 January 2021

Atopy and the human IL-4 receptor alpha chain

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7 January 2021

Interleukin 4 receptor alpha chain polymorphism Gln551Arg is associated with adult atopic dermatitis in Japan

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7 January 2021

Lack of association between atopic eczema and the genetic variants of interleukin-4 and the interleukin-4 receptor alpha chain gene: heterogeneity of genetic backgrounds on immunoglobulin E production in atopic eczema patients

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7 January 2021

No linkage and association of atopy to chromosome 16 including the interleukin-4 receptor gene

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7 January 2021

The interleukin-4 receptor variant Q576R in hyper-IgE syndrome

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7 January 2021

No linkage or association of the IL-4Ralpha gene Q576R mutation with atopic asthma in Italian families

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7 January 2021

The polymorphisms S503P and Q576R in the interleukin-4 receptor alpha gene are associated with atopy and influence the signal transduction

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7 January 2021

Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma

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7 January 2021

A novel polymorphism in the 5' promoter region of the human interleukin-4 receptor alpha-chain gene is associated with decreased soluble interleukin-4 receptor protein levels

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7 January 2021

Enhancement of human IL-4 activity by soluble IL-4 receptors in vitro

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7 January 2021

Efficacy of soluble IL-4 receptor for the treatment of adults with asthma

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7 January 2021

Novel polymorphism in the coding region of the IL-13 receptor alpha' gene: association study with atopic asthma in the Japanese population

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7 January 2021

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

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7 January 2021

IL-13-induced airway hyperreactivity during respiratory syncytial virus infection is STAT6 dependent

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7 January 2021

Variants of STAT6 (signal transducer and activator of transcription 6) in atopic asthma

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7 January 2021

Novel dinucleotide repeat polymorphism in the first exon of the STAT-6 gene is associated with allergic diseases

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7 January 2021

STAT6 as an asthma candidate gene: polymorphism-screening, association and haplotype analysis in a Caucasian sib-pair study.

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7 January 2021

Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness

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7 January 2021

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

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7 January 2021

A major susceptibility gene for asthma maps to chromosome 14q24

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7 January 2021

10.1016/S0952-7915(02)00393-X

Identifiers

DOI

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5 August 2017

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