(Q34987317)

5 August 2017

1 reference

title

Genetics of autoimmune diseases in humans and in animal models (English)

1 reference

5 August 2017

Grant Morahan

1

1 reference

PubMed ID

12413533

5 August 2017

Laurence Morel

series ordinal

2

1 reference

PubMed ID

12413533

5 August 2017

language of work or name

1 reference

1 December 2002

1 reference

Current Opinion in Immunology

5 August 2017

1 reference

5 August 2017

14

1 reference

5 August 2017

6

1 reference

5 August 2017

803-811

1 reference

Genomewide scans of complex human diseases: true linkage is hard to find

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

A genomewide scan for type 1-diabetes susceptibility in Scandinavian families: identification of new loci with evidence of interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Understanding autoimmune diabetes: insights from mouse models.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Complete primary structure, chromosomal localisation, and definition of polymorphisms of the gene encoding the human interleukin-12 p40 subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

IL-12p40 is associated with type 1 diabetes in Caucasian-American families.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Interleukin-12p40 genotype plays a role in the susceptibility to multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

A promoter polymorphism in the gene encoding interleukin-12 p40 (IL12B) is associated with mortality from cerebral malaria and with reduced nitric oxide production

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Polymorphisms in cytokine genes define subpopulations of HIV-1 patients who experienced immune restoration diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Polymorphisms in the Il12b gene affect structure and expression of IL-12 in NOD and other autoimmune-prone mouse strains.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

The insulin gene in diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: the mechanism by which the IDDM2 locus may predispose to diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

CTLA-4 in autoimmune diseases--a general susceptibility gene to autoimmunity?

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Dinucleotide repeat expansion in the CTLA-4 gene leads to T cell hyper-reactivity via the CD28 pathway in myasthenia gravis

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Technical note: linkage disequilibrium and disease-associated CTLA4 gene polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

The genetics of complex autoimmune diseases: non-MHC susceptibility genes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

A gene telomeric of the HLA class I region is involved in predisposition to both type 1 diabetes and coeliac disease

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Association analysis using refined microsatellite markers localizes a susceptibility locus for psoriasis vulgaris within a 111 kb segment telomeric to the HLA-C gene

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Localization of central MHC genes influencing type I diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Conditional linkage disequilibrium analysis of a complex disease superlocus, IDDM1 in the HLA region, reveals the presence of independent modifying gene effects influencing the type 1 diabetes risk encoded by the major HLA-DQB1, -DRB1 disease loci

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

An interval tightly linked to but distinct from the H2 complex controls both overt diabetes (Idd16) and chronic experimental autoimmune thyroiditis (Ceat1) in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Markers on distal chromosome 2q linked to insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Suggestive Evidence for Association of Human Chromosome 18q12-q21 and Its Orthologue on Rat and Mouse Chromosome 18 With Several Autoimmune Diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Genetic control of collagen-induced arthritis in a cross with NOD and C57BL/10 mice is dependent on gene regions encoding complement factor 5 and FcgammaRIIb and is not associated with loci controlling diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

High resolution linkage and association mapping identifies a novel rheumatoid arthritis susceptibility locus homologous to one linked to two rat models of inflammatory arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Genetic modifiers of systemic lupus erythematosus in FcgammaRIIB(-/-) mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Mapping by Genetic Interaction: High-Resolution Congenic Mapping of the Type 1 Diabetes Loci Idd10 and Idd18 in the NOD Mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Transgenic rescue implicates beta2-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Epistatic modifiers of autoimmunity in a murine model of lupus nephritis

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

NKT cells: facts, functions and fallacies.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

The role of complement in inflammation and adaptive immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Autoimmunity provoked by infection: how good is the case for T cell epitope mimicry?

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

The CD2-subset of the Ig superfamily of cell surface molecules: receptor-ligand pairs expressed by NK cells and other immune cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

The diabetes-prone BB rat carries a frameshift mutation in Ian4, a positional candidate of Iddm1

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Delineating the genetic basis of systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Mutation of E2F2 in Mice Causes Enhanced T Lymphocyte Proliferation, Leading to the Development of Autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Mice lacking the p53-effector gene Gadd45a develop a lupus-like syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Role of cyclin kinase inhibitor p21 in systemic autoimmunity.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Mice with targeted gene disruptions or gene insertions for diabetes research: problems, pitfalls, and potential solutions

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Transgenic models of autoimmune disease

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Genome-wide ENU mutagenesis to reveal immune regulators

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Gene expression profiling of the nervous system in murine experimental autoimmune encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Project normal: defining normal variance in mouse gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

Association of IL12B promoter polymorphism with severity of atopic and non-atopic asthma in children.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900401-6

7 January 2021

10.1016/S0952-7915(02)00401-6

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12413533