(Q34987783)

5 August 2017

title

Arimetamycin A: improving clinically relevant families of natural products through sequence-guided screening of soil metagenomes (English)

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5 August 2017

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2

Sean F Brady

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5 August 2017

Hahk-Soo Kang

1

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5 August 2017

language of work or name

English

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publication date

3 September 2013

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full work available at URL

5 August 2017

https://europepmc.org/articles/pmc3878715?pdf=render

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19 March 2024

https://api.unpaywall.org/v2/10.1002/anie.201305109?email=unpaywall_01@example.com

published in

Angewandte Chemie International Edition

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volume

52

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5 August 2017

issue

42

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5 August 2017

page(s)

11063-11067

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https://api.unpaywall.org/v2/10.1002/anie.201305109?email=unpaywall_01@example.com

5 August 2017

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19 March 2024

access restriction status

open access

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inferred from online access status

cites work

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An environmental DNA-derived type II polyketide biosynthetic pathway encodes the biosynthesis of the pentacyclic polyketide erdacin

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Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin

8 July 2018

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Discovery of a daunorubicin analogue that exhibits potent antitumor activity and overcomes P-gp-mediated drug resistance

8 July 2018

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High molecular weight DNA recovery from soils prerequisite for biotechnological metagenomic library construction

8 July 2018

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The role of the novel Fem protein VanK in vancomycin resistance in Streptomyces coelicolor

8 July 2018

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Phylogenetic analysis of polyketide synthase I domains from soil metagenomic libraries allows selection of promising clones

8 July 2018

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Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity

8 July 2018

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The Uncultured Microbial Majority

8 July 2018

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Recombinant environmental libraries provide access to microbial diversity for drug discovery from natural products

8 July 2018

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Microbial diversity and function in soil: from genes to ecosystems

8 July 2018

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The entire nogalamycin biosynthetic gene cluster of Streptomyces nogalater: characterization of a 20-kb DNA region and generation of hybrid structures

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Role of the sugar moiety in the pharmacological activity of anthracyclines: development of a novel series of disaccharide analogs.

8 July 2018

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Strategies for discovering drugs from previously unexplored natural products

8 July 2018

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Molecular biological access to the chemistry of unknown soil microbes: a new frontier for natural products

8 July 2018

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Evolutionary origins of multidrug and drug-specific efflux pumps in bacteria

8 July 2018

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A study of iterative type II polyketide synthases, using bacterial genes cloned from soil DNA: a means to access and use genes from uncultured microorganisms

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3878715

DNA recovery from soils of diverse composition.

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3878715

Influence of structural modifications at the 3' and 4' positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome multidrug resistance.

8 July 2018

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Characterization of the Streptomyces peucetius ATCC 29050 genes encoding doxorubicin polyketide synthase

8 July 2018

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Anthracycline analogs: the past, present, and future

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3878715

Multidrug resistance in a human small cell lung cancer cell line selected in adriamycin.

8 July 2018

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Moving posttranslational modifications forward to biosynthesize the glycosylated thiopeptide nocathiacin I in Nocardia sp. ATCC202099.

8 July 2018

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Crossref

https://api.crossref.org/works/10.1002%2FANIE.201305109

Heterologous production of polyketides in bacteria

21 January 2018

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12 December 2020

Generation of hybrid elloramycin analogs by combinatorial biosynthesis using genes from anthracycline-type and macrolide biosynthetic pathways

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12 December 2020

Triggering cryptic natural product biosynthesis in microorganisms

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12 December 2020

Decreased resistance to N,N-dimethylated anthracyclines in multidrug-resistant Friend erythroleukemia cells

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12 December 2020

Structure-activity relationships of anthracyclines relative to cytotoxicity and effects on macromolecular synthesis in L1210 leukemia cells

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Die biosynthetische Grundlage der Polyketid-Vielfalt

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9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201305109

Structural elucidation of lemonomycin, a potent antibiotic from Streptomyces candidus

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9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201305109

Identifiers

DOI

10.1002/ANIE.201305109

1 reference

5 August 2017

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5 August 2017

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