(Q34989475)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21072045%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

A genome-wide approach identifies that the aspartate metabolism pathway contributes to asparaginase sensitivity (English)

1 reference

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16 January 2020

4

1 reference

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16 January 2020

author name string

S-H Chen

1

1 reference

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16 January 2020

W Yang

2

1 reference

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16 January 2020

Y Fan

3

1 reference

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16 January 2020

K R Crews

5

1 reference

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16 January 2020

J J Yang

6

1 reference

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16 January 2020

S W Paugh

7

1 reference

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16 January 2020

C-H Pui

8

1 reference

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16 January 2020

W E Evans

9

1 reference

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16 January 2020

M V Relling

10

1 reference

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16 January 2020

publication date

12 November 2010

1 reference

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16 January 2020

1 reference

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16 January 2020

volume

25

1 reference

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16 January 2020

issue

1

1 reference

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16 January 2020

page(s)

66-74

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https://scigraph.springernature.com/pub.10.1038/leu.2010.256

16 January 2020

exact match

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Pharmacogenomic discovery using cell-based models

8 July 2018

1 reference

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Treating childhood acute lymphoblastic leukemia without cranial irradiation

8 July 2018

1 reference

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Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity.

8 July 2018

1 reference

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Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia

8 July 2018

1 reference

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Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines

8 July 2018

1 reference

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Mutations and polymorphisms in the human argininosuccinate synthetase (ASS1) gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia: A Children's Oncology Group Study [corrected]

8 July 2018

1 reference

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Concordant gene expression in leukemia cells and normal leukocytes is associated with germline cis-SNPs

8 July 2018

1 reference

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Genetic alterations determine chemotherapy resistance in childhood T-ALL: modelling in stage-specific cell lines and correlation with diagnostic patient samples

8 July 2018

1 reference

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Identification of genetic variants contributing to cisplatin-induced cytotoxicity by use of a genomewide approach

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Expression of SMARCB1 modulates steroid sensitivity in human lymphoblastoid cells: identification of a promoter SNP that alters PARP1 binding and SMARCB1 expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Correlation between asparaginase sensitivity and asparagine synthetase protein content, but not mRNA, in acute lymphoblastic leukemia cell lines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Using HapMap tools in pharmacogenomic discovery: the thiopurine methyltransferase polymorphism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

New therapeutic strategies for the treatment of acute lymphoblastic leukaemia

8 July 2018

1 reference

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Authenticity and drug resistance in a panel of acute lymphoblastic leukaemia cell lines

8 July 2018

1 reference

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Biologic pathways associated with relapse in childhood acute lymphoblastic leukemia: a Children's Oncology Group study

8 July 2018

1 reference

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Treatment of acute lymphoblastic leukemia

8 July 2018

1 reference

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The expression of 70 apoptosis genes in relation to lineage, genetic subtype, cellular drug resistance, and outcome in childhood acute lymphoblastic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Asparagine synthetase expression is linked with L-asparaginase resistance in TEL-AML1-negative but not TEL-AML1-positive pediatric acute lymphoblastic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

A genome-wide view of the in vitro response to l-asparaginase in acute lymphoblastic leukemia.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Asparagine synthetase expression alone is sufficient to induce l-asparaginase resistance in MOLT-4 human leukaemia cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Improved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium Protocol 91-01.

8 July 2018

1 reference

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Improved outcome in childhood acute lymphoblastic leukemia despite reduced use of anthracyclines and cranial radiotherapy: results of trial ALL-BFM 90. German-Austrian-Swiss ALL-BFM Study Group

8 July 2018

1 reference

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A gene expression database for the molecular pharmacology of cancer

8 July 2018

1 reference

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Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): mechanisms for the genetic polymorphism of TPMT activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Amino acid control of asparagine synthetase: relation to asparaginase resistance in human leukemia cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Purine and pyrimidine metabolism in human gliomas: relation to chromosomal aberrations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Asparagine synthetase activity of mouse leukemias

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

l-Asparaginase resistance in human leukemia—Asparagine synthetase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Adaptation of the rapid automated tetrazolium dye based (MTT) assay for chemosensitivity testing in childhood leukemia.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

In vitro and in vivo killing of acute lymphoblastic leukemia cells by L-asparaginase.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Relation of cellular drug resistance to long-term clinical outcome in childhood acute lymphoblastic leukaemia.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Pharmacokinetic, pharmacodynamic and intracellular effects of PEG-asparaginase in newly diagnosed childhood acute lymphoblastic leukemia: results from a single agent window study

8 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.256

Upregulation of asparagine synthetase fails to avert cell cycle arrest induced by L-asparaginase in TEL/AML1-positive leukaemic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.256

Sensitivity to L-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+ pediatric ALL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.256

Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.256

Identifying Important Risk Factors for Survival in Kidney Graft Failure Patients Using Random Survival Forests

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.256

Argininosuccinate synthetase gene expression in leukemias: potential diagnostic marker for blastic crisis of chronic myelocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.256

Isolation of a human thiopurine S-methyltransferase (TPMT) complementary DNA with a single nucleotide transition A719G (TPMT*3C) and its association with loss of TPMT protein and catalytic activity in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.256

TEL/AML1 gene fusion is related to in vitro drug sensitivity for L-asparaginase in childhood acute lymphoblastic leukemia.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Favorable prognosis of hyperdiploid common acute lymphoblastic leukemia may be explained by sensitivity to antimetabolites and other drugs: results of an in vitro study.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

In vitro drug sensitivity of cells from children with leukemia using the MTT assay with improved culture conditions.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097057

Weekly polyethylene glycol conjugated L-asparaginase compared with biweekly dosing produces superior induction remission rates in childhood relapsed acute lymphoblastic leukemia: a Pediatric Oncology Group Study

26 October 2018

1 reference

12 December 2020

L-asparaginase: clinical, biochemical, pharmacological, and immunological studies

1 reference

12 December 2020

Identification of the enzymatic pathways of nucleotide metabolism in human lymphocytes and leukemia cells

1 reference

12 December 2020

Nucleoside incorporation into DNA and RNA in acute leukaemia: differences between the various leukaemia sub-types

1 reference

12 December 2020

Enzymes of purine metabolism in cancer

1 reference

12 December 2020

Adenylosuccinate lyase as an indicator of breast and prostate malignancies: a preliminary report

1 reference

12 December 2020

Biochemical characterization of U937 cells resistant to L-asparaginase: the role of asparagine synthetase

1 reference

12 December 2020

In vitro drug sensitivity testing can predict induction failure and early relapse of childhood acute lymphoblastic leukemia

1 reference

12 December 2020

In vitro cellular drug resistance and prognosis in newly diagnosed childhood acute lymphoblastic leukemia

1 reference

12 December 2020

Acute lymphoblastic leukemia

1 reference

12 December 2020

Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia--implications for treatment of infants

1 reference

12 December 2020

Prognostic significance of early response to a single dose of asparaginase in childhood acute lymphoblastic leukemia

1 reference

12 December 2020

Identifiers

DOI

10.1038/LEU.2010.256

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21072045%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

16 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21072045%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference