(Q34992740)

5 August 2017

title

Identification of residues in the human respiratory syncytial virus fusion protein that modulate fusion activity and pathogenesis (English)

1 reference

respiratory syncytial virus

5 August 2017

main subject

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RSV precursor fusion glycoprotein F0

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Anne L Hotard

1

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James E. Crowe, Jr.

object named as

James E Crowe

4

0 references

Richard K Plemper

8

object named as

Richard K Plemper

1 reference

5 August 2017

7

R Stokes Peebles

1 reference

5 August 2017

6

Dawn C Newcomb

1 reference

5 August 2017

9

Martin L Moore

1 reference

5 August 2017

Sujin Lee

2

1 reference

5 August 2017

Michael G Currier

3

1 reference

5 August 2017

Kaori Sakamoto

5

1 reference

5 August 2017

language of work or name

English

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publication date

22 October 2014

1 reference

5 August 2017

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5 August 2017

volume

89

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5 August 2017

issue

1

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5 August 2017

page(s)

512-522

1 reference

IL-17E (IL-25) and IL-17RB promote respiratory syncytial virus-induced pulmonary disease

5 August 2017

cites work

1 reference

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A single amino acid in the F2 subunit of respiratory syncytial virus fusion protein alters growth and fusogenicity

8 July 2018

1 reference

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Autophagy-inducing protein beclin-1 in dendritic cells regulates CD4 T cell responses and disease severity during respiratory syncytial virus infection

8 July 2018

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A respiratory syncytial virus (RSV) anti-G protein F(ab')2 monoclonal antibody suppresses mucous production and breathing effort in RSV rA2-line19F-infected BALB/c mice

8 July 2018

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The respiratory syncytial virus fusion protein and neutrophils mediate the airway mucin response to pathogenic respiratory syncytial virus infection

8 July 2018

1 reference

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Point mutations in the paramyxovirus F protein that enhance fusion activity shift the mechanism of complement-mediated virus neutralization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

A stabilized respiratory syncytial virus reverse genetics system amenable to recombination-mediated mutagenesis

8 July 2018

1 reference

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Structure of the primed paramyxovirus fusion protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Generation of a dual-functional split-reporter protein for monitoring membrane fusion using self-associating split GFP.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Mechanisms of respiratory syncytial virus modulation of airway immune responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Hospitalizations associated with influenza and respiratory syncytial virus in the United States, 1993-2008.

8 July 2018

1 reference

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Respiratory syncytial virus load, viral dynamics, and disease severity in previously healthy naturally infected children

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Differential pathogenesis of respiratory syncytial virus clinical isolates in BALB/c mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Viral load drives disease in humans experimentally infected with respiratory syncytial virus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Conformational changes of the HIV-1 envelope protein during membrane fusion are inhibited by the replacement of its membrane-spanning domain.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Residues in the heptad repeat a region of the fusion protein modulate the virulence of Sendai virus in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

A conserved region in the F(2) subunit of paramyxovirus fusion proteins is involved in fusion regulation

8 July 2018

1 reference

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Functional analysis of the N-linked glycans within the fusion protein of respiratory syncytial virus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Spring-loaded heptad repeat residues regulate the expression and activation of paramyxovirus fusion protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

The histopathology of fatal untreated human respiratory syncytial virus infection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Differential immune responses and pulmonary pathophysiology are induced by two different strains of respiratory syncytial virus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Sequence elements of the fusion peptide of human respiratory syncytial virus fusion protein required for activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Deletion of TLR3 alters the pulmonary immune environment and mucus production during respiratory syncytial virus infection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Targeting a binding pocket within the trimer-of-hairpins: small-molecule inhibition of viral fusion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

UCSF Chimera--a visualization system for exploratory research and analysis

8 July 2018

1 reference

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Mutations in the putative HR-C region of the measles virus F2 glycoprotein modulate syncytium formation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Role of interleukin-12 and stat-4 in the regulation of airway inflammation and hyperreactivity in respiratory syncytial virus infection

8 July 2018

1 reference

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N-glycans of F protein differentially affect fusion activity of human respiratory syncytial virus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Immunological properties of plaque purified strains of live attenuated respiratory syncytial virus (RSV) for human vaccine

8 July 2018

1 reference

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Development of a humanized monoclonal antibody (MEDI-493) with potent in vitro and in vivo activity against respiratory syncytial virus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Pathological changes in virus infections of the lower respiratory tract in children

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301159

Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation

8 July 2018

1 reference

https://api.crossref.org/works/10.1128%2FJVI.02472-14

The respiratory syncytial virus fusion protein targets to the perimeter of inclusion bodies and facilitates filament formation by a cytoplasmic tail-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1128%2FJVI.02472-14

Safety, tolerability, pharmacokinetics, and immunogenicity of motavizumab, a humanized, enhanced-potency monoclonal antibody for the prevention of respiratory syncytial virus infection in at-risk children

21 January 2018

1 reference

https://api.crossref.org/works/10.1128%2FJVI.02472-14

Natural infection of infants with respiratory syncytial virus subgroups A and B: a study of frequency, disease severity, and viral load

21 January 2018

1 reference

https://api.crossref.org/works/10.1128%2FJVI.02472-14

Respiratory syncytial virus load predicts disease severity in previously healthy infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1128%2FJVI.02472-14

CXCR2 regulates respiratory syncytial virus-induced airway hyperreactivity and mucus overproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1128%2FJVI.02472-14

Deletion of CCR1 attenuates pathophysiologic responses during respiratory syncytial virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1128%2FJVI.02472-14

MyD88-mediated instructive signals in dendritic cells regulate pulmonary immune responses during respiratory virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1128%2FJVI.02472-14

21 January 2018

Identifiers

DOI

10.1128/JVI.02472-14

1 reference

5 August 2017

1 reference

5 August 2017

1 reference