(Q34992789)

5 August 2017

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title

Radiation-induced tumour necrosis factor-alpha expression: clinical application of transcriptional and physical targeting of gene therapy (English)

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5 August 2017

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1

Ralph R Weichselbaum

1 reference

5 August 2017

7

Helena J Mauceri

1 reference

5 August 2017

Donald W Kufe

2

1 reference

5 August 2017

Samuel Hellman

3

1 reference

5 August 2017

Henrik S Rasmussen

4

1 reference

5 August 2017

C Richter King

5

1 reference

5 August 2017

Paul H Fischer

6

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5 August 2017

1 November 2002

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Lancet Oncology Commission

5 August 2017

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5 August 2017

3

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5 August 2017

665-671

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5 August 2017

11

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Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN.

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Ionizing radiation regulates expression of the c-jun protooncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Induction of the expression of the interleukin-1 beta gene in mouse spleen by ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Cloning of rat GADD45 gene and induction analysis following ionizing radiation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Ionizing radiation activates transcription of the EGR1 gene via CArG elements

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Involvement of reactive oxygen intermediates in the induction of c-jun gene transcription by ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Significance analysis of microarrays applied to the ionizing radiation response

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Transgene expression in malignant glioma using a replication-defective adenoviral vector containing the Egr-1 promoter: activation by ionizing radiation or uptake of radioactive iododeoxyuridine

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Development of synthetic promoters for radiation-mediated gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Early growth response-1 gene (Egr-1) promoter induction by ionizing radiation in U87 malignant glioma cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Tumor necrosis factor. Characterization at the molecular, cellular and in vivo level

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Tumor necrosis factor receptors--structure and function

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

A novel domain within the 55 kd TNF receptor signals cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Tumor necrosis factor (TNF).

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

An endotoxin-induced serum factor that causes necrosis of tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Enhanced responsiveness of endothelium in the growing/motile state to tumor necrosis factor/cachectin

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Tumor necrosis factor/cachectin-induced intravascular fibrin formation in meth A fibrosarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Recombinant human tumor necrosis factor-alpha: thrombus formation is a cause of anti-tumor activity

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

The antitumor function of tumor necrosis factor (TNF), I. Therapeutic action of TNF against an established murine sarcoma is indirect, immunologically dependent, and limited by severe toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Early endothelium activation and polymorphonuclear cell invasion precede specific necrosis of human melanoma and sarcoma treated by intravascular high-dose tumour necrosis factor alpha (rTNF alpha)

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

A phase I study of local treatment of liver metastases with recombinant tumour necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Recombinant human tumor necrosis factor increases mRNA levels and surface expression of HLA-A,B antigens in vascular endothelial cells and dermal fibroblasts in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Clinical pharmacology of recombinant human tumor necrosis factor in patients with advanced cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Recombinant Human Tumor Necrosis Factor Administered as a 24-Hour Intravenous Infusion. A Phase I and Pharmacologic Study

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Transfer of genes to humans: early lessons and obstacles to success

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Gene therapy of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Spatial and temporal control of gene therapy using ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Tumor production of angiostatin is enhanced after exposure to TNF-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Generation of Angiostatin by Reduction and Proteolysis of Plasmin

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Regulation of angiostatin production by matrix metalloproteinase-2 in a model of concomitant resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Angiostatin-converting enzyme activities of human matrilysin (MMP-7) and gelatinase B/type IV collagenase (MMP-9)

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Combined effects of angiostatin and ionizing radiation in antitumour therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

A radiation-controlled molecular switch for use in gene therapy of cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Activation of the radiosensitive EGR-1 promoter induces expression of the herpes simplex virus thymidine kinase gene and sensitivity of human glioma cells to ganciclovir

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Induction of the suicide HSV-TK gene by activation of the Egr-1 promoter with radioisotopes

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Regression of hepatocellular carcinoma in vitro and in vivo by radiosensitizing suicide gene therapy under the inducible and spatial control of radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Modification of vascular tone using iNOS under the control of a radiation-inducible promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

Intratumoral administration of low doses of an adenovirus vector encoding tumor necrosis factor alpha together with naive dendritic cells elicits significant suppression of tumor growth without toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2802%2900900-2

7 January 2021

10.1016/S1470-2045(02)00900-2

Identifiers

DOI

1 reference

5 August 2017

1 reference