(Q34996260)

5 August 2017

title

Pathway-based outlier method reveals heterogeneous genomic structure of autism in blood transcriptome (English)

1 reference

5 August 2017

0 references

0 references

2

Isaac S Kohane

1 reference

5 August 2017

Malcolm G Campbell

1

1 reference

5 August 2017

Sek Won Kong

series ordinal

3

1 reference

5 August 2017

publication date

24 September 2013

1 reference

5 August 2017

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5 August 2017

volume

6

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5 August 2017

page(s)

34

1 reference

https://scigraph.springernature.com/pub.10.1186/1755-8794-6-34

5 August 2017

exact match

0 references

cites work

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Pathway-based classification of cancer subtypes

8 July 2018

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Genome-wide transcriptome profiling reveals the functional impact of rare de novo and recurrent CNVs in autism spectrum disorders.

8 July 2018

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8 July 2018

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The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

8 July 2018

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Patterns and rates of exonic de novo mutations in autism spectrum disorders

8 July 2018

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Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

8 July 2018

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De novo mutations revealed by whole-exome sequencing are strongly associated with autism

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Interaction between FEZ1 and DISC1 in regulation of neuronal development and risk for schizophrenia

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

KEGG for integration and interpretation of large-scale molecular data sets

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Autism and increased paternal age related changes in global levels of gene expression regulation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

GTI: a novel algorithm for identifying outlier gene expression profiles from integrated microarray datasets

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Altered functional connectivity in frontal lobe circuits is associated with variation in the autism risk gene CNTNAP2

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Defective GABAergic neurotransmission and pharmacological rescue of neuronal hyperexcitability in the amygdala in a mouse model of fragile X syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Functional impact of global rare copy number variation in autism spectrum disorders

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Genetic heterogeneity in human disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

A pathway-based classification of human breast cancer.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Finding the missing heritability of complex diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Gene expression profiling differentiates autism case-controls and phenotypic variants of autism spectrum disorders: evidence for circadian rhythm dysfunction in severe autism.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

AutDB: a gene reference resource for autism research

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Reactome knowledgebase of human biological pathways and processes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Imbalance of neocortical excitation and inhibition and altered UP states reflect network hyperexcitability in the mouse model of fragile X syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Altered gene expression and function of peripheral blood natural killer cells in children with autism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Cancer outlier detection based on likelihood ratio test

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Synaptic imbalance, stereotypies, and impaired social interactions in mice with altered neuroligin 2 expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Genomic outlier profile analysis: mixture models, null hypotheses, and nonparametric estimation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Advances in autism genetics: on the threshold of a new neurobiology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Immune transcriptome alterations in the temporal cortex of subjects with autism.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Structural variation of chromosomes in autism spectrum disorder

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Disruption of neurexin 1 associated with autism spectrum disorder

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Capturing heterogeneity in gene expression studies by surrogate variable analysis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Biology of RANK, RANKL, and osteoprotegerin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Human disease classification in the postgenomic era: a complex systems approach to human pathobiology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Strong association of de novo copy number mutations with autism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Mapping autism risk loci using genetic linkage and chromosomal rearrangements

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

A multivariate approach for integrating genome-wide expression data and biological knowledge

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Minicolumnar abnormalities in autism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

The developmental neurobiology of autism spectrum disorder.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Gene expression profiling of lymphoblastoid cell lines from monozygotic twins discordant in severity of autism reveals differential regulation of neurologically relevant genes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Adjusting batch effects in microarray expression data using empirical Bayes methods

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

When is the brain enlarged in autism? A meta-analysis of all brain size reports

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Why the frontal cortex in autism might be talking only to itself: local over-connectivity but long-distance disconnection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Statistical significance for genomewide studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Linkage and association of the glutamate receptor 6 gene with autism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Postmortem brain abnormalities of the glutamate neurotransmitter system in autism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Gene ontology: tool for the unification of biology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

KEGG: kyoto encyclopedia of genes and genomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

F-spondin and mindin: two structurally and functionally related genes expressed in the hippocampus that promote outgrowth of embryonic hippocampal neurons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849321

Addressing genetic heterogeneity in complex disease: finding seizure genes in systemic lupus erythematosus

8 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

Gene expression changes in children with autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

Outlier Detection in Axis-Parallel Subspaces of High Dimensional Data

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

COPA--cancer outlier profile analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

Cancer outlier differential gene expression detection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

MOST: detecting cancer differential gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

Association of DISC1 with autism and Asperger syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

Evidence of brain overgrowth in the first year of life in autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

Clinical, morphological, and biochemical correlates of head circumference in autism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

White matter structure in autism: preliminary evidence from diffusion tensor imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

Diffusion tensor imaging of the corpus callosum in Autism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

CACNA1H mutations in autism spectrum disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

The central role of the propensity score in observational studies for causal effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

A Fast Algorithm for the Minimum Covariance Determinant Estimator

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

Robust Regression and Outlier Detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-6-34

Outlier sums for differential gene expression analysis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24063311

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1755-8794-6-34

1 reference

Dimensions Publication ID

5 August 2017

0 references

1 reference

5 August 2017

1 reference