(Q34996618)

5 August 2017

1 reference

title

Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis (English)

1 reference

5 August 2017

Tucker T

1

1 reference

PubMed ID

12431247

5 August 2017

Friedman JM

series ordinal

2

1 reference

PubMed ID

12431247

5 August 2017

language of work or name

1 reference

1 November 2002

1 reference

5 August 2017

1 reference

5 August 2017

62

1 reference

5 August 2017

345-357

1 reference

5 August 2017

5

1 reference

Retinoma: spontaneous regression of retinoblastoma or benign manifestation of the mutation?

5 August 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

New developments in the neurobiology of the tuberous sclerosis complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

Hyperactive Ras as a therapeutic target in neurofibromatosis type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromas

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

Significance of Retinoma and Phthisis Bulbi for Retinoblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

Neurofibromatosis type 1: piecing the puzzle together

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

Multiple Cell Origin of Hereditary Neurofibromas

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

Mutation and cancer: statistical study of retinoblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

1 reference

7 January 2021

Chasing the cancer demon

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Neurofibromatosis 2: loss of merlin's protective spell

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

The multistep nature of cancer

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Gene action in the X-chromosome of the mouse (Mus musculus L.)

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

X-chromosome inactivation and developmental patterns in mammals

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Primordial cell pool size and lineage relationships of five human cell types.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

The retinoblastoma gene product is bound in the nucleus in early G1 phase

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Speculations on the roles of RB1 in tissue-specific differentiation, tumor initiation, and tumor progression.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Mechanisms of loss of heterozygosity in retinoblastoma

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

A detailed analysis of chromosomal changes in heritable and non-heritable retinoblastoma.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Isochromosome 6p, a unique chromosomal abnormality in retinoblastoma: Verification by standard staining techniques, new densitometric methods, and somatic cell hybridization

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Mechanism of i(6p) formation in retinoblastoma tumor cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Molecular genetic advances in tuberous sclerosis

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Apparent preferential loss of heterozygosity at TSC2 over TSC1 chromosomal region in tuberous sclerosis hamartomas

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Clonality of tuberous sclerosis harmatomas shown by non-random X-chromosome inactivation.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Loss of heterozygosity in tuberous sclerosis hamartomas.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Complete inactivation of the TSC2 gene leads to formation of hamartomas

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Survey of somatic mutations in tuberous sclerosis complex (TSC) hamartomas suggests different genetic mechanisms for pathogenesis of TSC lesions

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Genomic organization of the neurofibromatosis 1 gene (NF1).

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuropeptides

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Rescue of a Drosophila NF1 mutant phenotype by protein kinase A.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Minor lesion mutational spectrum of the entire NF1 gene does not explain its high mutability but points to a functional domain upstream of the GAP-related domain

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

A neurofibromatosis-1-regulated pathway is required for learning in Drosophila

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

New function for NF1 tumor suppressor

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Loss of NF1 allele in Schwann cells but not in fibroblasts derived from an NF1-associated neurofibroma

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Clonal origin of tumor cells in a plexiform neurofibroma with LOH in NF1 intron 38 and in dermal neurofibromas without LOH of the NF1 gene

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Benign neurofibromas in type 1 neurofibromatosis (NF1) show somatic deletions of the NF1 gene

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Schwann cells harbor the somatic NF1 mutation in neurofibromas: evidence of two different Schwann cell subpopulations

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Chromosome 17 loss-of-heterozygosity studies in benign and malignant tumors in neurofibromatosis type 1

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Toward a survey of somatic mutation of the NF1 gene in benign neurofibromas of patients with neurofibromatosis type 1.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Genetic and cellular defects contributing to benign tumor formation in neurofibromatosis type 1

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Identification of NF1 mutations in both alleles of a dermal neurofibroma

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

A search for evidence of somatic mutations in the NF1 gene.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Confirmation of a double-hit model for the NF1 gene in benign neurofibromas

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Histogenesis control genes and neurofibromatosis 1.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Neurofibromatosis type 1: II. Answers from animal models

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Upregulation of tumor suppressor protein neurofibromin in normal human wound healing and in vitro evidence for platelet derived growth factor (PDGF) and transforming growth factor-beta1 (TGF-beta1) elicited increase in neurofibromin mRNA steady-stat

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Culture of cytogenetically abnormal schwann cells from benign and malignant NF1 tumors

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Neurofibromas in NF1: Schwann cell origin and role of tumor environment

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Pathology of tumors of the peripheral nerve sheath in type 1 neurofibromatosis

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Mortality in neurofibromatosis 1: an analysis using U.S. death certificates.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Molecular and cytogenetic analysis of tumors in von Recklinghausen neurofibromatosis

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Alterations at chromosome 17 loci in peripheral nerve sheath tumors

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

TP53 mutations are frequent in malignant NF1 tumors

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

The neurofibromatosis type I messenger RNA undergoes base-modification RNA editing

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Mouse tumor model for neurofibromatosis type 1

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Synergistic interactions between transforming growth factor beta and fibroblast growth factor regulate Schwann cell mitosis

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Hepatocyte growth factor is a mitogen for Schwann cells and is present in neurofibromas

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

Malignant peripheral nerve sheath tumour arising within neurofibroma. An immunohistochemical analysis in the comparison between benign and malignant components

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620501.X

7 January 2021

10.1034/J.1399-0004.2002.620501.X

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12431247