(Q35788019)

10 August 2017

Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromas (English)

1 reference

10 August 2017

2

I Orlow

1 reference

10 August 2017

H P Kourea

1

1 reference

10 August 2017

B W Scheithauer

series ordinal

3

1 reference

10 August 2017

C Cordon-Cardo

series ordinal

4

1 reference

10 August 2017

J M Woodruff

series ordinal

5

1 reference

10 August 2017

language of work or name

English

0 references

publication date

1 December 1999

1 reference

The American Journal of Pathology

10 August 2017

1 reference

10 August 2017

155

1 reference

10 August 2017

1855-1860

1 reference

10 August 2017

6

1 reference

Expression of p27(kip) and other cell cycle regulators in malignant peripheral nerve sheath tumors and neurofibromas: the emerging role of p27(kip) in malignant transformation of neurofibromas

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Alterations of INK4A and INK4B genes in adult soft tissue sarcomas: effect on survival

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Loss of heterozygosity on chromosome 9q21 (p16 gene) uncommon in soft-tissue sarcomas

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Hypermethylation of the CpG island of p16/CDKN2 correlates with gene inactivation in gliomas.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

High frequency of aberrant p16(INK4A) expression in human breast cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

A cell cycle regulator potentially involved in genesis of many tumor types

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Deletion of p16 and p15 genes in brain tumors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Germline p16 mutations in familial melanoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Higher frequency of alterations in the p16/CDKN2 gene in squamous cell carcinoma cell lines than in primary tumors of the head and neck.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Immunohistochemical and molecular analysis of p53, MDM2, proliferating cell nuclear antigen and Ki67 in benign and malignant peripheral nerve sheath tumours.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Malignant peripheral nerve sheath tumors. A clinicopathologic study of 120 cases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Infrequent alterations of the p15, p16, CDK4 and cyclin D1 genes in non-astrocytic human brain tumors.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Deletion map of chromosome 9 and p16 (CDKN2A) gene alterations in neuroblastoma.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Homozygous deletions of the multiple tumor suppressor gene 1 in the progression of human astrocytomas.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866948

Deletion of the p16 and p15 Genes in Human Bladder Tumors

25 September 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965504-6

Malignant peripheral nerve sheath tumors of the buttock and lower extremity. A study of 43 cases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965504-6

Subdiaphragmatic and intrathoracic paraspinal malignant peripheral nerve sheath tumors: a clinicopathologic study of 25 patients and 26 tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965504-6

TP53 mutations are frequent in malignant NF1 tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965504-6

p53 expression in neurofibroma and malignant peripheral nerve sheath tumor. An immunohistochemical study of sporadic and NF1-associated tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965504-6

Absence of p16/MTS1 gene mutations in human prostate cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965504-6

Mutational analysis of the p16 gene in human neuroblastomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965504-6

Cooperative tumorigenic effects of germline mutations in Rb and p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965504-6

Cooperative effects of p53 and pRB alterations in primary superficial bladder tumors

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10595915

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/S0002-9440(10)65504-6

1 reference

10 August 2017

1 reference

10 August 2017

1 reference