(Q34996707)

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Towards the small and the beautiful: a small dibromotyrosine derivative from Pseudoceratina sp. sponge exhibits potent apoptotic effect through targeting IKK/NFκB signaling pathway

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scholarly article

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Europe PubMed Central

5 August 2017

Towards the small and the beautiful: a small dibromotyrosine derivative from Pseudoceratina sp. sponge exhibits potent apoptotic effect through targeting IKK/NFκB signaling pathway (English)

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5 August 2017

apoptotic process

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12

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14 June 2020

author name string

Jui-Hsin Su

1

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14 June 2020

Yu-Cheng Chen

2

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14 June 2020

Mohamed El-Shazly

3

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14 June 2020

Ying-Chi Du

4

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14 June 2020

Chiang-Wen Su

5

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14 June 2020

Chia-Wei Tsao

6

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14 June 2020

Li-Lian Liu

7

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14 June 2020

Yalan Chou

8

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14 June 2020

Wen-Been Chang

9

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14 June 2020

Yin-Di Su

10

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14 June 2020

Michael Y Chiang

11

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14 June 2020

Mei-Chin Lu

13

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14 June 2020

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26 August 2013

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5 August 2017

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14 June 2020

11

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14 June 2020

9

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14 June 2020

3168-3185

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14 June 2020

copyright license

Creative Commons Attribution 4.0 International

26 August 2013

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April 2022 Public Data File from Crossref

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Brominated skeletal components of the marine demosponges, Aplysina cavernicola and Ianthella basta: analytical and biochemical investigations

1 reference

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8 July 2018

Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21(Cip1) downregulation are required for shikonin-induced apoptosis

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Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis

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The brominated compound aeroplysinin-1 inhibits proliferation and the expression of key pro- inflammatory molecules in human endothelial and monocyte cells

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The antiangiogenic compound aeroplysinin-1 induces apoptosis in endothelial cells by activating the mitochondrial pathway.

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NF-κB as potential target in the treatment of melanoma

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Antiparasitic bromotyrosine derivatives from the marine sponge Verongula rigida.

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Role of oxidative stress and DNA damage in human carcinogenesis

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A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis

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Design, synthesis, and biological evaluation of dibromotyrosine analogues inspired by marine natural products as inhibitors of human prostate cancer proliferation, invasion, and migration

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Bioactive sesterterpenes and triterpenes from marine sponges: occurrence and pharmacological significance

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Constitutive HIF-1 activity in malignant melanoma.

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8 July 2018

Antiplasmodial activities of homogentisic acid derivative protein kinase inhibitors isolated from a Vanuatu marine sponge Pseudoceratina sp

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PARP-1 inhibition-induced activation of PI-3-kinase-Akt pathway promotes resistance to taxol.

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PTEN, more than the AKT pathway

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PI 3-kinase, Akt and cell survival

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[Synthetic lethality as a new concept for the treatment of cancer].

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26 October 2018

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1 reference

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Syntheses of pseudoceramines A-D and a new synthesis of spermatinamine, bromotyrosine natural products from marine sponges

1 reference

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12 December 2020

based on heuristic

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Total synthesis of psammaplysenes A and B, naturally occurring inhibitors of FOXO1a nuclear export

1 reference

https://pubmed.ncbi.nlm.nih.gov/24065159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiangiogenic versus cytotoxic activity in analogues of aeroplysinin-1

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The discovery of 2-amino-3,5-diarylbenzamide inhibitors of IKK-alpha and IKK-beta kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/24065159

12 December 2020

based on heuristic

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Unequivocal 13C NMR assignment of cyclohexadienyl rings in bromotyrosine-derived metabolites from marine sponges

1 reference

https://pubmed.ncbi.nlm.nih.gov/24065159

12 December 2020

based on heuristic

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Identifiers

10.3390/MD11093168

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14 June 2020

1 reference

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14 June 2020

1 reference

Europe PubMed Central

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14 June 2020

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