(Q34997136)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431841%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

review article

1 reference

title

Role of Akt/protein kinase B in metabolism (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431841%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

3

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14 December 2019

author name string

Eileen L Whiteman

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431841%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Han Cho

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431841%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

publication date

1 December 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431841%20AND%20SRC:MED&resulttype=core&format=json

Trends in Endocrinology and Metabolism

14 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431841%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431841%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

page(s)

444-451

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431841%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

issue

10

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431841%20AND%20SRC:MED&resulttype=core&format=json

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

14 December 2019

cites work

1 reference

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7 January 2021

Insulin increases the association of Akt-2 with Glut4-containing vesicles

1 reference

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7 January 2021

A role for protein kinase Bbeta/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes

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7 January 2021

Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts

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7 January 2021

Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide.

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7 January 2021

Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells.

1 reference

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7 January 2021

Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport

1 reference

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7 January 2021

Stimulation of IRS-1-associated phosphatidylinositol 3-kinase and Akt/protein kinase B but not glucose transport by beta1-integrin signaling in rat adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes

1 reference

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7 January 2021

Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes

1 reference

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7 January 2021

An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes

1 reference

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7 January 2021

CAP defines a second signalling pathway required for insulin-stimulated glucose transport

1 reference

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7 January 2021

Mice with gene disruption of both endothelial and neuronal nitric oxide synthase exhibit insulin resistance.

1 reference

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7 January 2021

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

1 reference

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7 January 2021

4E-BP1 and S6K1: translational integration sites for nutritional and hormonal information in muscle

1 reference

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7 January 2021

Regulation of translation initiation by FRAP/mTOR

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7 January 2021

Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis

1 reference

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7 January 2021

Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells

1 reference

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7 January 2021

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

1 reference

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7 January 2021

Requirement for Akt (protein kinase B) in insulin-induced activation of glycogen synthase and phosphorylation of 4E-BP1 (PHAS-1)

1 reference

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7 January 2021

Construction and characterization of a conditionally active version of the serine/threonine kinase Akt.

1 reference

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7 January 2021

Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Phosphorylation of recombinant human ATP:citrate lyase by cAMP-dependent protein kinase abolishes homotropic allosteric regulation of the enzyme by citrate and increases the enzyme activity. Allosteric activation of ATP:citrate lyase by phosphorylat

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

PKB Inhibition Prevents the Stimulatory Effect of Insulin on Glucose Transport and Protein Translocation but Not the Antilipolytic Effect in Rat Adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Insulin regulation of phosphoenolpyruvate carboxykinase gene expression does not require activation of the Ras/mitogen-activated protein kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Phosphatidylinositol 3-Kinase, but Not p70/p85 Ribosomal S6 Protein Kinase, Is Required for the Regulation of Phosphoenolpyruvate Carboxykinase (PEPCK) Gene Expression by Insulin

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Activation of protein kinase B/Akt is sufficient to repress the glucocorticoid and cAMP induction of phosphoenolpyruvate carboxykinase gene.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Assessment of the roles of mitogen-activated protein kinase, phosphatidylinositol 3-kinase, protein kinase B, and protein kinase C in insulin inhibition of cAMP-induced phosphoenolpyruvate carboxykinase gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

1 reference

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7 January 2021

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Negative regulation of the forkhead transcription factor FKHR by Akt.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Differential regulation of endogenous glucose-6-phosphatase and phosphoenolpyruvate carboxykinase gene expression by the forkhead transcription factor FKHR in H4IIE-hepatoma cells.

1 reference

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7 January 2021

Gene- and activation-specific mechanisms for insulin inhibition of basal and glucocorticoid-induced insulin-like growth factor binding protein-1 and phosphoenolpyruvate carboxykinase transcription. Roles of forkhead and insulin response sequences

1 reference

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7 January 2021

Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin. The role of winged helix/forkhead proteins

1 reference

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7 January 2021

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

1 reference

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7 January 2021

Transcriptional effects of chronic Akt activation in the heart.

1 reference

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7 January 2021

IRS proteins and beta-cell function

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Enhanced expression of insulin receptor substrate-2 and activation of protein kinase B/Akt in regenerating pancreatic duct epithelium of 60 %-partial pancreatectomy rats

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Protein kinase B is expressed in pancreatic beta cells and activated upon stimulation with insulin-like growth factor I

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Impaired glucose transport and protein kinase B activation by insulin, but not okadaic acid, in adipocytes from subjects with Type II diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Normal Akt/PKB with reduced PI3K activation in insulin-resistant mice

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Divergent regulation of Akt1 and Akt2 isoforms in insulin target tissues of obese Zucker rats

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Diabetes. Dialogue between muscle and fat.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900662-8

7 January 2021

10.1016/S1043-2760(02)00662-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431841%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

1 reference