(Q34997326)

5 August 2017

title

Acetaminophen hepatotoxicity and HIF-1α induction in acetaminophen toxicity in mice occurs without hypoxia (English)

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5 August 2017

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7

Laura P James

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5 August 2017

2

Sandra S McCullough

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5 August 2017

5

Pippa M Simpson

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5 August 2017

4

Lynda Letzig

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5 August 2017

Shubhra Chaudhuri

1

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5 August 2017

Leah Hennings

series ordinal

3

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5 August 2017

Jack A Hinson

series ordinal

6

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5 August 2017

publication date

24 February 2011

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Toxicology and Applied Pharmacology

5 August 2017

published in

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5 August 2017

volume

252

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5 August 2017

issue

3

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5 August 2017

page(s)

211-220

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Human recombinant vascular endothelial growth factor reduces necrosis and enhances hepatocyte regeneration in a mouse model of acetaminophen toxicity

5 August 2017

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Mice deficient in Cu,Zn-superoxide dismutase are resistant to acetaminophen toxicity

8 July 2018

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8 July 2018

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Low-level arsenite activates the transcription of genes involved in adipose differentiation

8 July 2018

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Involvement of mitochondrial permeability transition in acetaminophen-induced liver injury in mice

8 July 2018

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Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes

8 July 2018

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Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins

8 July 2018

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Modes of Cell Death in Rat Liver after Monocrotaline Exposure

8 July 2018

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Signal transduction to hypoxia-inducible factor 1

8 July 2018

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Hypoxia and perfusion measurements in human tumors--initial experience with pimonidazole and IUdR.

8 July 2018

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Mitochondrial ROS metabolism: modulation by uncoupling proteins.

8 July 2018

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Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arsenite

8 July 2018

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Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches

8 July 2018

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Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

8 July 2018

1 reference

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The hepatic inflammatory response after acetaminophen overdose: role of neutrophils

8 July 2018

1 reference

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Nitrotyrosine-protein adducts in hepatic centrilobular areas following toxic doses of acetaminophen in mice

8 July 2018

1 reference

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Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury

8 July 2018

1 reference

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The mitochondrial permeability transition in toxic, hypoxic and reperfusion injury

8 July 2018

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Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver

8 July 2018

1 reference

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Paracetamol-stimulated lipid peroxidation in isolated rat and mouse hepatocytes

8 July 2018

1 reference

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Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo

8 July 2018

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Early sustained rise in total liver calcium during acetaminophen hepatotoxicity in mice.

8 July 2018

1 reference

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Liposome-encapsulated superoxide dismutase prevents liver necrosis induced by acetaminophen

8 July 2018

1 reference

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Immunohistochemical localization and quantification of the 3-(cystein-S-yl)-acetaminophen protein adduct in acetaminophen hepatotoxicity

8 July 2018

1 reference

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Oxidative and reductive metabolism by cytochrome P450 2E1.

8 July 2018

1 reference

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Role of reactive oxygen species in cell toxicity

8 July 2018

1 reference

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Induction of the nuclear factor HIF-1alpha in acetaminophen toxicity: evidence for oxidative stress

8 July 2018

1 reference

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Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099476

Dual role of vascular endothelial growth factor in hepatic ischemia-reperfusion injury.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099476

Mechanisms of acetaminophen-induced hepatotoxicity: role of oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099476

Early hepatic microvascular injury in response to acetaminophen toxicity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099476

Angiogenesis-independent endothelial protection of liver: role of VEGFR-1.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099476

Reduced hepatotoxicity of acetaminophen in mice lacking inducible nitric oxide synthase: potential role of tumor necrosis factor-alpha and interleukin-10.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099476

Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099476

Effect of inhibitors of nitric oxide synthase on acetaminophen-induced hepatotoxicity in mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099476

Vascular and hepatocellular peroxynitrite formation during acetaminophen toxicity: role of mitochondrial oxidant stress

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099476

Reperfusion injury in livers due to gentle in situ organ manipulation during harvest involves hypoxia and free radicals.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099476

V. Necrapoptosis and the mitochondrial permeability transition: shared pathways to necrosis and apoptosis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099476

Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker

26 October 2018

1 reference

12 December 2020

Pimonidazole: a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in cervical carcinoma

1 reference

12 December 2020

Vascular endothelial growth factor and hepatocyte regeneration in acetaminophen toxicity

1 reference

12 December 2020

Role of apoptosis in acetaminophen hepatotoxicity

1 reference

12 December 2020

VEGF isoforms and receptors expression throughout acute acetaminophen-induced liver injury and regeneration

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12 December 2020

Expression and role of vascular endothelial growth factor in liver regeneration after partial hepatectomy in rats

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12 December 2020

Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism

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12 December 2020

Centrilobular injury following hypoxia in isolated, perfused rat liver

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12 December 2020

Mechanisms of acetaminophen oxidation to N-acetyl-P-benzoquinone imine by horseradish peroxidase and cytochrome P-450

1 reference

12 December 2020

Glutathione disulfide formation and oxidant stress during acetaminophen-induced hepatotoxicity in mice in vivo: the protective effect of allopurinol

1 reference

12 December 2020

10.1016/J.TAAP.2011.02.005

Identifiers

DOI

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5 August 2017

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5 August 2017

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