(Q34999004)

5 August 2017

title

The E3 ubiquitin ligase Itch controls the protein stability of p63 (English)

1 reference

5 August 2017

1

Mario Rossi

1 reference

5 August 2017

7

Carlo M Croce

1 reference

5 August 2017

Rami I Aqeilan

2

1 reference

5 August 2017

Michael Neale

3

1 reference

5 August 2017

Eleonora Candi

4

1 reference

5 August 2017

Paolo Salomoni

5

1 reference

5 August 2017

Richard A Knight

6

1 reference

5 August 2017

Gerry Melino

8

1 reference

5 August 2017

language of work or name

English

0 references

publication date

14 August 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

published in

1 reference

5 August 2017

volume

103

1 reference

5 August 2017

issue

34

1 reference

5 August 2017

page(s)

12753-12758

1 reference

Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

Negative regulation of the E3 ubiquitin ligase itch via Fyn-mediated tyrosine phosphorylation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

p63 deficiency activates a program of cellular senescence and leads to accelerated aging

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

The ubiquitin-protein ligase Itch regulates p73 stability

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

Functional regulation of p73 and p63: development and cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

p73: Friend or foe in tumorigenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

HIV-based vectors. Preparation and use.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

Mutations in the p53 homolog p63: allele-specific developmental syndromes in humans.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

Association of p63 with proliferative potential in normal and neoplastic human keratinocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

Nedd4-like proteins: an emerging family of ubiquitin-protein ligases implicated in diverse cellular functions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

p63 is a p53 homologue required for limb and epidermal morphogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

Polyomavirus large T antigen induces alterations in cytoplasmic signalling pathways involving Shc activation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550770

Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation.

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0603449103

Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0603449103

Characterization of keratinocyte differentiation induced by ascorbic acid: protein kinase C involvement and vitamin C homeostasis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0603449103

Gain-of-function mutation in ADULT syndrome reveals the presence of a second transactivation domain in p63

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16908849

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of transglutaminase 5 in normal and pathologic human epidermis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16908849

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Itch E3 ligase-mediated regulation of TGF-beta signaling by modulating smad2 phosphorylation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16908849

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0603449103

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference