(Q34999009)

5 August 2017

title

Redesigning dehalogenase access tunnels as a strategy for degrading an anthropogenic substrate (English)

1 reference

5 August 2017

6

Michal Otyepka

0 references

Martin Klvana

Martin Klvana

2

0 references

Zbyněk Prokop

Zbynek Prokop

3

0 references

Radka Chaloupkova

Radka Chaloupkova

4

0 references

Jiří Damborský

Jiri Damborsky

10

0 references

Rebecca C Wade

Rebecca C Wade

7

0 references

Yuji Nagata

9

Yuji Nagata

1 reference

5 August 2017

8

Masataka Tsuda

1 reference

5 August 2017

Martina Pavlova

1

1 reference

5 August 2017

Pavel Banas

5

1 reference

5 August 2017

publication date

23 August 2009

1 reference

5 August 2017

published in

Nature Chemical Biology

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5 August 2017

volume

5

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5 August 2017

issue

10

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5 August 2017

page(s)

727-733

1 reference

https://scigraph.springernature.com/pub.10.1038/nchembio.205

5 August 2017

exact match

0 references

cites work

Purification and properties of haloalkane dehalogenase from Corynebacterium sp. strain m15-3

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.205

The ins and outs of cytochrome P450s.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.205

Crystal structure of the haloalkane dehalogenase from Sphingomonas paucimobilis UT26

21 January 2018

2 references

12 December 2020

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.205

7 January 2021

inferred from DOI database lookup

Purification and characterization of a bacterial dehalogenase with activity toward halogenated alkanes, alcohols and ethers

1 reference

12 December 2020

Haloalkane dehalogenases: structure of a Rhodococcus enzyme

1 reference

12 December 2020

Engineering delta 9-16:0-acyl carrier protein (ACP) desaturase specificity based on combinatorial saturation mutagenesis and logical redesign of the castor delta 9-18:0-ACP desaturase

1 reference

12 December 2020

Chemical and biochemical strategies for the randomization of protein encoding DNA sequences: library construction methods for directed evolution

1 reference

12 December 2020

Protein engineering of toluene monooxygenases for synthesis of chiral sulfoxides

1 reference

12 December 2020

Modification of activity and specificity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26 by engineering of its entrance tunnel.

1 reference

12 December 2020

Steady-state and pre-steady-state kinetic analysis of halopropane conversion by a rhodococcus haloalkane dehalogenase

1 reference

12 December 2020

Cloning of an epoxide hydrolase-encoding gene from Aspergillus niger M200, overexpression in E. coli, and modification of activity and enantioselectivity of the enzyme by protein engineering.

1 reference

12 December 2020

Structure determinants of substrate specificity of hydroxynitrile lyase from Manihot esculenta

1 reference

12 December 2020

Protein engineering of Bacillus megaterium CYP102. The oxidation of polycyclic aromatic hydrocarbons

1 reference

12 December 2020

Solute solvent dynamics and energetics in enzyme catalysis: the S(N)2 reaction of dehalogenase as a general benchmark.

1 reference

12 December 2020

Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase

1 reference

12 December 2020

Degradation of 1,3-dichloropropene by pseudomonas cichorii 170.

1 reference

12 December 2020

Structures of nitric oxide synthase isoforms complexed with the inhibitor AR-R17477 suggest a rational basis for specificity and inhibitor design

1 reference

12 December 2020

Blocking the tunnel: engineering of Candida rugosa lipase mutants with short chain length specificity

1 reference

12 December 2020

Complete Inversion of Enantioselectivity towards Acetylated Tertiary Alcohols by a Double Mutant of aBacillus Subtilis Esterase

1 reference

12 December 2020

The plasmid-located haloalkane dehalogenase gene from Rhodococcus rhodochrous NCIMB 13064.

1 reference

12 December 2020

Improving catalytic function by ProSAR-driven enzyme evolution

1 reference

12 December 2020

Dehalogenases applied to industrial-scale biocatalysis

1 reference

12 December 2020

Catalytic mechanism of the maloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26.

1 reference

12 December 2020

Kemp elimination catalysts by computational enzyme design

1 reference

12 December 2020

Combined QM/MM study of the mechanism and kinetic isotope effect of the nucleophilic substitution reaction in haloalkane dehalogenase

1 reference

12 December 2020

Directed evolution of enantioselective enzymes: iterative cycles of CASTing for probing protein-sequence space

1 reference

12 December 2020

Biodegradation of 1,2,3-trichloropropane through directed evolution and heterologous expression of a haloalkane dehalogenase gene

1 reference

12 December 2020

Comparison of the dynamics of substrate access channels in three cytochrome P450s reveals different opening mechanisms and a novel functional role for a buried arginine

1 reference

12 December 2020

CAVER: a new tool to explore routes from protein clefts, pockets and cavities

1 reference

12 December 2020

Isolation and characterization of a haloalkane halidohydrolase from Rhodococcus erythropolis Y2

1 reference

12 December 2020

Redesigning the substrate specificity of an enzyme: isocitrate dehydrogenase

1 reference

12 December 2020

Protein engineering of toluene 4-monooxygenase of Pseudomonas mendocina KR1 for synthesizing 4-nitrocatechol from nitrobenzene

1 reference

12 December 2020

Mechanism of enhanced conversion of 1,2,3-trichloropropane by mutant haloalkane dehalogenase revealed by molecular modeling.

1 reference

12 December 2020

HotSpot Wizard: a web server for identification of hot spots in protein engineering.

1 reference

12 December 2020

The 'evolvability' of promiscuous protein functions

1 reference

12 December 2020

Comparison of formation of reactive conformers for the SN2 displacements by CH3CO2- in water and by Asp124-CO2- in a haloalkane dehalogenase

1 reference

12 December 2020

Experiences of a large-scale application of 1,2-dichloroethane degrading microorganisms for groundwater treatment

1 reference

12 December 2020

Bacterial degradation of xenobiotic compounds: evolution and distribution of novel enzyme activities

1 reference

12 December 2020

Do mammalian cytochrome P450s show multiple ligand access pathways and ligand channelling?

1 reference

12 December 2020

Utilization of trihalogenated propanes by Agrobacterium radiobacter AD1 through heterologous expression of the haloalkane dehalogenase from Rhodococcus sp. strain M15-3.

1 reference

12 December 2020

Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli

1 reference

12 December 2020

Phylogenetic analysis of haloalkane dehalogenases.

1 reference

12 December 2020

Functionally relevant motions of haloalkane dehalogenases occur in the specificity-modulating cap domains

1 reference

12 December 2020

Improving enzyme properties: when are closer mutations better?

1 reference

12 December 2020

Novel enzymes through design and evolution.

1 reference

12 December 2020

Molecular mechanisms of genetic adaptation to xenobiotic compounds

1 reference

12 December 2020

Kinetics of halide release of haloalkane dehalogenase: evidence for a slow conformational change.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCHEMBIO.205

1 reference

Dimensions Publication ID

5 August 2017

1049357599

0 references

1 reference