(Q35000264)

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Cigarette smoke extract induces COX-2 expression via a PKCalpha/c-Src/EGFR, PDGFR/PI3K/Akt/NF-kappaB pathway and p300 in tracheal smooth muscle cells.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19717552%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Cigarette smoke extract induces COX-2 expression via a PKCalpha/c-Src/EGFR, PDGFR/PI3K/Akt/NF-kappaB pathway and p300 in tracheal smooth muscle cells (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19717552%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

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6 February 2020

author name string

Chuen-Mao Yang

1

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6 February 2020

I-Ta Lee

2

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6 February 2020

Chih-Chung Lin

3

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6 February 2020

Ya-Lin Yang

4

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6 February 2020

Shue-Fen Luo

5

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6 February 2020

Li-Der Hsiao

7

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6 February 2020

publication date

28 August 2009

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6 February 2020

American Journal of Physiology - Lung Cellular and Molecular Physiology

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6 February 2020

297

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6 February 2020

5

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6 February 2020

L892-902

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6 February 2020

Role of translocation in the activation and function of protein kinase B

1 reference

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Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade

1 reference

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The NF-kappa B and I kappa B proteins: new discoveries and insights

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Cyclooxygenase enzymes in allergic inflammation and asthma

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Induction of cyclooxygenase-2 overexpression in human gastric epithelial cells by Helicobacter pylori involves TLR2/TLR9 and c-Src-dependent nuclear factor-kappaB activation.

1 reference

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21 January 2018

Cigarette smoke extract induces cytosolic phospholipase A2 expression via NADPH oxidase, MAPKs, AP-1, and NF-kappaB in human tracheal smooth muscle cells

1 reference

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21 January 2018

Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention

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21 January 2018

Lung disease and PKCs

1 reference

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21 January 2018

Role of p300 and PCAF in regulating cyclooxygenase-2 promoter activation by inflammatory mediators

1 reference

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21 January 2018

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

1 reference

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CREB-binding protein/p300 are transcriptional coactivators of p65

1 reference

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Lysophosphatidic acid-induced transactivation of epidermal growth factor receptor regulates cyclo-oxygenase-2 expression and prostaglandin E(2) release via C/EBPbeta in human bronchial epithelial cells

1 reference

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21 January 2018

Proliferative aspects of airway smooth muscle.

1 reference

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21 January 2018

Synthetic responses in airway smooth muscle

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21 January 2018

Sphingosine-1-phosphate induces COX-2 expression via PI3K/Akt and p42/p44 MAPK pathways in rat vascular smooth muscle cells

1 reference

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21 January 2018

Therapeutic potential of phosphatidylinositol 3-kinase inhibitors in inflammatory respiratory disease.

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21 January 2018

Induction of COX-2 in human airway cells by manganese: role of PI3K/PKB, p38 MAPK, PKCs, Src, and glutathione depletion

1 reference

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21 January 2018

Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells

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21 January 2018

AP-1 function and regulation

1 reference

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21 January 2018

The role of PI3K in immune cells

1 reference

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21 January 2018

Lipoteichoic acid-stimulated p42/p44 MAPK activation via Toll-like receptor 2 in tracheal smooth muscle cells

1 reference

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21 January 2018

Transcriptional regulation of VCAM-1 expression by tumor necrosis factor-alpha in human tracheal smooth muscle cells: involvement of MAPKs, NF-kappaB, p300, and histone acetylation

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21 January 2018

NF-kappaB in cancer: a marked target

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Regulation of tyrosine kinase cascades by G-protein-coupled receptors.

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21 January 2018

The aryl hydrocarbon receptor is a regulator of cigarette smoke induction of the cyclooxygenase and prostaglandin pathways in human lung fibroblasts

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21 January 2018

alpha,beta-Unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases.

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21 January 2018

Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study

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Legionella pneumophila-induced PKCalpha-, MAPK-, and NF-kappaB-dependent COX-2 expression in human lung epithelium.

1 reference

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21 January 2018

Cigarette smoke condensate increases cathepsin-mediated invasiveness of oral carcinoma cells

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Src protein tyrosine kinase family and acute inflammatory responses.

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Protein kinase C alpha and zeta differentially regulate death-inducing signaling complex formation in cigarette smoke extract-induced apoptosis

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Acrolein induces cyclooxygenase-2 and prostaglandin production in human umbilical vein endothelial cells: roles of p38 MAP kinase.

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21 January 2018

Oxidative stress and redox regulation of lung inflammation in COPD.

1 reference

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21 January 2018

Induction of apoptosis with tobacco smoke and related products in A549 lung epithelial cells in vitro.

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21 January 2018

Src kinase regulation by phosphorylation and dephosphorylation

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Thrombocytes respond to lipopolysaccharide through Toll-like receptor-4, and MAP kinase and NF-kappaB pathways leading to expression of interleukin-6 and cyclooxygenase-2 with production of prostaglandin E2.

1 reference

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21 January 2018

The protein kinase C inhibitor Go6976 [12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole] potentiates agonist-induced mitogen-activated protein kinase activation through tyrosine phosphorylation of the e

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Lung carcinogenesis: pivotal role of metals in tobacco smoke

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LY294002 inhibits glucocorticoid-induced COX-2 gene expression in cardiomyocytes through a phosphatidylinositol 3 kinase-independent mechanism

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Lipid-soluble components in cigarette smoke induce mitochondrial production of reactive oxygen species in lung epithelial cells

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Nicotine and oxidative cigarette smoke constituents induce immune-modulatory and pro-inflammatory dendritic cell responses

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p38 and EGF receptor kinase-mediated activation of the phosphatidylinositol 3-kinase/Akt pathway is required for Zn2+-induced cyclooxygenase-2 expression.

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21 January 2018

EGFR activation results in enhanced cyclooxygenase-2 expression through p38 mitogen-activated protein kinase-dependent activation of the Sp1/Sp3 transcription factors in human gliomas

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21 January 2018

Interleukin-1beta-induced cyclooxygenase-2 expression is mediated through activation of p42/44 and p38 MAPKS, and NF-kappaB pathways in canine tracheal smooth muscle cells

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Bradykinin-induced p42/p44 MAPK phosphorylation and cell proliferation via Src, EGF receptors, and PI3-K/Akt in vascular smooth muscle cells

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