(Q35000871)

English

Kaposi's sarcoma-associated herpesvirus-induced upregulation of the c-kit proto-oncogene, as identified by gene expression profiling, is essential for the transformation of endothelial cells

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Europe PubMed Central

PubMed publication ID

5 August 2017

Kaposi's sarcoma-associated herpesvirus-induced upregulation of the c-kit proto-oncogene, as identified by gene expression profiling, is essential for the transformation of endothelial cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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Michael A. Jarvis

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Michael A Jarvis

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Michael C. Heinrich

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Michael C Heinrich

10

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Brian J Druker

9

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author name string

Ashlee V Moses

1

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Europe PubMed Central

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5 August 2017

Camilo Raggo

3

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5 August 2017

Yolanda C Bell

4

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Europe PubMed Central

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5 August 2017

Rebecca Ruhl

5

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Europe PubMed Central

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5 August 2017

B G Mattias Luukkonen

6

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Europe PubMed Central

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5 August 2017

Diana J Griffith

7

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Europe PubMed Central

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5 August 2017

Cecily L Wait

8

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Europe PubMed Central

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5 August 2017

Jay A Nelson

11

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Europe PubMed Central

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5 August 2017

Klaus Früh

12

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5 August 2017

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publication date

1 August 2002

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Europe PubMed Central

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5 August 2017

Journal of Virology

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5 August 2017

76

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Europe PubMed Central

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5 August 2017

16

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Europe PubMed Central

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5 August 2017

8383-8399

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Europe PubMed Central

PubMed publication ID

5 August 2017

Altered patterns of cellular gene expression in dermal microvascular endothelial cells infected with Kaposi's sarcoma-associated herpesvirus

1 reference

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8 July 2018

De novo infection and serial transmission of Kaposi's sarcoma-associated herpesvirus in cultured endothelial cells

1 reference

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8 July 2018

Global gene expression analysis of gastric cancer by oligonucleotide microarrays.

1 reference

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8 July 2018

Gene expression analysis in aggressive NHL.

1 reference

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8 July 2018

Insulin-like growth factor-binding protein 2 in tumorigenesis: protector or promoter?

1 reference

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8 July 2018

Multiclass cancer diagnosis using tumor gene expression signatures

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8 July 2018

Gene expression microarray analysis in cancer biology, pharmacology, and drug development: progress and potential.

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8 July 2018

New mechanisms and pathways for monocyte recruitment

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8 July 2018

Identification of tumor markers in models of human colorectal cancer using a 19,200-element complementary DNA microarray

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8 July 2018

Human herpesvirus 8 (HHV-8)-encoded cytokines induce expression of and autocrine signaling by vascular endothelial growth factor (VEGF) in HHV-8-infected primary-effusion lymphoma cell lines and mediate VEGF-independent antiapoptotic effects

1 reference

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8 July 2018

CD36: a class B scavenger receptor involved in angiogenesis, atherosclerosis, inflammation, and lipid metabolism

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8 July 2018

Peroxisome proliferator-activated receptor-gamma: from adipogenesis to carcinogenesis

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8 July 2018

Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B.

1 reference

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8 July 2018

Spindle cell conversion by Kaposi's sarcoma-associated herpesvirus: formation of colonies and plaques with mixed lytic and latent gene expression in infected primary dermal microvascular endothelial cell cultures

1 reference

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8 July 2018

Phagocytosis and clearance of apoptotic cells is mediated by MER.

1 reference

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8 July 2018

Induction of plasminogen activator inhibitor 1 gene expression in adipocytes by thiazolidinediones.

1 reference

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8 July 2018

Transcription program of human herpesvirus 8 (kaposi's sarcoma-associated herpesvirus).

1 reference

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8 July 2018

Insulin and cancer (Review).

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8 July 2018

Multiple roles for Cdc42 in cell regulation

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8 July 2018

Activation of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) lytic replication by human cytomegalovirus

1 reference

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8 July 2018

Kaposi's sarcoma-associated herpesvirus latent and lytic gene expression as revealed by DNA arrays

1 reference

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8 July 2018

Modulation of cellular and viral gene expression by the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus

1 reference

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8 July 2018

Comparative analysis of the transforming mechanisms of Epstein-Barr virus, Kaposi's sarcoma-associated herpesvirus, and Herpesvirus saimiri

1 reference

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8 July 2018

The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha

1 reference

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8 July 2018

The selective tyrosine kinase inhibitor STI571 inhibits small cell lung cancer growth

1 reference

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8 July 2018

Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor.

1 reference

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8 July 2018

Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31.

1 reference

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8 July 2018

KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors

1 reference

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8 July 2018

Role of insulin-like growth factors and their binding proteins in growth control and carcinogenesis

1 reference

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8 July 2018

c-Kit and c-kit mutations in mastocytosis and other hematological diseases.

1 reference

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8 July 2018

The insulin-like growth factor axis: A review of atherosclerosis and restenosis

1 reference

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8 July 2018

The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice

1 reference

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8 July 2018

Early signaling pathways activated by c-Kit in hematopoietic cells

1 reference

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8 July 2018

Long-term infection and transformation of dermal microvascular endothelial cells by human herpesvirus 8.

1 reference

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8 July 2018

Activating c-kit gene mutations in human germ cell tumors

1 reference

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8 July 2018

Angiogenesis and hematopoiesis induced by Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6.

1 reference

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8 July 2018

Human herpesvirus 8-encoded thymidine kinase and phosphotransferase homologues confer sensitivity to ganciclovir

1 reference

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8 July 2018

Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma

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8 July 2018

Cellular tropism and viral interleukin-6 expression distinguish human herpesvirus 8 involvement in Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

8 July 2018

Kaposi's sarcoma pathogenesis: a link between immunology and tumor biology

1 reference

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8 July 2018

Kinetics of Kaposi's sarcoma-associated herpesvirus gene expression

1 reference

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8 July 2018

Human herpesvirus-8 ORF K8.1 gene encodes immunogenic glycoproteins generated by spliced transcripts

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8 July 2018

Familial gastrointestinal stromal tumours with germline mutation of the KIT gene

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8 July 2018

Limited transmission of Kaposi's sarcoma-associated herpesvirus in cultured cells

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8 July 2018

Identification of kaposin (open reading frame K12) as a human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus) transforming gene

1 reference

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8 July 2018

PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL

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8 July 2018

Establishing a KSHV+ cell line (BCP-1) from peripheral blood and characterizing its growth in Nod/SCID mice

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8 July 2018

Transformation of NIH3T3 fibroblasts by the c-Kit receptor tyrosine kinase: effect of receptor density and ligand-requirement

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8 July 2018

Identification and characterization of human herpesvirus-8 lytic cycle-associated ORF 59 protein and the encoding cDNA by monoclonal antibody

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8 July 2018

Transcription mapping of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) genome in a body cavity-based lymphoma cell line (BC-1)

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8 July 2018

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

1 reference

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8 July 2018

G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

1 reference

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8 July 2018

Expression of human herpesvirus 8-encoded cyclin D in Kaposi's sarcoma spindle cells

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8 July 2018

Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins.

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8 July 2018

KSHV ORF K9 (vIRF) is an oncogene which inhibits the interferon signaling pathway

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8 July 2018

Angiogenic and HIV-inhibitory functions of KSHV-encoded chemokines

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8 July 2018

The 222- to 234-kilodalton latent nuclear protein (LNA) of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) is encoded by orf73 and is a component of the latency-associated nuclear antigen

1 reference

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8 July 2018

Expression of HHV-8 latency-associated T0.7 RNA in spindle cells and endothelial cells of AIDS-associated, classical and African Kaposi's sarcoma

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8 July 2018

Insulin and insulin-like growth factor 1 antagonize the stimulation of ob gene expression by dexamethasone in cultured rat adipose tissue

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8 July 2018

Characterization of a chemokine receptor-related gene in human herpesvirus 8 and its expression in Kaposi's sarcoma

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8 July 2018

Neuritin: a gene induced by neural activity and neurotrophins that promotes neuritogenesis

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8 July 2018

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

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8 July 2018

A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak

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8 July 2018

Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cells

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8 July 2018

Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV.

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8 July 2018

Kaposi's sarcoma-associated herpesvirus contains G protein-coupled receptor and cyclin D homologs which are expressed in Kaposi's sarcoma and malignant lymphoma

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8 July 2018

The size and conformation of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) DNA in infected cells and virions

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8 July 2018

Establishment and characterization of a primary effusion (body cavity-based) lymphoma cell line (BC-3) harboring kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in the absence of Epstein-Barr virus.

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8 July 2018

Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma

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8 July 2018

Cyclin encoded by KS herpesvirus

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8 July 2018

Localization of human herpes-like virus type 8 in vascular endothelial cells and perivascular spindle-shaped cells of Kaposi's sarcoma lesions by in situ hybridization

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8 July 2018

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

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8 July 2018

Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative.

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8 July 2018

Autocrine growth of small cell lung cancer mediated by coexpression of c-kit and stem cell factor.

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8 July 2018

Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

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8 July 2018

RETRACTED: Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class

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8 July 2018

Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas

1 reference

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8 July 2018

Constitutive expression of steel factor gene by human stromal cells.

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8 July 2018

Expression of the c-kit protein in human solid tumors and in corresponding fetal and adult normal tissues.

1 reference

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8 July 2018

Coexpression of the c-kit and stem cell factor genes in breast carcinomas.

1 reference

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8 July 2018

Coordinate regulation of Steel factor, its receptor (Kit), and cytoadhesion molecule (ICAM-1 and ELAM-1) mRNA expression in human vascular endothelial cells of differing origins

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8 July 2018

The expression of endothelial cell surface antigens by AIDS-associated Kaposi's sarcoma. Evidence for a vascular endothelial cell origin

1 reference

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8 July 2018

AIDS-related Kaposi's sarcoma displays differential expression of endothelial surface antigens

1 reference

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8 July 2018

Evidence for the origin of Kaposi's sarcoma from lymphatic endothelium

1 reference

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8 July 2018

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand

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8 July 2018

Primary structure and functional expression of rat and human stem cell factor DNAs

1 reference

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8 July 2018

An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT.

1 reference

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8 July 2018

Expression of functional c-kit receptors rescues the genetic defect of W mutant mast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

8 July 2018

Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

8 July 2018

Receptor functions and ligand-dependent transforming potential of a chimeric kit proto-oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

8 July 2018

Nonhematopoietic tumor cell lines express stem cell factor and display c-kit receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

8 July 2018

Expression of stem cell factor and c-kit mRNA in cultured endothelial cells, monocytes and cloned human bone marrow stromal cells (CFU-RF)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

8 July 2018

Gastrointestinal stromal tumors with KIT mutations exhibit a remarkably homogeneous gene expression profile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

26 October 2018

Virogenomics: a novel approach to antiviral drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

26 October 2018

The human cytomegalovirus chemokine receptor US28 mediates vascular smooth muscle cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

26 October 2018

Organization of the chemokine gene cluster on human chromosome 17q11.2 containing the genes for CC chemokine MPIF-1, HCC-2, HCC-1, LEC, and RANTES.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

26 October 2018

Novel organizational features, captured cellular genes, and strain variability within the genome of KSHV/HHV8.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

26 October 2018

Transformation of primary human endothelial cells by Kaposi's sarcoma-associated herpesvirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

26 October 2018

Cloning and developmental expression analysis of the murine c-mer tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

26 October 2018

Herpes-like sequences in HIV-infected and uninfected Kaposi's sarcoma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

26 October 2018

Coexpression of the c-kit receptor and the stem cell factor in gynecological tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

26 October 2018

Chromosomal translocations and leukaemia: a role for LMO2 in T cell acute leukaemia, in transcription and in erythropoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155158

26 October 2018

Umbilical vein endothelial cells are an important source of c-kit and stem cell factor which regulate the proliferation of haemopoietic progenitor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12134042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12134042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human umbilical vein endothelial cells display high-affinity c-kit receptors and produce a soluble form of the c-kit receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12134042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of adhesion molecules, platelet-activating factor, and chemokines by Kaposi's sarcoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12134042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571

1 reference

https://pubmed.ncbi.nlm.nih.gov/12134042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cultured, AIDS-related Kaposi's sarcoma cells express endothelial cell markers and are weakly malignant in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/12134042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KIT expression in angiosarcomas and fetal endothelial cells: lack of mutations of exon 11 and exon 17 of C-kit

1 reference

https://pubmed.ncbi.nlm.nih.gov/12134042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular and molecular features of HIV-associated Kaposi's sarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12134042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombospondin-1 inhibits Kaposi's sarcoma (KS) cell and HIV-1 Tat-induced angiogenesis and is poorly expressed in KS lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12134042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retroviral-mediated gene transduction of c-kit into single hematopoietic progenitor cells from cord blood enhances erythroid colony formation and decreases sensitivity to inhibition by tumor necrosis factor-alpha and transforming growth factor-beta1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12134042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular proteolysis and angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12134042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human endothelial cell response to gram-negative lipopolysaccharide assessed with cDNA microarrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/12134042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KSHV sequences in biopsies and cultured spindle cells of epidemic, iatrogenic and Mediterranean forms of Kaposi's sarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12134042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.76.16.8383-8399.2002

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Sitelinks

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