(Q35004298)

5 August 2017

title

ATGL-catalyzed lipolysis regulates SIRT1 to control PGC-1α/PPAR-α signaling (English)

1 reference

5 August 2017

6

Douglas G Mashek

1 reference

5 August 2017

Salmaan Ahmed Khan

1

1 reference

5 August 2017

Aishwarya Sathyanarayan

2

1 reference

5 August 2017

Mara T Mashek

3

1 reference

5 August 2017

Kuok Teong Ong

4

1 reference

5 August 2017

Edith E Wollaston-Hayden

5

1 reference

5 August 2017

language of work or name

English

0 references

publication date

1 February 2015

1 reference

5 August 2017

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

Diabetes

1 reference

5 August 2017

volume

64

1 reference

5 August 2017

issue

2

1 reference

5 August 2017

page(s)

418-426

1 reference

Hepatic ATGL mediates PPAR-α signaling and fatty acid channeling through an L-FABP independent mechanism

5 August 2017

cites work

1 reference

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Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity

8 July 2018

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The protein level of PGC-1α, a key metabolic regulator, is controlled by NADH-NQO1.

8 July 2018

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8 July 2018

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Myocardial adipose triglyceride lipase overexpression protects diabetic mice from the development of lipotoxic cardiomyopathy

8 July 2018

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Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling

8 July 2018

1 reference

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Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply

8 July 2018

1 reference

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Are sirtuins viable targets for improving healthspan and lifespan?

8 July 2018

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Role of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase.

8 July 2018

1 reference

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The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+).

8 July 2018

1 reference

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Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance

8 July 2018

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Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans

8 July 2018

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ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.

8 July 2018

1 reference

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Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype

8 July 2018

1 reference

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The role of lipid droplets in metabolic disease in rodents and humans

8 July 2018

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Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signaling

8 July 2018

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Intracellular fatty acids suppress β-adrenergic induction of PKA-targeted gene expression in white adipocytes

8 July 2018

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Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver

8 July 2018

1 reference

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Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning

8 July 2018

1 reference

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Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress.

8 July 2018

1 reference

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SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity

8 July 2018

1 reference

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Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Hepatic triacylglycerol hydrolysis regulates peroxisome proliferator-activated receptor alpha activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Fat metabolism links germline stem cells and longevity in C. elegans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Adipose triglyceride lipase regulates basal lipolysis and lipid droplet size in adipocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

SirT1 gain of function increases energy efficiency and prevents diabetes in mice

8 July 2018

1 reference

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Sequential changes in the expression of genes involved in lipid metabolism in adipose tissue and liver in response to fasting

8 July 2018

1 reference

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SirT1 regulates energy metabolism and response to caloric restriction in mice

8 July 2018

1 reference

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Negative regulation of the deacetylase SIRT1 by DBC1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

DBC1 is a negative regulator of SIRT1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Regulation of triglyceride metabolism. IV. Hormonal regulation of lipolysis in adipose tissue

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Adipose tissue lipolysis as a metabolic pathway to define pharmacological strategies against obesity and the metabolic syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Adipose triacylglycerol lipase is a major regulator of hepatic lipid metabolism but not insulin sensitivity in mice.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303962

Effect of bezafibrate treatment on late-onset mitochondrial myopathy in mice

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25614670

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2337/DB14-0325

1 reference

5 August 2017

1 reference

5 August 2017

1 reference