(Q35006667)

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Aminothienopyridazine inhibitors of tau aggregation: evaluation of structure-activity relationship leads to selection of candidates with desirable in vivo properties.

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5 February 2020

Aminothienopyridazine inhibitors of tau aggregation: evaluation of structure-activity relationship leads to selection of candidates with desirable in vivo properties (English)

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5 February 2020

Carlo Ballatore

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5 February 2020

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5 February 2020

John Q. Trojanowski

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John Q Trojanowski

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5 February 2020

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Alex Crowe

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5 February 2020

Francesco Piscitelli

3

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5 February 2020

Michael James

4

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5 February 2020

Gabrielle Rossidivito

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5 February 2020

Yuemang Yao

7

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5 February 2020

Virginia M-Y Lee

9

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5 February 2020

Kurt R Brunden

10

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5 February 2020

Amos B Smith

11

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5 February 2020

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23 May 2012

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5 February 2020

Bioorganic & Medicinal Chemistry

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5 February 2020

20

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5 February 2020

14

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5 February 2020

4451-4461

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5 February 2020

Modulation of protein-protein interactions as a therapeutic strategy for the treatment of neurodegenerative tauopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304654

8 July 2018

Discovery of brain-penetrant, orally bioavailable aminothienopyridazine inhibitors of tau aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304654

8 July 2018

Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304654

8 July 2018

Tau-directed drug discovery for Alzheimer's disease and related tauopathies: a focus on tau assembly inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304654

8 July 2018

Identification of aminothienopyridazine inhibitors of tau assembly by quantitative high-throughput screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304654

8 July 2018

2-aminothienopyridazines as novel adenosine A1 receptor allosteric modulators and antagonists.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304654

8 July 2018

Nucleation-dependent tau filament formation: the importance of dimerization and an estimation of elementary rate constants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304654

8 July 2018

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304654

8 July 2018

High throughput screening for small molecule inhibitors of heparin-induced tau fibril formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304654

8 July 2018

Mutations causing neurodegenerative tauopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304654

8 July 2018

In vitro polymerization of tau protein monitored by laser light scattering: method and application to the study of FTDP-17 mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304654

8 July 2018

Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304654

8 July 2018

Syntheses and antiinflammatory actions of 4,5,6,7-tetrahydroindazole-5-carboxylic acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304654

8 July 2018

Domains of tau protein and interactions with microtubules

1 reference

https://pubmed.ncbi.nlm.nih.gov/22717239

12 December 2020

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10.1016/J.BMC.2012.05.027

1 reference

Europe PubMed Central

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5 February 2020

1 reference

Europe PubMed Central

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5 February 2020

1 reference

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5 February 2020

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