(Q35007051)

5 August 2017

title

Model system to define pharmacokinetic requirements for antimalarial drug efficacy (English)

1 reference

5 August 2017

0 references

1 reference

Rahul P Bakshi

1

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author name string

Elizabeth Nenortas

2

1 reference

5 August 2017

Abhai K Tripathi

3

1 reference

5 August 2017

David J Sullivan

4

1 reference

5 August 2017

Theresa A Shapiro

5

1 reference

5 August 2017

language of work or name

English

0 references

publication date

1 October 2013

1 reference

Science Translational Medicine

5 August 2017

published in

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5 August 2017

volume

5

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5 August 2017

issue

205

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5 August 2017

page(s)

205ra135

1 reference

Altered temporal response of malaria parasites determines differential sensitivity to artemisinin

5 August 2017

cites work

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8 July 2018

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8 July 2018

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8 July 2018

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Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Thousands of chemical starting points for antimalarial lead identification

8 July 2018

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8 July 2018

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Artemisinin Resistance in Plasmodium falciparum Malaria

8 July 2018

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Transient potent BCR-ABL inhibition is sufficient to commit chronic myeloid leukemia cells irreversibly to apoptosis

8 July 2018

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A genetically hard-wired metabolic transcriptome in Plasmodium falciparum fails to mount protective responses to lethal antifolates

8 July 2018

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A murine model of falciparum-malaria by in vivo selection of competent strains in non-myelodepleted mice engrafted with human erythrocytes

8 July 2018

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Concentration-dependent Mycobacterium tuberculosis killing and prevention of resistance by rifampin

8 July 2018

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In vitro susceptibility of P. falciparum populations from Colombia and Tanzania to a new synthetic peroxide (OZ277).

8 July 2018

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The pharmacokinetics of intravenous artesunate in adults with severe falciparum malaria

8 July 2018

1 reference

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Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'.

8 July 2018

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8 July 2018

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A new method for culturing Plasmodium falciparum shows replication at the highest erythrocyte densities

8 July 2018

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Genome sequence of the human malaria parasite Plasmodium falciparum

8 July 2018

1 reference

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A comparison of oral artesunate and artemether antimalarial bioactivities in acute falciparum malaria

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845824

Prospective evaluation of the effect of an aminoglycoside dosing regimen on rates of observed nephrotoxicity and ototoxicity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845824

Evaluation of cell-killing effects of 1-beta-D-arabinofuranosylcytosine and daunorubicin by a new computer-controlled in vitro pharmacokinetic simulation system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845824

The malaria parasite supplies glutathione to its host cell--investigation of glutathione transport and metabolism in human erythrocytes infected with Plasmodium falciparum

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845824

Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men.

8 July 2018

1 reference

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Pharmacokinetics of quinine, chloroquine and amodiaquine. Clinical implications

8 July 2018

1 reference

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Clonal viability measurements on Plasmodium falciparum to assess in vitro schizonticidal activity of leupeptin, chloroquine, and 5-fluoroorotate

8 July 2018

1 reference

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Once versus thrice daily gentamicin in patients with serious infections

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845824

Concentration and time dependency of artemisinin efficacy against Plasmodium falciparum in vitro.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845824

Activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl) cytosine against human cytomegalovirus when administered as single-bolus dose and continuous infusion in in vitro cell culture perfusion system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845824

Oxygen- and time-dependent effects of antibiotics and selected mitochondrial inhibitors on Plasmodium falciparum in culture

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845824

Double blind randomised clinical trial of oral artesunate at once or twice daily dose in falciparum malaria

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845824

Human malaria parasites in continuous culture

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845824

Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845824

Plasmodium falciparum: Microaerophilic requirements in human red blood cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845824

Two compartment kinetic model with multiple artificial capillary units

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3006684

Pharmacokinetics of artemisinin and artesunate after oral administration in healthy volunteers.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845824

Susceptibility of Plasmodium falciparum to quinine in vitro: effects of drug concentrations and time of exposure

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24089407

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Oxygen gradients in the microcirculation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24089407

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Antimalarial activity of selected aromatic chelators. II. Substituted quinolines and quinoline-N-oxides

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24089407

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCITRANSLMED.3006684

1 reference

5 August 2017

1 reference

5 August 2017

1 reference