(Q35008122)

5 August 2017

title

A detailed mathematical model predicts that serial engagement of IgE-Fc epsilon RI complexes can enhance Syk activation in mast cells (English)

1 reference

5 August 2017

A Detailed Mathematical Model Predicts That Serial Engagement of IgE–FcεRI Complexes Can Enhance Syk Activation in Mast Cells (English)

1 reference

Crossref

https://api.crossref.org/works/10.4049/JIMMUNOL.1000326

21 June 2024

1 reference

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20733205

21 June 2024

3

Michael L. Blinov

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20733205

21 June 2024

author name string

Ambarish Nag

1

1 reference

5 August 2017

Byron Goldstein

4

1 reference

5 August 2017

Michael I. Monine

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20733205

21 June 2024

language of work or name

English

0 references

publication date

23 August 2010

1 reference

full work available at URL

5 August 2017

https://journals.aai.org/jimmunol/article-pdf/185/6/3268/1332157/1000326.pdf

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20733205

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20733205/?tool=EBI

21 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20733205

http://www.jimmunol.org/cgi/content/abstract/185/6/3268

21 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20733205

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20733205/pdf/?tool=EBI

21 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20733205

https://europepmc.org/articles/PMC3102320

21 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20733205

https://europepmc.org/articles/PMC3102320?pdf=render

21 June 2024

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20733205

https://doi.org/10.4049/jimmunol.1000326

21 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20733205

https://journals.aai.org/jimmunol/article-pdf/185/6/3268/1332157/1000326.pdf

21 June 2024

1 reference

Crossref

https://api.crossref.org/works/10.4049/JIMMUNOL.1000326

21 June 2024

published in

Journal of Immunology

1 reference

5 August 2017

volume

185

1 reference

5 August 2017

issue

6

1 reference

5 August 2017

page(s)

3268-3276

1 reference

Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Small, mobile FcepsilonRI receptor aggregates are signaling competent

8 July 2018

1 reference

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Rule-based modeling of biochemical systems with BioNetGen

8 July 2018

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T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity

8 July 2018

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Kinetic proofreading model.

8 July 2018

1 reference

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Actin restricts FcepsilonRI diffusion and facilitates antigen-induced receptor immobilization

8 July 2018

1 reference

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BioNetGen: software for rule-based modeling of signal transduction based on the interactions of molecular domains

8 July 2018

1 reference

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Cutting Edge: Transmembrane phosphoprotein Csk-binding protein/phosphoprotein associated with glycosphingolipid-enriched microdomains as a negative feedback regulator of mast cell signaling through the FcepsilonRI

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Calculations show substantial serial engagement of T cell receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Detergent-resistant microdomains offer no refuge for proteins phosphorylated by the IgE receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Phosphorylation of Syk activation loop tyrosines is essential for Syk function. An in vivo study using a specific anti-Syk activation loop phosphotyrosine antibody

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Dissociation of HIV-1 from follicular dendritic cells during HAART: mathematical analysis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Mutations in the activation loop tyrosines of protein tyrosine kinase Syk abrogate intracellular signaling but not kinase activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Exploiting the difference between intrinsic and extrinsic kinases: implications for regulation of signaling by immunoreceptors.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Shuttling of initiating kinase between discrete aggregates of the high affinity receptor for IgE regulates the cellular response

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Kinetic proofreading in T-cell receptor signal transduction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Kinetics of tyrosine phosphorylation when IgE dimers bind to FC epsilon receptors on rat basophilic leukemia cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Aggregation of the high-affinity IgE receptor and enhanced activity of p53/56lyn protein-tyrosine kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Dynamics of signal transduction after aggregation of cell-surface receptors: studies on the type I receptor for IgE.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

The interaction of IgE with rat basophilic leukemia cells. II. Quantitative aspects of the binding reaction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Antibody affinity. VII. Multivalent interaction of anti-lactoside antibody.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Cross-linking of receptor-bound IgE to aggregates larger than dimers leads to rapid immobilization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

The half-life of the T-cell receptor/peptide-major histocompatibility complex interaction can modulate T-cell activation in response to bacterial challenge.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Investigation of early events in Fc epsilon RI-mediated signaling using a detailed mathematical model

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

Retention of antigen on follicular dendritic cells and B lymphocytes through complement-mediated multivalent ligand-receptor interactions: theory and application to HIV treatment.

26 October 2018

1 reference

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Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102320

An unusual mechanism for ligand antagonism

26 October 2018

1 reference

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Larger oligomers of IgE are more effective than dimers in stimulating rat basophilic leukemia cells

26 October 2018

1 reference

12 December 2020

Activated TCRs remain marked for internalization after dissociation from pMHC

1 reference

12 December 2020

Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation

1 reference

12 December 2020

Serial engagement proposed

1 reference

12 December 2020

Characterization of protein-tyrosine phosphatases that dephosphorylate the high affinity IgE receptor

1 reference

12 December 2020

Serial TCR engagement and down-modulation by peptide:MHC molecule ligands: relationship to the quality of individual TCR signaling events

1 reference

12 December 2020

From TCR Engagement to T Cell Activation

1 reference

12 December 2020

THE REACTION WITH RED CELLS OF 7S RABBIT ANTIBODY, ITS SUB-UNITS AND THEIR RECOMBINANTS

1 reference

12 December 2020

Antibody affinity—III the role of multivalence

17

1 reference

Crossref

https://api.crossref.org/works/10.4049/JIMMUNOL.1000326

21 June 2024

Identifiers

1 reference

5 August 2017

1 reference

5 August 2017

1 reference