(Q35010965)

5 August 2017

Separation of fast from slow anabolism by site-specific PEGylation of insulin-like growth factor I (IGF-I). (English)

1 reference

5 August 2017

Pierre De Meyts

18

0 references

Andreas Hoeflich

object named as

Andreas Hoeflich

17

0 references

Gordon S. Lynch

object named as

Gordon S Lynch

16

0 references

author name string

Friedrich Metzger

1

1 reference

5 August 2017

Waseem Sajid

2

1 reference

5 August 2017

Stefanie Saenger

3

1 reference

5 August 2017

Christian Staudenmaier

4

1 reference

5 August 2017

Chris van der Poel

5

1 reference

5 August 2017

Bettina Sobottka

6

1 reference

5 August 2017

Angelika Schuler

7

1 reference

5 August 2017

Mandy Sawitzky

8

1 reference

5 August 2017

Raphael Poirier

9

1 reference

5 August 2017

Dietrich Tuerck

10

1 reference

5 August 2017

Eginhard Schick

11

1 reference

5 August 2017

Andreas Schaubmar

12

1 reference

5 August 2017

Friederike Hesse

13

1 reference

5 August 2017

Kurt Amrein

14

1 reference

5 August 2017

Hansruedi Loetscher

15

1 reference

5 August 2017

Hans-Joachim Schoenfeld

19

1 reference

5 August 2017

language of work or name

English

0 references

publication date

1 April 2011

1 reference

Journal of Biological Chemistry

5 August 2017

1 reference

5 August 2017

286

1 reference

5 August 2017

22

1 reference

5 August 2017

19501-19510

1 reference

PEGylation of therapeutic proteins

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Structural basis of allosteric ligand-receptor interactions in the insulin/relaxin peptide family: implications for other receptor tyrosine kinases and G-protein-coupled receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Harmonic oscillator model of the insulin and IGF1 receptors' allosteric binding and activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

PEGylation: an approach for drug delivery. A review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Insulin-like growth factor I (IGF-I) is a more potent regulator of gene expression than insulin in primary human myoblasts and myotubes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Recombinant human insulin-like growth factor-1: a new cardiovascular disease treatment option?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Alanine scanning of a putative receptor binding surface of insulin-like growth factor-I

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Mecasermin rinfabate: rhIGF-I/rhIGFBP-3 complex: iPLEX

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Contrasting bone effects of temporary versus permanent IGFBP administration in rodents

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Type I insulin-like growth factor receptor signaling in skeletal muscle regeneration and hypertrophy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

IGF-binding protein-2 protects against the development of obesity and insulin resistance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Structure of the insulin receptor ectodomain reveals a folded-over conformation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Molecular interactions of the IGF system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Insulin-like growth factor-I treatment of growth disorders, diabetes mellitus and insulin resistance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Development of a long-acting insulin analog using albumin fusion technology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Insulin-like growth factor (IGF)-binding protein-4 inhibits colony formation of colorectal cancer cells by IGF-independent mechanisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Insulin-like growth factor-1 and post-ischemic brain injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Effect of pegylation on pharmaceuticals

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Signalling pathways that mediate skeletal muscle hypertrophy and atrophy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Cellular actions of the insulin-like growth factor binding proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Improved contractile function of the mdx dystrophic mouse diaphragm muscle after insulin-like growth factor-I administration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Structural biology of insulin and IGF1 receptors: implications for drug design

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

IGF-1 receptor as an alternative receptor for metabolic signaling in insulin receptor-deficient muscle cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Normal growth and development in the absence of hepatic insulin-like growth factor I

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Positively charged side chains in the insulin-like growth factor-1 C- and D-regions determine receptor binding specificity.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Insulin-like growth factor 1 supports embryonic nerve cell survival

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Receptor Binding and Tyrosine Kinase Activation by Insulin Analogues With Extreme Affinities Studied in Human Hepatoma HepG2 Cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

Expression of a type I insulin-like growth factor receptor with low affinity for insulin-like growth factor II

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

An established preadipose cell line and its differentiation in culture II. Factors affecting the adipose conversion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

The combination of insulin-like growth factor I and insulin-like growth factor-binding protein-3 reduces insulin requirements in insulin-dependent type 1 diabetes: evidence for in vivo biological activity.

8 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172189

Dose-dependent effects of recombinant human insulin-like growth factor (IGF)-I/IGF binding protein-3 complex on overnight growth hormone secretion and insulin sensitivity in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172189

Structural basis of the aberrant receptor binding properties of hagfish and lamprey insulins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172189

Overexpression of insulin-like growth factor-binding protein-2 in transgenic mice reduces postnatal body weight gain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172189

Model for the complex between the insulin-like growth factor I and its receptor: towards designing antagonists for the IGF-1 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172189

All-atom structural models for complexes of insulin-like growth factors IGF1 and IGF2 with their cognate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172189

Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and the insulin-like growth factors I and II.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103329

The relationship between overnight GH levels and insulin concentrations in adolescents with insulin-dependent diabetes mellitus (IDDM) and the impact of recombinant human insulin-like growth factor I (rhIGF-I)

25 October 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172189

The C region of human insulin-like growth factor (IGF) I is required for high affinity binding to the type 1 IGF receptor.

21 January 2018

1 reference

12 December 2020

The molecular basis of muscular dystrophy in the mdx mouse: a point mutation

1 reference

12 December 2020

Hormonal and metabolic effects and pharmacokinetics of recombinant insulin-like growth factor-I in growth hormone receptor deficiency/Laron syndrome

1 reference

12 December 2020

Overexpression of the human type-1 insulin-like growth factor receptor in rat L6 myoblasts induces ligand-dependent cell proliferation and inhibition of differentiation

1 reference

12 December 2020

Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice

1 reference

12 December 2020

Role of insulin-like growth factor binding proteins in controlling IGF actions

1 reference

12 December 2020

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

1 reference

12 December 2020

Systemic administration of IGF-I enhances oxidative status and reduces contraction-induced injury in skeletal muscles of mdx dystrophic mice

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.172189

1 reference

5 August 2017

1 reference

5 August 2017

1 reference