(Q35011880)

5 August 2017

1 reference

title

Histone deacetylase inhibitors: from target to clinical trials (English)

1 reference

5 August 2017

William K Kelly

1

1 reference

5 August 2017

Owen A O'Connor

series ordinal

2

1 reference

5 August 2017

Paul A Marks

series ordinal

3

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5 August 2017

language of work or name

English

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publication date

1 December 2002

1 reference

Expert Opinion on Investigational Drugs

5 August 2017

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5 August 2017

11

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5 August 2017

12

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5 August 2017

1695-1713

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Erythroleukemic Differentiation

5 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Histone deacetylases and cancer: causes and therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Translating the Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Signaling to chromatin through histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Deviant nucleosomes: the functional specialization of chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

The language of covalent histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Functional significance of histone deacetylase diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Histone deacetylases: silencers for hire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Histone acetylation and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Histone deacetylases, transcriptional control, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Histone acetylation and the cell-cycle in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Histone deacetylase inhibitors in cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Worms gang up on bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Core-binding factors in haematopoiesis and leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Genes modulated by histone acetylation as new effectors of butyrate activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Histone acetylation and chromatin remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Covalent modifications of histones: expression from chromatin templates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Molecular biology. Methylation talk between histones and DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Acetylation of histones and transcription-related factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Histone acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

The human histone deacetylase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Three proteins define a class of human histone deacetylases related to yeast Hda1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Isolation and characterization of mammalian HDAC10, a novel histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Molecular cloning and characterization of a novel histone deacetylase HDAC10

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Human class I histone deacetylase complexes show enhanced catalytic activity in the presence of ATP and co-immunoprecipitate with the ATP-dependent chaperone protein Hsp70

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Genomewide studies of histone deacetylase function in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Association of histone deacetylase with COUP-TF in tumorigenic Ad12-transformed cells and its potential role in shut-off of MHC class I transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Conjunction dysfunction: CBP/p300 in human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Defect of histone acetyltransferase activity of the nuclear transcriptional coactivator CBP in Rubinstein-Taybi syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

BRCA1 interacts with components of the histone deacetylase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Histone deacetylase as a therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Histone deacetylase inhibitors as new cancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Novel histone deacetylase inhibitors: N-hydroxycarboxamides possessing a terminal bicyclic aryl group

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Butyrate as a differentiating agent: pharmacokinetics, analogues and current status

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Modifying histones to tame cancer: clinical development of sodium phenylbutyrate and other histone deacetylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Anti-tumour activity in vitro and in vivo of selective differentiating agents containing hydroxamate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Tumor selectivity and transcriptional activation by azelaic bishydroxamic acid in human melanocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

In vivo effects of a histone deacetylase inhibitor, FK228, on human acute promyelocytic leukemia in NOD / Shi-scid/scid mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Phase II study of phenylacetate in patients with recurrent malignant glioma: a North American Brain Tumor Consortium report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in v

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Chronic oral administration of CI-994: a phase 1 study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Oxamflatin is a novel antitumor compound that inhibits mammalian histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

Mutations truncating the EP300 acetylase in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1695

10.1517/13543784.11.12.1695

21 January 2018

Identifiers

DOI

1 reference

5 August 2017

1 reference