(Q35012024)

5 August 2017

title

Recent advances in inflammatory bowel disease: mucosal immune cells in intestinal inflammation (English)

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inflammatory bowel diseases

5 August 2017

main subject

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2

Arthur Kaser

1 reference

5 August 2017

M Zaeem Cader

1

1 reference

5 August 2017

language of work or name

English

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publication date

1 November 2013

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5 August 2017

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5 August 2017

volume

62

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5 August 2017

issue

11

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5 August 2017

page(s)

1653-1664

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Intestinal homeostasis and its breakdown in inflammatory bowel disease

5 August 2017

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The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses

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RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

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Gut immune maturation depends on colonization with a host-specific microbiota

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Diversity, stability and resilience of the human gut microbiota

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The effect of infections on susceptibility to autoimmune and allergic diseases

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Regulatory T cells and Foxp3

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Induction of colonic regulatory T cells by indigenous Clostridium species

21 January 2018

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Probiotics ameliorate recurrent Th1-mediated murine colitis by inducing IL-10 and IL-10-dependent TGF-beta-bearing regulatory cells

21 January 2018

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Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases

21 January 2018

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Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

21 January 2018

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Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation

21 January 2018

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Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles

21 January 2018

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ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

21 January 2018

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Dietary influences on intestinal immunity

21 January 2018

1 reference

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Stem cells, self-renewal, and differentiation in the intestinal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Composition and functional role of the mucus layers in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions

21 January 2018

1 reference

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Glycan foraging in vivo by an intestine-adapted bacterial symbiont

21 January 2018

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The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine

21 January 2018

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Altered mucin expression in the gastrointestinal tract: a review

21 January 2018

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21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection

21 January 2018

1 reference

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Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Bacterial colonization leads to the colonic secretion of RELMβ/FIZZ2, a novel goblet cell-specific protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Intestinal epithelial cell secretion of RELM-beta protects against gastrointestinal worm infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Crohn's disease and the NOD2 gene: a role for paneth cells

21 January 2018

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https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Intracellular NOD-like receptors in host defense and disease

21 January 2018

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https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Crohn's disease: NOD2, autophagy and ER stress converge

21 January 2018

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Reduced Paneth cell alpha-defensins in ileal Crohn's disease

21 January 2018

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Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

21 January 2018

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Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum

21 January 2018

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A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

21 January 2018

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Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

21 January 2018

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Autophagy in the Pathogenesis of Disease

21 January 2018

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A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

21 January 2018

1 reference

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Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

21 January 2018

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Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production

21 January 2018

1 reference

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Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Autophagy, microbial sensing, endoplasmic reticulum stress, and epithelial function in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Evaluation of AGR2 and AGR3 as candidate genes for inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Altered endoplasmic reticulum stress affects translation in inactive colon tissue from patients with ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Unravelling mononuclear phagocyte heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Blood monocytes: distinct subsets, how they relate to dendritic cells, and their possible roles in the regulation of T-cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Enteric flora expands gut lamina propria CX3CR1+ dendritic cells supporting inflammatory immune responses under normal and inflammatory conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Intestinal macrophages lack CD14 and CD89 and consequently are down-regulated for LPS- and IgA-mediated activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Biological therapies for inflammatory bowel diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Essential role for CD103 in the T cell-mediated regulation of experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

E-cadherin marks a subset of inflammatory dendritic cells that promote T cell-mediated colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Innate lymphoid cells--a proposal for uniform nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Innate lymphoid cells--how did we miss them?

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Innate lymphoid cells: emerging insights in development, lineage relationships, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

A T-bet gradient controls the fate and function of CCR6-RORγt+ innate lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Lineage Relationship Analysis of RORγt+Innate Lymphoid Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Regulated expression of nuclear receptor RORγt confers distinct functional fates to NK cell receptor-expressing RORγt(+) innate lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Inducible lymphoid tissues in the adult gut: recapitulation of a fetal developmental pathway?

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Systemically dispersed innate IL-13-expressing cells in type 2 immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Acute gastrointestinal infection induces long-lived microbiota-specific T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Antibodies to interleukin 12 abrogate established experimental colitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Ustekinumab induction and maintenance therapy in refractory Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Anti-interleukin-12 antibody for active Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Fontolizumab in moderate to severe Crohn's disease: a phase 2, randomized, double-blind, placebo-controlled, multiple-dose study

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Interleukin-23 drives intestinal inflammation through direct activity on T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Regulation of inflammatory responses by IL-17F

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

A protective function for interleukin 17A in T cell-mediated intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Contextual regulation of inflammation: a duet by transforming growth factor-beta and interleukin-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Th17 and regulatory T cells in mediating and restraining inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Basiliximab does not increase efficacy of corticosteroids in patients with steroid-refractory ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Daclizumab, a humanised monoclonal antibody to the interleukin 2 receptor (CD25), for the treatment of moderately to severely active ulcerative colitis: a randomised, double blind, placebo controlled, dose ranging trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Natalizumab for the treatment of active Crohn's disease: results of the ENCORE Trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Genes and environment: how will our concepts on the pathophysiology of IBD develop in the future?

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Inflammatory bowel disease and mutations affecting the interleukin-10 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Tofacitinib, an oral Janus kinase inhibitor, in active ulcerative colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2012-303955

10.1136/GUTJNL-2012-303955

21 January 2018

Identifiers

DOI

1 reference

5 August 2017

1 reference