(Q35012043)

5 August 2017

title

β-escin reverses multidrug resistance through inhibition of the GSK3β/β-catenin pathway in cholangiocarcinoma (English)

1 reference

5 August 2017

0 references

multiple drug resistance

1 reference

Gui-Li Huang

1

1 reference

5 August 2017

Dong-Yan Shen

2

1 reference

5 August 2017

Cheng-Fu Cai

3

1 reference

5 August 2017

Qiu-Yan Zhang

4

1 reference

5 August 2017

Hong-Yue Ren

5

1 reference

5 August 2017

Qing-Xi Chen

6

1 reference

5 August 2017

language of work or name

English

0 references

publication date

1 January 2015

1 reference

World Journal of Gastroenterology

5 August 2017

published in

1 reference

5 August 2017

volume

21

1 reference

5 August 2017

issue

4

1 reference

5 August 2017

page(s)

1148-1157

1 reference

Inhibition of Wnt/β-catenin signaling downregulates P-glycoprotein and reverses multi-drug resistance of cholangiocarcinoma

5 August 2017

cites work

1 reference

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Oncogenic activity of retinoic acid receptor γ is exhibited through activation of the Akt/NF-κB and Wnt/β-catenin pathways in cholangiocarcinoma

8 July 2018

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GSK3β phosphorylation of the KLF6 tumor suppressor promotes its transactivation of p21.

8 July 2018

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Interference of Frizzled 1 (FZD1) reverses multidrug resistance in breast cancer cells through the Wnt/β-catenin pathway

8 July 2018

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Three decades of P-gp inhibitors: skimming through several generations and scaffolds.

8 July 2018

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Small molecule-based disruption of the Axin/β-catenin protein complex regulates mesenchymal stem cell differentiation

8 July 2018

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β-Escin sodium inhibits inducible nitric oxide synthase expression via downregulation of the JAK/STAT pathway in A549 cells

8 July 2018

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Apoptosis of human cholangiocarcinoma cell lines induced by β-escin through mitochondrial caspase-dependent pathway

8 July 2018

1 reference

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Tamoxifen reverses the multi-drug-resistance of an established human cholangiocarcinoma cell line in combined chemotherapeutics

8 July 2018

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Reversal of multidrug resitance by natural substances from plants

8 July 2018

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An updated overview on Wnt signaling pathways: a prelude for more

8 July 2018

1 reference

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Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.

8 July 2018

1 reference

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Establishment and identification of the human multi-drug-resistant cholangiocarcinoma cell line QBC939/ADM.

8 July 2018

1 reference

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Synergistic effects of beta-aescin and 5-fluorouracil in human hepatocellular carcinoma SMMC-7721 cells

8 July 2018

1 reference

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Role of Wnt/β-catenin signaling in liver metabolism and cancer

8 July 2018

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8 July 2018

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Burden of digestive diseases in the United States Part III: Liver, biliary tract, and pancreas

8 July 2018

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Recent advances in P-glycoprotein-mediated multidrug resistance reversal mechanisms

8 July 2018

1 reference

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Wnt/beta-catenin signaling in development and disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306158

Diseases of Wnt signaling

8 July 2018

1 reference

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CEACAM6 gene expression in intrahepatic cholangiocarcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306158

Beta-escin inhibits colonic aberrant crypt foci formation in rats and regulates the cell cycle growth by inducing p21(waf1/cip1) in colon cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306158

An update on overcoming MDR1-mediated multidrug resistance in cancer chemotherapy

8 July 2018

1 reference

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Wnt signalling in stem cells and cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306158

The epidemiology of cholangiocarcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306158

Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306158

Staging laparoscopy in patients with extrahepatic biliary carcinoma. Analysis of 100 patients

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306158

Aescin: pharmacology, pharmacokinetics and therapeutic profile

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306158

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

8 July 2018

1 reference

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Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation

8 July 2018

1 reference

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Beta-escin, a natural triterpenoid saponin from Chinese horse chestnut seeds, depresses HL-60 human leukaemia cell proliferation and induces apoptosis

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.3748%2FWJG.V21.I4.1148

Wnt3a/β-catenin increases proliferation in heart valve interstitial cells

21 January 2018

1 reference

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Synergistic interactions of saponins and monoterpenes in HeLa cells, Cos7 cells and in erythrocytes.

25 October 2018

1 reference

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Escin attenuates acute lung injury induced by endotoxin in mice.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306158

Tamoxifen (TMX)/Fas induced growth inhibition of human cholangiocarcinoma (HCC) by gamma interferon (IFN-gamma).

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306158

Escin augments the efficacy of gemcitabine through down-regulation of nuclear factor-κB and nuclear factor-κB-regulated gene products in pancreatic cancer both in vitro and in vivo

25 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25632187

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/25632187

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3748/WJG.V21.I4.1148

1 reference

5 August 2017

1 reference

5 August 2017

1 reference