(Q35015343)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

Araguspongine C induces autophagic death in breast cancer cells through suppression of c-Met and HER2 receptor tyrosine kinase signaling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Hassan Y Ebrahim

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Mohamed M Mohyeldin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

author name string

Mohamed R Akl

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Khaled Y Orabi

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Ahmed I Foudah

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Khalid A El Sayed

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

publication date

8 January 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

page(s)

288-311

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

27 February 2020

copyright license

start time

8 January 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Olive phenolics as c-Met inhibitors: (-)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer models

8 July 2018

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The marine-derived sipholenol A-4-O-3',4'-dichlorobenzoate inhibits breast cancer growth and motility in vitro and in vivo through the suppression of Brk and FAK signaling

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Autophagy in breast cancer and its implications for therapy

8 July 2018

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Interaction between Her2 and Beclin-1 proteins underlies a new mechanism of reciprocal regulation

8 July 2018

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Autophagy as a target for cancer therapy: new developments

8 July 2018

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Role of the inositol 1,4,5-trisphosphate receptor/Ca2+-release channel in autophagy

8 July 2018

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8 July 2018

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Design and synthesis of novel human epidermal growth factor receptor 2 (HER2)/epidermal growth factor receptor (EGFR) dual inhibitors bearing a pyrrolo[3,2-d]pyrimidine scaffold

8 July 2018

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Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival

8 July 2018

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(-)-Oleocanthal as a c-Met inhibitor for the control of metastatic breast and prostate cancers

8 July 2018

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Chemical modulators of autophagy as biological probes and potential therapeutics

8 July 2018

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Growth factor signaling pathways as targets for prevention of epithelial carcinogenesis.

8 July 2018

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Inositol 1,4,5-trisphosphate-induced Ca2+ signalling is involved in estradiol-induced breast cancer epithelial cell growth

8 July 2018

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Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors

8 July 2018

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Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer

8 July 2018

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Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab

8 July 2018

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Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer.

8 July 2018

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MET pathway as a therapeutic target

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306938

The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1.

8 July 2018

1 reference

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8 July 2018

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8 July 2018

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Lithium induces autophagy by inhibiting inositol monophosphatase

8 July 2018

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Xestospongin B, a competitive inhibitor of IP3-mediated Ca2+ signalling in cultured rat myotubes, isolated myonuclei, and neuroblastoma (NG108-15) cells.

8 July 2018

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Platelet aggregation inhibitors from Philippine marine invertebrate samples screened in a new microplate assay

8 July 2018

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Araguspongines K and L, new bioactive bis-1-oxaquinolizidine N-oxide alkaloids from Red Sea specimens of Xestospongia exigua

8 July 2018

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8 July 2018

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Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

8 July 2018

1 reference

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Crystal structure of the tyrosine kinase domain of the human insulin receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306938

Hydroxylated xestospongins block inositol-1,4,5-trisphosphate-induced Ca2+ release and sensitize Ca2+-induced Ca2+ release mediated by ryanodine receptors

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FMD13010288

Met acts on Mdm2 via mTOR to signal cell survival during development.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FMD13010288

PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKa Predictions

21 January 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306938

25 October 2018

https://api.crossref.org/works/10.3390%2FMD13010288

Inhibition of c-Met promoted apoptosis, autophagy and loss of the mitochondrial transmembrane potential in oridonin-induced A549 lung cancer cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25580621

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Xestospongin C is an equally potent inhibitor of the inositol 1,4,5-trisphosphate receptor and the endoplasmic-reticulum Ca(2+) pumps

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25580621

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3390/MD13010288

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

PubMed publication ID

25580621

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25580621%20AND%20SRC:MED&resulttype=core&format=json