(Q35015668)

5 August 2017

title

Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice (English)

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5 August 2017

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1 reference

4

Ninotchka L Sigua

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5 August 2017

Heinz Fehrenbach

5

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ORCID Public Data File 2021

author name string

Matthias Clauss

1

1 reference

5 August 2017

Robert Voswinckel

2

1 reference

5 August 2017

Gangaraju Rajashekhar

3

1 reference

5 August 2017

Natalia I Rush

6

1 reference

5 August 2017

Kelly S Schweitzer

7

1 reference

5 August 2017

Ali Ö Yildirim

8

1 reference

5 August 2017

Krzysztof Kamocki

9

1 reference

5 August 2017

Amanda J Fisher

10

1 reference

5 August 2017

Yuan Gu

11

1 reference

5 August 2017

Bilal Safadi

12

1 reference

5 August 2017

Sandeep Nikam

13

1 reference

5 August 2017

Walter C Hubbard

14

1 reference

5 August 2017

Rubin M Tuder

15

1 reference

5 August 2017

Homer L Twigg

16

1 reference

5 August 2017

Robert G Presson

17

1 reference

5 August 2017

Sanjay Sethi

18

1 reference

5 August 2017

Irina Petrache

19

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5 August 2017

language of work or name

English

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publication date

16 May 2011

1 reference

Journal of Clinical Investigation

5 August 2017

published in

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5 August 2017

volume

121

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5 August 2017

issue

6

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5 August 2017

page(s)

2470-2479

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describes a project that uses

5 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3104742/fullTextXML

inferred from PubMed Central ID database lookup

cites work

A monoclonal rat anti-mouse EMAP II antibody that functionally neutralizes pro- and mature-EMAP II in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Targeted induction of lung endothelial cell apoptosis causes emphysema-like changes in the mouse

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Stat3 downstream genes serve as biomarkers in human lung carcinomas and chronic obstructive pulmonary disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Distal airways in mice exposed to cigarette smoke: Nrf2-regulated genes are increased in Clara cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Functional significance of apoptosis in chronic obstructive pulmonary disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

alpha-1 antitrypsin inhibits caspase-3 activity, preventing lung endothelial cell apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Identification of protease-sensitive sites in Human Endothelial-Monocyte Activating Polypeptide II protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Expression of the reverse tetracycline-transactivator gene causes emphysema-like changes in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Alveolar wall apoptosis causes lung destruction and emphysematous changes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Regulation of EMAP II by hypoxia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Proteinases in chronic obstructive pulmonary disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Attenuation of pulmonary neuroendocrine differentiation in mice lacking Clara cell secretory protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Endothelial monocyte activating polypeptide II induces endothelial cell apoptosis and may inhibit tumor angiogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

The molecular basis of lung morphogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

The endothelial monocyte-activating polypeptide II (EMAP II) is a substrate for caspase-7.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Highly differentiated motifs responsible for two cytokine activities of a split human tRNA synthetase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Endothelial-monocyte activating polypeptide II, a novel antitumor cytokine that suppresses primary and metastatic tumor growth and induces apoptosis in growing endothelial cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Two distinct cytokines released from a human aminoacyl-tRNA synthetase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Regulation of endothelial monocyte-activating polypeptide II release by apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

The p43 component of the mammalian multi-synthetase complex is likely to be the precursor of the endothelial monocyte-activating polypeptide II cytokine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Characterization of a novel tumor-derived cytokine. Endothelial-monocyte activating polypeptide II

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

A peptide derived from the amino terminus of endothelial-monocyte-activating polypeptide II modulates mononuclear and polymorphonuclear leukocyte functions, defines an apparently novel cellular interaction site, and induces an acute inflammatory res

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Endothelial monocyte-activating polypeptide II. A novel tumor-derived polypeptide that activates host-response mechanisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Assessment of air space size characteristics by intercept (chord) measurement: an accurate and efficient stereological approach

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Doxycycline treatment prevents alveolar destruction in VEGF-deficient mouse lung.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Potential role for antiangiogenic proteins in the evolution of bronchopulmonary dysplasia.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Apoptosis and emphysema: the missing link.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Increased expression of the chemokine receptor CXCR3 and its ligand CXCL10 in peripheral airways of smokers with chronic obstructive pulmonary disease.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Pro-EMAP II is not primarily cleaved by caspase-3 and -7.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

FGF-10 disrupts lung morphogenesis and causes pulmonary adenomas in vivo.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Expression of EMAP II in the developing and adult mouse.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Endothelial monocyte activating polypeptide II inhibits lung neovascularization and airway epithelial morphogenesis.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Stereological estimation of the volume weighted mean volumes of alveoli and acinar pathways in the rat lung to characterise alterations after ischaemia/reperfusion.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104742

Prostate adenocarcinoma cells release the novel proinflammatory polypeptide EMAP-II in response to stress

25 October 2018

1 reference

12 December 2020

Effects of cigarette smoke in mice with different levels of alpha(1)-proteinase inhibitor and sensitivity to oxidants

1 reference

12 December 2020

A novel tumor-derived mediator that sensitizes cytokine-resistant tumors to tumor necrosis factor

1 reference

12 December 2020

Endothelial-monocyte-activating polypeptide II induces migration of endothelial progenitor cells via the chemokine receptor CXCR3

1 reference

12 December 2020

CCR3 monoclonal antibody inhibits airway eosinophilic inflammation and mucus overproduction in a mouse model of asthma

1 reference

12 December 2020

Expression and function of endothelial monocyte-activating polypeptide-II in acute lung inflammation

1 reference

12 December 2020

CXCR3 and CCR5 Chemokines in Induced Sputum From Patients With COPD

1 reference

12 December 2020

Endothelial monocyte activating polypeptide II interferes with VEGF-induced proangiogenic signaling

1 reference

12 December 2020

Different lung responses to cigarette smoke in two strains of mice sensitive to oxidants

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI43881

1 reference

5 August 2017

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5 August 2017

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