(Q35016431)

5 August 2017

title

USP22 promotes NSCLC tumorigenesis via MDMX up-regulation and subsequent p53 inhibition (English)

1 reference

non-small-cell lung carcinoma

5 August 2017

main subject

1 reference

Fangbao Ding

1

1 reference

5 August 2017

Chunrong Bao

2

1 reference

5 August 2017

Yue Tian

3

1 reference

5 August 2017

Haibo Xiao

4

1 reference

5 August 2017

Mingsong Wang

5

1 reference

5 August 2017

Xiao Xie

6

1 reference

5 August 2017

Fengqing Hu

7

1 reference

5 August 2017

Ju Mei

8

1 reference

5 August 2017

language of work or name

English

0 references

publication date

25 December 2014

1 reference

International Journal of Molecular Sciences

5 August 2017

published in

1 reference

5 August 2017

volume

16

1 reference

5 August 2017

issue

1

1 reference

5 August 2017

page(s)

307-320

1 reference

Creative Commons Attribution 4.0 International

5 August 2017

copyright license

start time

25 December 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Overexpression of ubiquitin-specific protease 22 predicts poor survival in patients with early-stage non-small cell lung cancer

8 July 2018

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8 July 2018

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A synthetic form of frizzled 8-associated antiproliferative factor enhances p53 stability through USP2a and MDM2

8 July 2018

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Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2-amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

1 reference

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USP22 acts as an oncogene by the activation of BMI-1-mediated INK4a/ARF pathway and Akt pathway

8 July 2018

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Blockade of Hsp90 by 17AAG antagonizes MDMX and synergizes with Nutlin to induce p53-mediated apoptosis in solid tumors

8 July 2018

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8 July 2018

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A small-molecule inhibitor of MDMX activates p53 and induces apoptosis

8 July 2018

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Silencing USP22 by asymmetric structure of interfering RNA inhibits proliferation and induces cell cycle arrest in bladder cancer cells

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

1 reference

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8 July 2018

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8 July 2018

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USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A

8 July 2018

1 reference

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The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4307248

Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4307248

Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer

8 July 2018

1 reference

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A dynamic role of HAUSP in the p53-Mdm2 pathway

8 July 2018

1 reference

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8 July 2018

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Zinc-finger UBPs: regulators of deubiquitylation

8 July 2018

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USP22 antagonizes p53 transcriptional activation by deubiquitinating Sirt1 to suppress cell apoptosis and is required for mouse embryonic development.

21 January 2018

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Increased expression of ubiquitin-specific protease 22 can promote cancer progression and predict therapy failure in human colorectal cancer.

21 January 2018

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Expression patterns of USP22 and potential targets BMI-1, PTEN, p-AKT in non-small-cell lung cancer.

21 January 2018

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Prognostic significance of USP22 as an oncogene in papillary thyroid carcinoma

21 January 2018

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Ubiquitin-specific protease 22: a novel molecular biomarker in cervical cancer prognosis and therapeutics

21 January 2018

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Small molecules that bind the Mdm2 RING stabilize and activate p53.

21 January 2018

1 reference

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The co-expression of USP22 and BMI-1 may promote cancer progression and predict therapy failure in gastric carcinoma

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25547493

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3390/IJMS16010307

1 reference

5 August 2017

1 reference

5 August 2017

1 reference