(Q35016805)

5 August 2017

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title

Unleashing formins to remodel the actin and microtubule cytoskeletons (English)

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5 August 2017

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Melissa A Chesarone

1

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PubMed ID

19997130

5 August 2017

Amy Grace DuPage

series ordinal

2

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PubMed ID

19997130

5 August 2017

Bruce L Goode

series ordinal

3

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5 August 2017

9 December 2009

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Nature Reviews Molecular Cell Biology

5 August 2017

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5 August 2017

11

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5 August 2017

62-74

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5 August 2017

1

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https://scigraph.springernature.com/pub.10.1038/nrm2816

5 August 2017

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cites work

Mechanism and function of formins in the control of actin assembly

1 reference

Microtubule stabilization: formins assert their independence

31 March 2020

1 reference

Actin nucleation and elongation factors: mechanisms and interplay

31 March 2020

1 reference

p53-cofactor JMY is a multifunctional actin nucleation factor

31 March 2020

1 reference

Formin proteins: a domain-based approach.

31 March 2020

1 reference

Roots of angiosperm formins: the evolutionary history of plant FH2 domain-containing proteins

31 March 2020

1 reference

Origins and evolution of the formin multigene family that is involved in the formation of actin filaments

31 March 2020

1 reference

Interaction of profilin with G-actin and poly(L-proline)

31 March 2020

1 reference

The structure of crystalline profilin-beta-actin

31 March 2020

1 reference

High-resolution structural analysis of mammalian profilin 2a complex formation with two physiological ligands: the formin homology 1 domain of mDia1 and the proline-rich domain of VASP

31 March 2020

1 reference

The fission yeast cytokinesis formin Cdc12p is a barbed end actin filament capping protein gated by profilin

31 March 2020

1 reference

Regulation and targeting of the fission yeast formin cdc12p in cytokinesis

31 March 2020

1 reference

An actin nucleation mechanism mediated by Bni1 and profilin

31 March 2020

1 reference

Energetic requirements for processive elongation of actin filaments by FH1FH2-formins

31 March 2020

1 reference

EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration

31 March 2020

1 reference

The microtubule-binding protein CLIP-170 coordinates mDia1 and actin reorganization during CR3-mediated phagocytosis

31 March 2020

1 reference

The formin mDia2 stabilizes microtubules independently of its actin nucleation activity

31 March 2020

1 reference

Phylogenetic analysis of the formin homology 2 domain

31 March 2020

1 reference

Structural and mechanistic insights into the interaction between Rho and mammalian Dia.

31 March 2020

1 reference

Structural basis of Rho GTPase-mediated activation of the formin mDia1.

31 March 2020

1 reference

Structure of the autoinhibitory switch in formin mDia1.

31 March 2020

1 reference

Specificity of Interactions between mDia Isoforms and Rho Proteins

31 March 2020

1 reference

Biochemical characterization of the diaphanous autoregulatory interaction in the formin homology protein FHOD1

31 March 2020

1 reference

The basic region of the diaphanous-autoregulatory domain (DAD) is required for autoregulatory interactions with the diaphanous-related formin inhibitory domain

31 March 2020

1 reference

The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition

31 March 2020

1 reference

Mechanism of activation of the Formin protein Daam1

31 March 2020

1 reference

Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1

31 March 2020

1 reference

Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion

31 March 2020

1 reference

Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor delta 2 subunit

31 March 2020

1 reference

Characterization of the delta2 glutamate receptor-binding protein delphilin: Splicing variants with differential palmitoylation and an additional PDZ domain.

31 March 2020

1 reference

Arabidopsis group Ie formins localize to specific cell membrane domains, interact with actin-binding proteins and cause defects in cell expansion upon aberrant expression.

31 March 2020

1 reference

Mechanism of formin-induced nucleation of actin filaments

31 March 2020

1 reference

A conserved mechanism for Bni1- and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin

31 March 2020

1 reference

Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture

31 March 2020

1 reference

Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain

31 March 2020

1 reference

Thermodynamics and kinetics of actin filament nucleation.

31 March 2020

1 reference

G-actin regulates rapid induction of actin nucleation by mDia1 to restore cellular actin polymers

31 March 2020

1 reference

The mammalian formin FHOD1 is activated through phosphorylation by ROCK and mediates thrombin-induced stress fibre formation in endothelial cells

31 March 2020

1 reference

The Diaphanous-related Formin FHOD1 associates with ROCK1 and promotes Src-dependent plasma membrane blebbing

31 March 2020

1 reference

Differential activities and regulation of Saccharomyces cerevisiae formin proteins Bni1 and Bnr1 by Bud6.

31 March 2020

1 reference

Regulation of the formin for3p by cdc42p and bud6p

31 March 2020

1 reference

Identification of a short Spir interaction sequence at the C-terminal end of formin subgroup proteins

31 March 2020

1 reference

Capu and Spire assemble a cytoplasmic actin mesh that maintains microtubule organization in the Drosophila oocyte

31 March 2020

1 reference

Regulatory interactions between two actin nucleators, Spire and Cappuccino

31 March 2020

1 reference

Role of formins in actin assembly: nucleation and barbed-end association

31 March 2020

1 reference

Formin Leaky Cap Allows Elongation in the Presence of Tight Capping Proteins

31 March 2020

1 reference

Insertional assembly of actin filament barbed ends in association with formins produces piconewton forces

31 March 2020

1 reference

Actin polymerization-driven molecular movement of mDia1 in living cells

31 March 2020

1 reference

Rapid formin-mediated actin-filament elongation is essential for polarized plant cell growth

31 March 2020

1 reference

Clustering of VASP actively drives processive, WH2 domain-mediated actin filament elongation

31 March 2020

1 reference

Formin is a processive motor that requires profilin to accelerate actin assembly and associated ATP hydrolysis

31 March 2020

1 reference

Control of the assembly of ATP- and ADP-actin by formins and profilin.

31 March 2020

1 reference

Model of formin-associated actin filament elongation

31 March 2020

1 reference

Formin differentially utilizes profilin isoforms to rapidly assemble actin filaments

31 March 2020

1 reference

Mechanistic Differences in Actin Bundling Activity of Two Mammalian Formins, FRL1 and mDia2

31 March 2020

1 reference

The formin homology 1 domain modulates the actin nucleation and bundling activity of Arabidopsis FORMIN1.

31 March 2020

1 reference

Interaction of the N- and C-terminal autoregulatory domains of FRL2 does not inhibit FRL2 activity.

31 March 2020

1 reference

The mouse formin, FRLalpha, slows actin filament barbed end elongation, competes with capping protein, accelerates polymerization from monomers, and severs filaments

31 March 2020

1 reference

INF2 Is a WASP homology 2 motif-containing formin that severs actin filaments and accelerates both polymerization and depolymerization.

31 March 2020

1 reference

Cloning and functional characterization of a formin-like protein (AtFH8) from Arabidopsis

31 March 2020

1 reference

Positive feedback interactions between microtubule and actin dynamics during cell motility

31 March 2020

1 reference

Functional cooperation between the microtubule and actin cytoskeletons

31 March 2020

1 reference

Export from pericentriolar endocytic recycling compartment to cell surface depends on stable, detyrosinated (glu) microtubules and kinesin.

31 March 2020

1 reference

mDia mediates Rho-regulated formation and orientation of stable microtubules

31 March 2020

1 reference

Formin-dependent synaptic growth: evidence that Dlar signals via Diaphanous to modulate synaptic actin and dynamic pioneer microtubules

31 March 2020

1 reference

Control of mitotic spindle position by the Saccharomyces cerevisiae formin Bni1p

31 March 2020

1 reference

Dissecting the involvement of formins in Bud6p-mediated cortical capture of microtubules in S. cerevisiae.

31 March 2020

1 reference

Cdc42 and mDia3 regulate microtubule attachment to kinetochores

31 March 2020

1 reference

Targeting, capture, and stabilization of microtubules at early focal adhesions

31 March 2020

1 reference

Myosin V orientates the mitotic spindle in yeast

31 March 2020

1 reference

The role of the proteins Kar9 and Myo2 in orienting the mitotic spindle of budding yeast

31 March 2020

1 reference

INF1 is a novel microtubule-associated formin

31 March 2020

1 reference

Coordination of microtubule and microfilament dynamics by Drosophila Rho1, Spire and Cappuccino

31 March 2020

1 reference

Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2

31 March 2020

1 reference

Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast

31 March 2020

1 reference

Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

31 March 2020

1 reference

Yeast formins regulate cell polarity by controlling the assembly of actin cables.

31 March 2020

1 reference

WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells

31 March 2020

1 reference

31 March 2020

1 reference

Identification of a carboxyl-terminal diaphanous-related formin homology protein autoregulatory domain

31 March 2020

1 reference

Dissecting requirements for auto-inhibition of actin nucleation by the formin, mDia1.

31 March 2020

1 reference

Autoinhibition regulates cellular localization and actin assembly activity of the diaphanous-related formins FRLalpha and mDia1.

31 March 2020

1 reference

Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly

31 March 2020

1 reference

Crystal structure of human DAAM1 formin homology 2 domain

31 March 2020

1 reference

INF2 is an endoplasmic reticulum-associated formin protein.

31 March 2020

1 reference

Dia-interacting protein modulates formin-mediated actin assembly at the cell cortex.

31 March 2020

1 reference

Displacement of formins from growing barbed ends by bud14 is critical for actin cable architecture and function

31 March 2020

1 reference

Mammalian Rho GTPases: new insights into their functions from in vivo studies

31 March 2020

1 reference

Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae

31 March 2020

1 reference

Formin-dependent actin assembly is regulated by distinct modes of Rho signaling in yeast

31 March 2020

1 reference

Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation

31 March 2020

1 reference

Regulation of the yeast formin Bni1p by the actin-regulating kinase Prk1p

31 March 2020

1 reference

Pheromone-induced polarization is dependent on the Fus3p MAPK acting through the formin Bni1p.

31 March 2020

1 reference

Rho1 directs formin-mediated actin ring assembly during budding yeast cytokinesis

31 March 2020

1 reference

Polo-like kinase Cdc5 controls the local activation of Rho1 to promote cytokinesis.

31 March 2020

1 reference

Regulation of cell diameter, For3p localization, and cell symmetry by fission yeast Rho-GAP Rga4p

31 March 2020

1 reference

The diaphanous inhibitory domain/diaphanous autoregulatory domain interaction is able to mediate heterodimerization between mDia1 and mDia2.

31 March 2020

1 reference

Mammalian diaphanous-related formin Dia1 controls the organization of E-cadherin-mediated cell-cell junctions.

31 March 2020

1 reference

FH3, a domain found in formins, targets the fission yeast formin Fus1 to the projection tip during conjugation

31 March 2020

1 reference

An FH domain-containing Bnr1p is a multifunctional protein interacting with a variety of cytoskeletal proteins in Saccharomyces cerevisiae

31 March 2020

1 reference

Rho1p-Bni1p-Spa2p interactions: implication in localization of Bni1p at the bud site and regulation of the actin cytoskeleton in Saccharomyces cerevisiae

31 March 2020

1 reference

Tea4p links microtubule plus ends with the formin for3p in the establishment of cell polarity.

31 March 2020

1 reference

Regulation of cell-cell adhesion by Abi/Diaphanous complexes.

31 March 2020

1 reference

Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables

31 March 2020

1 reference

The ARP2/3 complex: an actin nucleator comes of age

31 March 2020

1 reference

Formin proteins: purification and measurement of effects on actin assembly.

31 March 2020

1 reference

Yeast formins Bni1 and Bnr1 utilize different modes of cortical interaction during the assembly of actin cables

31 March 2020

1 reference

Dynamics of the formin for3p in actin cable assembly.

31 March 2020

1 reference

Protein complexes regulating Arp2/3-mediated actin assembly.

31 March 2020

1 reference

Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains

31 March 2020

2 references

31 March 2020

12 December 2020

The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics

1 reference

Molecular interaction between limb deformity proteins (formins) and Src family kinases

31 March 2020

1 reference

RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase

31 March 2020

1 reference

Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2

31 March 2020

1 reference

IRSp53: crossing the road of membrane and actin dynamics in the formation of membrane protrusions

31 March 2020

1 reference

Identification of Novel Graded Polarity Actin Filament Bundles in Locomoting Heart Fibroblasts: Implications for the Generation of Motile Force

31 March 2020

1 reference

Directionality of F-actin cables changes during the fission yeast cell cycle.

31 March 2020

1 reference

Three-dimensional arrangement of F-actin in the contractile ring of fission yeast

31 March 2020

1 reference

Visualization of mitochondrial movement in yeast

31 March 2020

1 reference

Role of tropomyosin in formin-mediated contractile ring assembly in fission yeast

31 March 2020

1 reference

Ubiquitin-mediated degradation of the formin mDia2 upon completion of cell division

31 March 2020

1 reference

Human leukocyte formin: a novel protein expressed in lymphoid malignancies and associated with Akt.

31 March 2020

1 reference

High expression of FMNL1 protein in T non-Hodgkin's lymphomas.

31 March 2020

1 reference

Overexpression of FMNL2 is closely related to metastasis of colorectal cancer

31 March 2020

1 reference

31 March 2020

1 reference

31 March 2020

RHO-GTPases and cancer

1 reference

Mitf regulation of Dia1 controls melanoma proliferation and invasiveness

31 March 2020

1 reference

T cell responses in mammalian diaphanous-related formin mDia1 knock-out mice.

31 March 2020

1 reference

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

31 March 2020

1 reference

An integrated genomic analysis of human glioblastoma multiforme

31 March 2020

1 reference

Allorestricted T cells with specificity for the FMNL1-derived peptide PP2 have potent antitumor activity against hematologic and other malignancies

31 March 2020

1 reference

Myeloproliferative defects following targeting of the Drf1 gene encoding the mammalian diaphanous related formin mDia1.

31 March 2020

1 reference

Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse

31 March 2020

1 reference

A role for mammalian diaphanous-related formins in complement receptor (CR3)-mediated phagocytosis in macrophages

31 March 2020

1 reference

Formin-2, polyploidy, hypofertility and positioning of the meiotic spindle in mouse oocytes

31 March 2020

1 reference

Formin-2 is required for spindle migration and for the late steps of cytokinesis in mouse oocytes.

31 March 2020

1 reference

RhoGEF2 and the formin Dia control the formation of the furrow canal by directed actin assembly during Drosophila cellularisation.

31 March 2020

1 reference

Formin1 disruption confers oligodactylism and alters Bmp signaling

31 March 2020

1 reference

A human homologue of the Drosophila melanogaster diaphanous gene is disrupted in a patient with premature ovarian failure: evidence for conserved function in oogenesis and implications for human sterility

31 March 2020

1 reference

Nonsyndromic deafness DFNA1 associated with mutation of a human homolog of the Drosophila gene diaphanous

31 March 2020

1 reference

The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia.

31 March 2020

1 reference

Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells

31 March 2020

1 reference

Aip3p/Bud6p, a yeast actin-interacting protein that is involved in morphogenesis and the selection of bipolar budding sites

31 March 2020

1 reference

Formin-induced actin cables are required for polarized recruitment of the Ste5 scaffold and high level activation of MAPK Fus3.

31 March 2020

1 reference

Dynamic localization and function of Bni1p at the sites of directed growth in Saccharomyces cerevisiae

31 March 2020

1 reference

The PCH family protein, Cdc15p, recruits two F-actin nucleation pathways to coordinate cytokinetic actin ring formation in Schizosaccharomyces pombe

31 March 2020

1 reference

Regulation of a formin complex by the microtubule plus end protein tea1p

31 March 2020

1 reference

Galpha12/13 is essential for directed cell migration and localized Rho-Dia1 function

31 March 2020

1 reference

RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1.

31 March 2020

1 reference

The Rho family GTPase Rif induces filopodia through mDia2.

31 March 2020

1 reference

Identification and comparative expression analyses of Daam genes in mouse and Xenopus

31 March 2020

1 reference

The Drosophila formin DAAM regulates the tracheal cuticle pattern through organizing the actin cytoskeleton.

31 March 2020

1 reference

Formin proteins of the DAAM subfamily play a role during axon growth.

31 March 2020

1 reference

Identification and characterization of a novel Delphilin variant with an alternative N-terminus

31 March 2020

1 reference

Stress fibers are generated by two distinct actin assembly mechanisms in motile cells

31 March 2020

1 reference

Src regulates the activity of the mammalian formin protein FHOD1.

31 March 2020

1 reference

FHOD1 coordinates actin filament and microtubule alignment to mediate cell elongation

31 March 2020

1 reference

The human formin FHOD1 contains a bipartite structure of FH3 and GTPase-binding domains required for activation

31 March 2020

1 reference

Analysis of the function of Spire in actin assembly and its synergy with formin and profilin

31 March 2020

1 reference

Formin 1-isoform IV deficient cells exhibit defects in cell spreading and focal adhesion formation

31 March 2020

1 reference

A new model for asymmetric spindle positioning in mouse oocytes.

31 March 2020

1 reference

Actin-driven chromosomal motility leads to symmetry breaking in mammalian meiotic oocytes

31 March 2020

1 reference

FRL, a novel formin-related protein, binds to Rac and regulates cell motility and survival of macrophages

31 March 2020

1 reference

Structure and function of Formin homology 2 domain

31 March 2020

1 reference

12 December 2020

Profilin is predominantly associated with monomeric actin in Acanthamoeba

1 reference

12 December 2020

Diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene.

1 reference

12 December 2020

Mutations in the Rho1 small GTPase disrupt morphogenesis and segmentation during early Drosophila development.

1 reference

12 December 2020

Direct observation of microtubule-f-actin interaction in cell free lysates

1 reference

12 December 2020

Functional analysis of the Drosophila diaphanous FH protein in early embryonic development

1 reference

12 December 2020

Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRM2816

1 reference

5 August 2017

1 reference

PubMed ID

19997130