(Q35016969)

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Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat).

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scholarly article

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Europe PubMed Central

5 August 2017

Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat). (English)

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Europe PubMed Central

5 August 2017

phase I clinical trial

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pharmacokinetics

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based on heuristic

inferred from title

Charles A. Dinarello

8

object named as

Charles A Dinarello

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Europe PubMed Central

5 August 2017

author name string

Antonio Furlan

1

1 reference

Europe PubMed Central

5 August 2017

Valmen Monzani

2

1 reference

Europe PubMed Central

5 August 2017

Leonid L Reznikov

3

1 reference

Europe PubMed Central

5 August 2017

Flavio Leoni

4

1 reference

Europe PubMed Central

5 August 2017

Gianluca Fossati

5

1 reference

Europe PubMed Central

5 August 2017

Daniela Modena

6

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Europe PubMed Central

5 August 2017

Paolo Mascagni

7

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Europe PubMed Central

5 August 2017

language of work or name

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publication date

22 February 2011

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Europe PubMed Central

5 August 2017

Molecular Medicine

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Europe PubMed Central

5 August 2017

17

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Europe PubMed Central

5 August 2017

5-6

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Europe PubMed Central

5 August 2017

353-362

1 reference

Europe PubMed Central

5 August 2017

https://scigraph.springernature.com/pub.10.2119/molmed.2011.00020

0 references

HDAC inhibition in rheumatoid arthritis and juvenile idiopathic arthritis

1 reference

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Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules

1 reference

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The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivo

1 reference

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Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer

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1 reference

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Phase I clinical trial of histone deacetylase inhibitor: suberoylanilide hydroxamic acid administered intravenously.

1 reference

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Histone deacetylases

1 reference

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Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.

1 reference

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The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin.

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Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

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A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

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The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines

1 reference

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Duration of nuclear NF-kappaB action regulated by reversible acetylation

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1 reference

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31 March 2020

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10.2119/MOLMED.2011.00020

1 reference

Europe PubMed Central

5 August 2017

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1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

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