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A safer vaccine for Alzheimer's disease?
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12470795
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12470795%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
A safer vaccine for Alzheimer's disease?
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12470795
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12470795%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
main subject
Alzheimer's disease
0 references
author
Einar M Sigurdsson
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12470795
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12470795%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
Thomas Wisniewski
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12470795
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12470795%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
author name string
Blas Frangione
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
12470795
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12470795%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
publication date
1 November 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
12470795
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12470795%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
published in
Neurobiology of Aging
1 reference
stated in
Europe PubMed Central
PubMed ID
12470795
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12470795%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
volume
23
1 reference
stated in
Europe PubMed Central
PubMed ID
12470795
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12470795%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
issue
6
1 reference
stated in
Europe PubMed Central
PubMed ID
12470795
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12470795%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
page(s)
1001-1008
1 reference
stated in
Europe PubMed Central
PubMed ID
12470795
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12470795%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
cites work
Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer's Disease from the Perspective of the Systemic and Localized Forms of Amyloidosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced levels of amyloid beta-peptide antibody in Alzheimer disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Approaches to discovery and characterization of inhibitors of amyloid beta-peptide polymerization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High affinity binding of monoclonal antibodies to the sequential epitope EFRH of beta-amyloid peptide is essential for modulation of fibrillar aggregation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
N-terminal EFRH sequence of Alzheimer's beta-amyloid peptide represents the epitope of its anti-aggregating antibodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human antibodies reactive with beta-amyloid protein in Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Piecing together Alzheimer's.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antibody-mediated resolution of light chain-associated amyloid deposits.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoantibodies to amyloid-beta and Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer disease therapeutics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid beta40/42 clearance across the blood-brain barrier following intra-ventricular injections in wild-type, apoE knock-out and human apoE3 or E4 expressing transgenic mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for seeding of beta -amyloid by intracerebral infusion of Alzheimer brain extracts in beta -amyloid precursor protein-transgenic mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prion (PrPSc)-specific epitope defined by a monoclonal antibody
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Passage of human amyloid beta-protein 1-40 across the murine blood-brain barrier.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recognition sequence design for peptidyl modulators of beta-amyloid aggregation and toxicity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid beta peptide as a vaccine for Alzheimer's disease involves receptor-mediated transport at the blood-brain barrier.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Permeability and residual plasma volume of human, Dutch variant, and rat amyloid beta-protein 1-40 at the blood-brain barrier
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor-mediated transport of human amyloid beta-protein 1-40 and 1-42 at the blood-brain barrier.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bilateral injections of amyloid-beta 25-35 into the amygdala of young Fischer rats: behavioral, neurochemical, and time dependent histopathological effects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Local and distant histopathological effects of unilateral amyloid-beta 25-35 injections into the amygdala of young F344 rats.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo reversal of amyloid-beta lesions in rat brain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroautoimmunity: pathogenic implications for Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disaggregation of Alzheimer beta-amyloid by site-directed mAb.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer beta-amyloid peptide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cerebrospinal fluid proteins: III. Normal values of immunoglobulins G, A and M (variations related to race, sex and age)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mouse C1q A-chain sequence alters beta-amyloid-induced complement activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fact and speculation on the function of immune response genes in antigen presentation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biology of A beta amyloid in Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased incidence of anti-beta-amyloid autoantibodies secreted by Epstein-Barr virus transformed B cell lines from patients with Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Can blood-brain barrier play a role in the development of cerebral amyloidosis and Alzheimer's disease pathology.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Blood-brain barrier transport of circulating Alzheimer's amyloid beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900124-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0197-4580(02)00124-0
1 reference
stated in
Europe PubMed Central
PubMed ID
12470795
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12470795%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
PubMed ID
12470795
1 reference
stated in
Europe PubMed Central
PubMed ID
12470795
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12470795%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
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