(Q35021035)

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Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor signaling

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scholarly article

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Europe PubMed Central

5 August 2017

Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor signaling (English)

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Europe PubMed Central

5 August 2017

extracellular matrix

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1 reference

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10

object named as

Dong-Young Noh

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Europe PubMed Central

5 August 2017

author name string

Kyung-min Lee

1

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Europe PubMed Central

5 August 2017

Keesoo Nam

2

1 reference

Europe PubMed Central

5 August 2017

Sunhwa Oh

3

1 reference

Europe PubMed Central

5 August 2017

Juyeon Lim

4

1 reference

Europe PubMed Central

5 August 2017

Young-Pil Kim

5

1 reference

Europe PubMed Central

5 August 2017

Jong Won Lee

6

1 reference

Europe PubMed Central

5 August 2017

Jong-Han Yu

7

1 reference

Europe PubMed Central

5 August 2017

Sei-Hyun Ahn

8

1 reference

Europe PubMed Central

5 August 2017

Sung-Bae Kim

9

1 reference

Europe PubMed Central

5 August 2017

Taehoon Lee

11

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Europe PubMed Central

5 August 2017

Incheol Shin

12

1 reference

Europe PubMed Central

5 August 2017

publication date

11 December 2014

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Europe PubMed Central

5 August 2017

Breast Cancer Research

1 reference

Europe PubMed Central

5 August 2017

16

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Europe PubMed Central

5 August 2017

6

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Europe PubMed Central

5 August 2017

479

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Europe PubMed Central

5 August 2017

https://scigraph.springernature.com/pub.10.1186/s13058-014-0479-6

0 references

Anti-EGFR function of EFEMP1 in glioma cells and patient prognosis

1 reference

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Targeting the MUC1-C oncoprotein downregulates HER2 activation and abrogates trastuzumab resistance in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

8 July 2018

Correlation of ECM1 expression level with the pathogenesis and metastasis of laryngeal carcinoma

1 reference

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8 July 2018

MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial-mesenchymal transition

1 reference

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8 July 2018

Epithelial-to-mesenchymal transition (EMT) confers primary resistance to trastuzumab (Herceptin).

1 reference

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Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration

1 reference

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Expression and clinical significance of extracellular matrix protein 1 and vascular endothelial growth factor-C in lymphatic metastasis of human breast cancer

1 reference

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MUC1 protein expression in tumor cells regulates transcription of proinflammatory cytokines by forming a complex with nuclear factor-κB p65 and binding to cytokine promoters: importance of extracellular domain

1 reference

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Her2/neu extracellular domain shedding in uterine serous carcinoma: implications for immunotherapy with trastuzumab

1 reference

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8 July 2018

Overcoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism.

1 reference

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8 July 2018

Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase

1 reference

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8 July 2018

Galectin-3 regulates MUC1 and EGFR cellular distribution and EGFR downstream pathways in pancreatic cancer cells

1 reference

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8 July 2018

Anti-MUC1 antibody inhibits EGF receptor signaling in cancer cells

1 reference

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8 July 2018

ECM1 controls T(H)2 cell egress from lymph nodes through re-expression of S1P(1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

8 July 2018

Cleavage of galectin-3 by matrix metalloproteases induces angiogenesis in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

8 July 2018

Heterotrimerization of the growth factor receptors erbB2, erbB3, and insulin-like growth factor-i receptor in breast cancer cells resistant to herceptin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

8 July 2018

Protein expression profiling of primary mammary epithelial cells derived from MMTV-neu mice revealed that HER2/NEU-driven changes in protein expression are functionally clustered

1 reference

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8 July 2018

Circulating galectin-3 promotes metastasis by modifying MUC1 localization on cancer cell surface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

8 July 2018

microRNA-205 regulates HER3 in human breast cancer

1 reference

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8 July 2018

MMP-9 controls Schwann cell proliferation and phenotypic remodeling via IGF-1 and ErbB receptor-mediated activation of MEK/ERK pathway

1 reference

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8 July 2018

Galectin-3 cleavage: a novel surrogate marker for matrix metalloproteinase activity in growing breast cancers.

1 reference

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8 July 2018

A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

8 July 2018

Human breast cancer cells selected for resistance to trastuzumab in vivo overexpress epidermal growth factor receptor and ErbB ligands and remain dependent on the ErbB receptor network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

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MMPs-specific PEGylated peptide-DOX conjugate micelles that can contain free doxorubicin

1 reference

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8 July 2018

MUC1 is a novel regulator of ErbB1 receptor trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

8 July 2018

Extracellular matrix protein 1 inhibits the activity of matrix metalloproteinase 9 through high-affinity protein/protein interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

8 July 2018

MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

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Perlecan knockdown in metastatic prostate cancer cells reduces heparin-binding growth factor responses in vitro and tumor growth in vivo

1 reference

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Decreased accessibility and lack of activation of ErbB2 in JIMT-1, a herceptin-resistant, MUC4-expressing breast cancer cell line.

1 reference

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Specific association of annexin 1 with plasma membrane-resident and internalized EGF receptors mediated through the protein core domain

1 reference

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PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

1 reference

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8 July 2018

P27(kip1) down-regulation is associated with trastuzumab resistance in breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

8 July 2018

Extracellular matrix protein 1 (ECM1) is over-expressed in malignant epithelial tumors

1 reference

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8 July 2018

Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis

1 reference

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Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action

1 reference

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Lipoid proteinosis maps to 1q21 and is caused by mutations in the extracellular matrix protein 1 gene (ECM1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

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Proteomics of breast cancer for marker discovery and signal pathway profiling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

8 July 2018

Extracellular matrix protein 1 (ECM1) has angiogenic properties and is expressed by breast tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

8 July 2018

Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

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Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

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Concentrations of galectin-3 in the sera of normal controls and cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

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Differentiation-dependent alternative splicing and expression of the extracellular matrix protein 1 gene in human keratinocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

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Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer

1 reference

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Characterization of the osteogenic stromal cell line MN7: identification of secreted MN7 proteins using two-dimensional polyacrylamide gel electrophoresis, western blotting, and microsequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4308848

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Humanization of an anti-p185HER2 antibody for human cancer therapy

1 reference

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8 July 2018

Extracellular matrix 1 (ECM1) expression is a novel prognostic marker for poor long-term survival in breast cancer: a Hospital-based Cohort Study in Iowa.

1 reference

https://api.crossref.org/works/10.1186%2FS13058-014-0479-6

21 January 2018

Galectin-3 is a novel substrate for human matrix metalloproteinases-2 and -9.

1 reference

https://api.crossref.org/works/10.1186%2FS13058-014-0479-6

21 January 2018

Interaction of extracellular matrix protein 1 with extracellular matrix components: ECM1 is a basement membrane protein of the skin.

1 reference

https://api.crossref.org/works/10.1186%2FS13058-014-0479-6

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Conversion of an MMP-potent scaffold to an MMP-selective HER-2 sheddase inhibitor via scaffold hybridization and subtle P1' permutations

1 reference

https://api.crossref.org/works/10.1186%2FS13058-014-0479-6

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Circulating HER2 extracellular domain and resistance to chemotherapy in advanced breast cancer.

1 reference

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1 reference

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Overexpression of ECM1 contributes to migration and invasion in cholangiocarcinoma cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/25499743

12 December 2020

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10.1186/S13058-014-0479-6

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Europe PubMed Central

5 August 2017

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1 reference

Europe PubMed Central

5 August 2017

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Europe PubMed Central

5 August 2017

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