(Q35025432)

English

Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy

scientific article published on September 2, 2010

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 August 2017

Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

animal disease model

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813770

5 July 2024

9

object named as

Makoto Kuro-o

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PubMed publication ID

5 August 2017

Hiroyuki Kobori

8

object named as

Hiroyuki Kobori

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813770

5 July 2024

author name string

Hye Eun Yoon

1

1 reference

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5 August 2017

Jung Yeon Ghee

2

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5 August 2017

ShangGuo Piao

3

1 reference

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5 August 2017

Ji-Hyun Song

4

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5 August 2017

Dong He Han

5

1 reference

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5 August 2017

Sol Kim

6

1 reference

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5 August 2017

Naro Ohashi

7

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5 August 2017

Chul Woo Yang

10

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5 August 2017

language of work or name

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publication date

2 September 2010

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5 August 2017

full work available at URL

https://academic.oup.com/ndt/article-pdf/26/3/800/5206198/gfq537.pdf

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813770

5 July 2024

http://ndt.oxfordjournals.org/cgi/content/abstract/26/3/800

online access status

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813770

5 July 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20813770/?tool=EBI

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813770

5 July 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20813770/pdf/?tool=EBI

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online access status

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1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813770

5 July 2024

https://europepmc.org/articles/PMC3108350

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813770

5 July 2024

https://europepmc.org/articles/PMC3108350?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813770

5 July 2024

https://doi.org/10.1093/ndt/gfq537

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813770

5 July 2024

http://academic.oup.com/ndt/article-pdf/26/3/800/5206198/gfq537.pdf

Portable Document Format

1 reference

10.1093/NDT/GFQ537

https://api.crossref.org/works/10.1093/NDT/GFQ537

5 July 2024

Nephrology Dialysis Transplantation

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

26

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

800-813

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Established and newly proposed mechanisms of chronic cyclosporine nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Live longer sans the AT1A receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Disruption of the Ang II type 1 receptor promotes longevity in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Renin-angiotensin system inhibitors protect against age-related changes in rat liver mitochondrial DNA content and gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Intrarenal angiotensin II and angiotensinogen augmentation in chronic angiotensin II-infused mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Cyclosporine A induces senescence in renal tubular epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Gene expression profiling identifies FKBP39 as an inhibitor of autophagy in larval Drosophila fat body.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Regulation of oxidative stress by the anti-aging hormone klotho

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Cyclosporine-induced renal injury induces toll-like receptor and maturation of dendritic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Suppression of aging in mice by the hormone Klotho

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Protective effect of the inhibition of the renin-angiotensin system on aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Chronic cyclosporine nephrotoxicity: new insights and preventive strategies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

HMG-CoA reductase inhibitors up-regulate anti-aging klotho mRNA via RhoA inactivation in IMCD3 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Modulation of gene expression by moxonidine in rats with chronic renal failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

AT1 receptor mediated augmentation of intrarenal angiotensinogen in angiotensin II-dependent hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

In vivo klotho gene transfer ameliorates angiotensin II-induced renal damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Interaction of cyclosporine A and the renin-angiotensin system; new perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Comparison of enalapril and valsartan in cyclosporine A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats on high-sodium diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Renoprotective benefits of RAS inhibition: from ACEI to angiotensin II antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Chronic cyclosporine nephropathy: the Achilles' heel of immunosuppressive therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Urinary 8-hydroxy-2'-deoxyguanosine as a biological marker of in vivo oxidative DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

Cyclosporine A induced lipid peroxidation and influence on glucose-6-phosphatase in rat hepatic and renal microsomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

8 July 2018

A combination of Chinese herbs, Astragalus membranaceus var. mongholicus and Angelica sinensis, improved renal microvascular insufficiency in 5/6 nephrectomized rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Expression of protein kinase C isoenzymes alpha, betaI, and delta in subtypes of intercalated cells of mouse kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Klotho reduces apoptosis in experimental ischaemic acute renal failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Oxidative stress decreases klotho expression in a mouse kidney cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Amelioration of cyclosporine nephrotoxicity by irbesartan, A selective AT1 receptor antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Enalapril increases mitochondrial nitric oxide synthase activity in heart and liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Iron chelation and a free radical scavenger suppress angiotensin II-induced downregulation of klotho, an anti-aging gene, in rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Enalapril and losartan attenuate mitochondrial dysfunction in aged rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Synergistic effects of mycophenolate mofetil and losartan in a model of chronic cyclosporine nephropathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Long-term angiotensin II inhibition increases mitochondrial nitric oxide synthase and not antioxidant enzyme activities in rat heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Enalapril prevents fatty liver in nephrotic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Expression of Klotho protein in the inner ear.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Enalapril attenuates oxidative stress in diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Influence of the renin-angiotensin system on epidermal growth factor expression in normal and cyclosporine-treated rat kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Effect of chronic angiotensin II inhibition on the nitric oxide synthase in the normal rat during aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Effects of losartan and amlodipine on intrarenal hemodynamics and TGF-beta(1) plasma levels in a crossover trial in renal transplant recipients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Severely reduced production of klotho in human chronic renal failure kidney.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Long-term inhibition of renin-angiotensin system sustains memory function in aged Dahl rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

The long-term course of cyclosporine-associated chronic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108350

25 October 2018

Adrenochrome reaction implicates oxygen radicals in metabolism of cyclosporine A and FK-506 in rat and human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociation of glomerular filtration rate from tubulointerstitial fibrosis in experimental chronic cyclosporine nephropathy: role of sodium intake

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenesis of cyclosporine nephropathy: roles of angiotensin II and osteopontin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downregulation of the Klotho gene in the kidney under sustained circulatory stress in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of enalapril treatment on the heart of normal rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enalapril prevents tubulointerstitial lesions by hyperoxaluria

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of angiotensin II with losartan attenuates transforming growth factor-beta1 inducible gene-h3 (betaig-h3) expression in a model of chronic cyclosporine nephrotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of senescence-associated cell cycle inhibitor p16INK4a in deteriorating renal transplants and diseased native kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of angiotensin II on expression of toll-like receptor 2 and maturation of dendritic cells in chronic cyclosporine nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nephrotoxicity of immunosuppressive drugs: long-term consequences and challenges for the future

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of chronic angiotensin II inhibition on the cardiovascular system of the normal rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of cyclosporine in osteopontin null mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of apoptosis-related genes in chronic cyclosporine nephrotoxicity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of angiotensin-converting enzyme inhibition on mitochondrial number in the aging mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Journal of Nephrology

20

15

358

author name string

Toblli

publication date

2002

1 reference

10.1093/NDT/GFQ537

https://api.crossref.org/works/10.1093/NDT/GFQ537

5 July 2024

Journal of Pharmacology and Experimental Therapeutics

52

265

1047

author name string

Ahmed

publication date

1993

1 reference

10.1093/NDT/GFQ537

https://api.crossref.org/works/10.1093/NDT/GFQ537

5 July 2024

Research Communications in Chemical Pathology and Pharmacology

53

68

189

author name string

Inselmann

publication date

1990

1 reference

10.1093/NDT/GFQ537

https://api.crossref.org/works/10.1093/NDT/GFQ537

5 July 2024

Identifiers

10.1093/NDT/GFQ537

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

ResearchGate publication ID

0 references

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