(Q35030901)

5 August 2017

title

Amplified interactive toxicity of chemicals at nontoxic levels: mechanistic considerations and implications to public health (English)

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5 August 2017

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Harihara M. Mehendale

series ordinal

1

object named as

Mehendale HM

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5 August 2017

publication date

1 November 1994

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Environmental Health Perspectives

5 August 2017

published in

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5 August 2017

volume

102 Suppl 9

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5 August 2017

page(s)

139-149

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Genetics of carbon tetrachloride-induced liver injury in mice. II. Multigenic regulation

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Strain differences in mice in carbon tetrachloride-induced liver injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Potentiation of halomethane hepatotoxicity: Chlordecone and carbon tetrachloride*1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Potentiation of CCl4 lethality by chlordecone.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Hepatobiliary dysfunction and inhibition of adenosine triphosphatase activity of bile canaliculi-enriched fractions following in vivo mirex, photomirex, and chlordecone exposures*1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Functional and biochemical correlates of chlordecone exposure and its enhancement of CCl4 hepatotoxicity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Effect of pretreatment of rats with carbon tetrachloride on tolerance development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Carbon tetrachloride-induced protection against carbon tetrachloride toxicity. The role of the liver microsomal drug-metabolizing system.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Mechanisms of chloroform and carbon tetrachloride toxicity in primary cultured mouse hepatocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Free radicals and tissue injury: fact and fiction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Cytotoxicity of halogenated alkanes in primary cultures of rat hepatocytes from normal, partial hepatectomized, and preneoplastic/neoplastic liver

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

On radiation, paradigms, and hormesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Protective role of fructose 1,6-bisphosphate during CCl4 hepatotoxicity in rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Selective resistance to cytotoxic agents in hepatocytes isolated from partially hepatectomized and neoplastic mouse liver.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Carbon tetrachloride metabolism in partially hepatectomized and sham-operated rats pre-exposed to chlordecone (Kepone).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Chlordecone (Kepone)-potentiated carbon tetrachloride hepatotoxicity in partially hepatectomized rats--a histomorphometric study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Mechanism of the lethal interaction of chlordecone and CCl4 at non-toxic doses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Protection from chlordecone (Kepone)-potentiated CCl4 hepatotoxicity in rats by fructose 1,6-diphosphate.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Role of hepatocellular regeneration in chlordecone potentiated hepatotoxicity of carbon tetrachloride

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

The time course of liver injury and [3H]thymidine incorporation in chlordecone-potentiated CHCl3 hepatotoxicity.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Protection of chlordecone-potentiated carbon tetrachloride hepatotoxicity and lethality by partial hepatectomy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Effect of chlordecone and mirex on the acute hepatotoxicity of acetaminophen in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Effect of chlordecone on carbon tetrachloride-induced increase in calcium uptake in isolated perfused rat liver

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Role of hepatocellular regeneration in CCl4 autoprotection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Protection from CCI4 toxicity by prestimulation of hepatocellular regeneration in partially hepatectomized gerbils

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Colchicine Antimitosis Abolishes CCl4 Autoprotection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Potentiation of BrCCl3 hepatotoxicity by chlordecone: Biochemical and ultrastructural study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Role of hepatocellular regeneration and hepatolobular healing in the final outcome of liver injury. A two-stage model of toxicity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

PB-PK derived metabolic constants, hepatotoxicity, and lethality of BrCCl3 in rats pretreated with chlordecone, phenobarbital, or mirex.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Hepatotoxicity and lethality of halomethanes in Mongolian gerbils pretreated with chlordecone, phenobarbital or mirex

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Bromotrichloromethane Hepatotoxicity. The Role of Stimulated Hepatocellular Regeneration in Recovery: Biochemical and Histopathological Studies in Control and Chlordecone Pretreated Male Rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Potentiation of halomethane hepatotoxicity by chlordecone: A hypothesis for the mechanism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Protection from chlordecone-amplified carbon tetrachloride toxicity by cyanidanol: Regeneration studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Protection from chlordecone-amplified carbon tetrachloride toxicity by cyanidanol: Biochemical and histological studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Carbon tetrachloride-induced alterations of hepatic calmodulin and free calcium levels in rats pretreated with chlordecone.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Altered hepatic energy status in chlordecone (kepone®)-potentiated ccl4 hepatotoxicity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Lethal effects of CCl4 and its metabolism by mongolian gerbils pretreated with chlordecone, phenobarbital, or mirex

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Reduction of carbon tetrachloride toxicity by prior administration of a single small dose in mice and rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Ethylene dibromide as a mitogen for liver

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Potentiation of the hepatotoxicity of carbon tetrachloride following preexposure to chlordecone (Kepone) in the male rat

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Kepone: Cellular sites of action

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Acute alteration of chloroform-induced hepato- and nephrotoxicity by mirex and Kepone

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

alpha-Fetoprotein in toxic liver injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Bioactivation of carbon tetrachloride, chloroform and bromotrichloromethane: Role of cytochrome P-450

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Resiliency to amplification of carbon tetrachloride hepatotoxicity by chlordecone during postnatal development in rats.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Resistance to hepatotoxins acquired by hepatocytes during liver regeneration.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Excessive hepatic accumulation of intracellular Ca2+ in chlordecone potentiated CCl4 toxicity

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Destruction of hepatic mixed-function oxygenase parameters by CCl4 in rats following acute treatment with chlordecone, mirex, and phenobarbital

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Potentiation of bromotrichloromethane hepatotoxicity and lethality by chlordecone preexposure in the rat.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

Potentiation of CCl4 hepatotoxicity and lethality by chlordecone in female rats

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

In vivo metabolism of CCl4 by rats pretreated with chlordecone, mirex, or phenobarbital.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566795

2-Propanol treatment induces selectively the metabolism of carbon tetrachloride to phosgene. Implications for carbon tetrachloride hepatotoxicity

25 October 2018

1 reference

12 December 2020

Initiation of the division cycle of rat hepatocytes following a single injection of thioacetamide

1 reference

12 December 2020

CCl4-hepatotoxicity in the Mongolian gerbil: Influence of monooxygenase system induction

1 reference

12 December 2020

Carbon tetrachloride-induced lipid peroxidation: a spin trapping study

1 reference

12 December 2020

Chlordecone-induced potentiation of carbon tetrachloride hepatotoxicity: A morphometric and biochemical study

1 reference

12 December 2020

Correlation of histology and alpha1-fetoprotein resurgence in rat liver regeneration after experimental injury by galactosamine

1 reference

12 December 2020

Liver regeneration after carbon tetrachloride intoxication in the rat

1 reference

12 December 2020

Chlordecone-induced potentiation of carbon tetrachloride hepatotoxicity: A light and electron microscopic study

1 reference

12 December 2020

Comparative renal and hepatotoxicity of halomethanes: bromodichloromethane, bromoform, chloroform, dibromochloromethane and methylene chloride

1 reference

12 December 2020

Evidence for the involvement of organelles in the mechanism of ketone-potentiated chloroform-induced hepatotoxicity

1 reference

12 December 2020

Hepatic regenerative enzyme activity after pericentral and periportal lobular toxic injury

1 reference

12 December 2020

Spin trapping of free radical products of CC14 activation using pulse radiolysis and high energy radiation procedures

1 reference

12 December 2020

Effect of a second CCl 4 -intoxication on CCl 4 -damaged mouse liver

1 reference

12 December 2020

Liver restitution after acute galactosamine hepatitis: autoradiographic and biochemical studies in rats

1 reference

12 December 2020

Rat intrahepatic biliary tract lesions from alpha-naphthyl isothiocyanate

1 reference

12 December 2020

CCl4-induced alterations in Ca++ homeostasis in chlordecone and phenobarbital pretreated animals

1 reference

12 December 2020

Protection of hepatotoxic and lethal effects of CCl4 by partial hepatectomy

1 reference

12 December 2020

Acute changes in the liver after administration of thioacetamide

1 reference

12 December 2020

Amplification of chloroform hepatotoxicity and lethality by dietary chlordecone (kepone) in mice

1 reference

12 December 2020

Hepatic failure toxins depress liver regenerative enzymes after periportal injury with allyl alcohol in the rat

1 reference

12 December 2020

Liver Regeneration in Experimental Carbon Tetrachloride Intoxication

1 reference

12 December 2020

Mechanism of protection against carbon tetrachloride by prior carbon tetrachloride administration

1 reference

12 December 2020

Hyperplasia of bile-ducts induced by alpha-naphthyl-iso-thiocyanate: experimental biliary cirrhosis free from biliary obstruction

1 reference

12 December 2020

Identifiers

DOI

10.1289/EHP.94102S9139

1 reference

5 August 2017

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5 August 2017

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