(Q35034459)

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Methylated DNA binding domain protein 2 (MBD2) coordinately silences gene expression through activation of the microRNA hsa-mir-496 promoter in breast cancer cell line

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29 February 2020

Methylated DNA binding domain protein 2 (MBD2) coordinately silences gene expression through activation of the microRNA hsa-mir-496 promoter in breast cancer cell line (English)

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29 February 2020

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cancer cell line

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Sebastian Alvarado

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29 February 2020

Matthew Suderman

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29 February 2020

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Joanne Wyglinski

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29 February 2020

Stephen A Andrews

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29 February 2020

Moshe Szyf

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29 February 2020

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29 October 2013

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29 February 2020

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29 February 2020

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29 February 2020

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29 February 2020

e74009

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29 February 2020

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29 October 2013

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0 references

DNA 5-methylcytosine demethylation activities of the mammalian DNA methyltransferases

1 reference

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1 reference

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Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer

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DNA methylation regulates MicroRNA expression

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Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome

1 reference

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1 reference

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1 reference

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Aberrant promoter methylation and silencing of the POU2F3 gene in cervical cancer

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Evidence for an instructive mechanism of de novo methylation in cancer cells.

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8 July 2018

TACC3 mediates the association of MBD2 with histone acetyltransferases and relieves transcriptional repression of methylated promoters

1 reference

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Principles of microRNA-target recognition

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Interaction of HTLV-1 Tax and methyl-CpG-binding domain 2 positively regulates the gene expression from the hypermethylated LTR.

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MicroRNA genes are transcribed by RNA polymerase II

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MicroRNAs: small RNAs with a big role in gene regulation

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Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis

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1 reference

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12 December 2020

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based on heuristic

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10.1371/JOURNAL.PONE.0074009

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29 February 2020

2013PLoSO...874009A

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1 reference

Europe PubMed Central

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29 February 2020

1 reference

Europe PubMed Central

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29 February 2020

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