(Q35034984)

5 August 2017

title

Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases (English)

1 reference

5 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21586633

2 December 2024

4

Jitender P Dubey

1 reference

5 August 2017

6

L David Sibley

1 reference

5 August 2017

1

Michael S. Behnke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21586633

2 December 2024

author name string

Asis Khan

2

1 reference

5 August 2017

Keliang Tang

5

1 reference

5 August 2017

John C. Wootton

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21586633

2 December 2024

language of work or name

English

0 references

publication date

17 May 2011

1 reference

full work available at URL

5 August 2017

https://europepmc.org/articles/pmc3111276?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21586633

https://europepmc.org/articles/PMC3111276

2 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21586633

https://europepmc.org/articles/PMC3111276?pdf=render

2 December 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21586633

https://doi.org/10.1073/pnas.1015338108

2 December 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21586633

https://pnas.org/doi/pdf/10.1073/pnas.1015338108

2 December 2024

1 reference

DOI

10.1073/PNAS.1015338108

https://api.crossref.org/works/10.1073/PNAS.1015338108

Proceedings of the National Academy of Sciences of the United States of America

2 December 2024

published in

1 reference

5 August 2017

volume

108

1 reference

5 August 2017

issue

23

1 reference

5 August 2017

page(s)

9631-9636

1 reference

Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

A novel multifunctional oligonucleotide microarray for Toxoplasma gondii

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Toxoplasma rhoptry protein 16 (ROP16) subverts host function by direct tyrosine phosphorylation of STAT6.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Modelling parasite dissemination: host cell subversion and immune evasion by Toxoplasma gondii.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Phenotypic and gene expression changes among clonal type I strains of Toxoplasma gondii

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

A helical membrane-binding domain targets the Toxoplasma ROP2 family to the parasitophorous vacuole

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Selection at a single locus leads to widespread expansion of Toxoplasma gondii lineages that are virulent in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Tagging of endogenous genes in a Toxoplasma gondii strain lacking Ku80

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Novel structural and regulatory features of rhoptry secretory kinases in Toxoplasma gondii

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

ROP2 from Toxoplasma gondii: a virulence factor with a protein-kinase fold and no enzymatic activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Population structure of Toxoplasma gondii: clonal expansion driven by infrequent recombination and selective sweeps

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

The transcription of bradyzoite genes in Toxoplasma gondii is controlled by autonomous promoter elements.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

ToxoDB: an integrated Toxoplasma gondii database resource

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Clustal W and Clustal X version 2.0

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

PAML 4: phylogenetic analysis by maximum likelihood

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Polymorphic secreted kinases are key virulence factors in toxoplasmosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Ocular toxoplasmosis: in the storm of the eye.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Emerging roles of pseudokinases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Migration of Toxoplasma gondii across biological barriers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Identification of quantitative trait loci controlling acute virulence in Toxoplasma gondii

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Transepithelial migration of Toxoplasma gondii is linked to parasite motility and virulence

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Toxoplasma evacuoles: a two-step process of secretion and fusion forms the parasitophorous vacuole

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Median-joining networks for inferring intraspecific phylogenies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Virulent strains of Toxoplasma gondii comprise a single clonal lineage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Quantitative Studies of the Mutagenesis of Toxoplasma gondii

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111276

Recent expansion of Toxoplasma through enhanced oral transmission

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015338108

Production of IL-12 by macrophages infected with Toxoplasma gondii depends on the parasite genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015338108

Oocyst shedding by cats fed isolated bradyzoites and comparison of infectivity of bradyzoites of the VEG strain Toxoplasma gondii to cats and mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21586633

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inverted topology of the Toxoplasma gondii ROP5 rhoptry protein provides new insights into the association of the ROP2 protein family with the parasitophorous vacuole membrane

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21586633

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

28

1 reference

DOI

10.1073/PNAS.1015338108

https://api.crossref.org/works/10.1073/PNAS.1015338108

2 December 2024

Identifiers

DOI

10.1073/PNAS.1015338108

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference