(Q35035524)

5 August 2017

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title

Genetically-engineered bacteria expressing human enzymes and their use in the study of mutagens and mutagenesis (English)

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5 August 2017

P David Josephy

1

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5 August 2017

language of work or name

English

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publication date

1 December 2002

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5 August 2017

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5 August 2017

volume

181-182

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5 August 2017

page(s)

255-260

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Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection

5 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900292-5

7 January 2021

Mutagenicity of nitrosamines in methyltransferase-deficient strains of Salmonella typhimurium coexpressing human cytochrome P450 2E1 and reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900292-5

7 January 2021

Five novel natural allelic variants-951A>C, 1042G>A (D348N), 1156A>T (I386F), 1217G>A (C406Y) and 1291C>T (C431Y)-of the human CYP1A2 gene in a French Caucasian population

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900292-5

7 January 2021

Sulfotransferase-mediated activation of mutagens studied using heterologous expression systems.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900292-5

7 January 2021

Nucleotide sequence of an intronless gene for a human arylamine N-acetyltransferase related to polymorphic drug acetylation

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900292-5

7 January 2021

Expression of human estrogen sulfotransferase in Salmonella typhimurium: differences between hHST and hEST in the enantioselective activation of 1-hydroxyethylpyrene to a mutagen.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900292-5

7 January 2021

Metabolic activation of aromatic amine mutagens by simultaneous expression of human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and N-acetyltransferase in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900292-5

7 January 2021

Activation of MeIQ (2-amino-3,4-dimethylimidazo- [4,5-f]quinoline) by sequence variants of recombinant human cytochrome P450 1A2

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900292-5

7 January 2021

Recombinant human P450 forms 1A1, 1A2, and 1B1 catalyze the bioactivation of heterocyclic amine mutagens in Escherichia coli lacZ strains.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900292-5

7 January 2021

Escherichia coli MTC, a NADPH cytochrome P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450: comparison of three types of expression systems

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900292-5

7 January 2021

Heterologous expression of xenobiotic mammalian-metabolizing enzymes in mutagenicity tester bacteria: an update and practical considerations

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900292-5

7 January 2021

Expression of human cytochrome P450 1A2 in Escherichia coli: a system for biotransformation and genotoxicity studies of chemical carcinogens.

1 reference

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7 January 2021

Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing CYP2E1 or CYP2A6 together with human NADPH-cytochrome P450 reductase.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900292-5

7 January 2021

Dimethylnitrosamine: formation of mutagenic compounds by interaction with mouse liver microsomes.

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7 January 2021

Selection and characterization of human cytochrome P450 1A2 mutants with altered catalytic properties

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7 January 2021

Human glutathione S-transferase-expressing Salmonella typhimurium tester strains to study the activation/detoxification of mutagenic compounds: studies with halogenated compounds, aromatic amines and aflatoxin B1.

1 reference

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7 January 2021

Expression of mammalian glutathione S-transferase 5-5 in Salmonella typhimurium TA1535 leads to base-pair mutations upon exposure to dihalomethanes

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7 January 2021

New tester strains of Salmonella typhimurium highly sensitive to mutagenic nitroarenes

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https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900292-5

7 January 2021

Metabolic activation of heterocyclic aromatic amines catalyzed by human arylamine N-acetyltransferase isozymes (NAT1 and NAT2) expressed in Salmonella typhimurium.

1 reference

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7 January 2021

Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity

1 reference

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7 January 2021

Rate-determining steps in phenacetin oxidations by human cytochrome P450 1A2 and selected mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900292-5

7 January 2021

10.1016/S0300-483X(02)00292-5

Identifiers

DOI

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5 August 2017

1 reference