(Q35036585)

5 August 2017

1 reference

title

Human papillomavirus-induced carcinogenesis and the ubiquitin-proteasome system (English)

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ubiquitin-proteasome system

5 August 2017

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1

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5 August 2017

Noel J Whitaker

2

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5 August 2017

1 February 2003

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Seminars in Cancer Biology

5 August 2017

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5 August 2017

13

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5 August 2017

59-67

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5 August 2017

1

1 reference

A novel class of herpesvirus-encoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Kaposi's sarcoma-associated herpesvirus encodes two proteins that block cell surface display of MHC class I chains by enhancing their endocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Downregulation of major histocompatibility complex class I molecules by Kaposi's sarcoma-associated herpesvirus K3 and K5 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

A role for ubiquitin ligase recruitment in retrovirus release

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Ubiquitin is part of the retrovirus budding machinery

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

The human papillomavirus E6 protein and its contribution to malignant progression

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Biological activities and molecular targets of the human papillomavirus E7 oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Epidermal cancer associated with expression of human papillomavirus type 16 E6 and E7 oncogenes in the skin of transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Association of human papillomavirus types 16 and 18 E6 proteins with p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV type 16 E7-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

The regulation of E2F by pRB-family proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

The human papillomavirus type 16 E7 oncogene is required for the productive stage of the viral life cycle

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Regions of human papillomavirus type 16 E7 oncoprotein required for immortalization of human keratinocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

A mutational analysis of the amino terminal domain of the human papillomavirus type 16 E7 oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Comparison of the properties of the E6 and E7 genes of low- and high-risk cutaneous papillomaviruses reveals strongly transforming and high Rb-binding activity for the E7 protein of the low-risk human papillomavirus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Destabilization of the retinoblastoma tumor suppressor by human papillomavirus type 16 E7 is not sufficient to overcome cell cycle arrest in human keratinocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Induction of pRb degradation by the human papillomavirus type 16 E7 protein is essential to efficiently overcome p16INK4a-imposed G1 cell cycle Arrest

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

The human papillomavirus E7 oncoprotein functionally interacts with the S4 subunit of the 26 S proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Gankyrin is an ankyrin-repeat oncoprotein that interacts with CDK4 kinase and the S6 ATPase of the 26 S proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Degradation of the E7 human papillomavirus oncoprotein by the ubiquitin-proteasome system: targeting via ubiquitination of the N-terminal residue

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Human papillomavirus life cycle: active and latent phases

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Mutational analysis of human papillomavirus type 16 E6 demonstrates that p53 degradation is necessary for immortalization of mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Human papillomavirus type 16 E6-induced degradation of E6TP1 correlates with its ability to immortalize human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

IARC Database of p53 gene mutations in human tumors and cell lines: updated compilation, revised formats and new visualisation tools

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Cellular responses of HPV-positive cancer cells to genotoxic anti-cancer agents: repression of E6/E7-oncogene expression and induction of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

A comparative analysis of the interactions of the E6 proteins from cutaneous and genital papillomaviruses with p53 and E6AP in correlation to their transforming potential

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Ubiquitin, E6-AP, and their role in p53 inactivation.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Antisense targeting of E6AP elevates p53 in HPV-infected cells but not in normal cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Characterization of sequence elements involved in p53 stability regulation reveals cell type dependence for p53 degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Elevated wild-type p53 protein levels in human epithelial cell lines immortalized by the human papillomavirus type 16 E7 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Analysis of the p53-mediated G1 growth arrest pathway in cells expressing the human papillomavirus type 16 E7 oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

The adenovirus E4orf6 protein can promote E1A/E1B-induced focus formation by interfering with p53 tumor suppressor function

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

VHL: a very hip ligase

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Characterization of Human hect Domain Family Members and Their Interaction with UbcH5 and UbcH7

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

A very large protein with diverse functional motifs is deficient in rjs (runty, jerky, sterile) mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

The spectrum of mutations in UBE3A causing Angelman syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitination.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Inhibition of Bak-induced apoptosis by HPV-18 E6.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

E3-ubiquitin ligase/E6-AP links multicopy maintenance protein 7 to the ubiquitination pathway by a novel motif, the L2G box

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Human papillomavirus (HPV) E6 interactions with Bak are conserved amongst E6 proteins from high and low risk HPV types

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Role of Bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

PDZ domains: More than just a glue

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

HPV E6 targeted degradation of the discs large protein: evidence for the involvement of a novel ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Human papillomavirus types 16 E6 and E7 contribute differently to carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

Induction of apoptosis in human papillomaviruspositive cancer cells by peptide aptamers targeting the viral E6 oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900100-1

7 January 2021

10.1016/S1044-579X(02)00100-1

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12507557