(Q35037741)

5 August 2017

1 reference

title

Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties (English)

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5 August 2017

Rupprecht R

1

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5 August 2017

publication date

1 February 2003

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5 August 2017

published in

Psychoneuroendocrinology

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5 August 2017

volume

28

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5 August 2017

issue

2

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5 August 2017

page(s)

139-168

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Neurosteroid metabolism. 7 alpha-Hydroxylation of dehydroepiandrosterone and pregnenolone by rat brain microsomes

5 August 2017

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Dehydroepiandrosterone functions as more than an antiglucocorticoid in preserving immunocompetence after thermal injury

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7 January 2021

The effect of dehydroepiandrosterone sulfate administration to patients with multi-infarct dementia.

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7 January 2021

Clozapine, but not haloperidol, increases brain concentrations of neuroactive steroids in the rat.

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7 January 2021

Influence of neurosteroids on the development of rapid tolerance to ethanol in mice

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7 January 2021

Nongenomic effects of steroids on the nicotinic acetylcholine receptor

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7 January 2021

Endogenous levels of dehydroepiandrosterone sulfate, but not other sex hormones, are associated with depressed mood in older women: the Rancho Bernardo Study

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7 January 2021

Neurosteroids: a new function in the brain

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7 January 2021

Neurosteroids: a novel function of the brain.

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7 January 2021

Effects of intravenous progesterone infusions on the epileptic discharge frequency in women with partial epilepsy

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7 January 2021

Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride ionophore complex

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7 January 2021

Allopregnanolone and dehydroepiandrosterone response to corticotropin-releasing factor in patients suffering from Alzheimer's disease and vascular dementia.

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7 January 2021

Serum concentrations of some neuroactive steroids in women suffering from mixed anxiety-depressive disorder.

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7 January 2021

Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

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7 January 2021

Anxiolytic Effect of Progesterone is Mediated by the Neurosteroid Allopregnanolone at Brain GABAA Receptors

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7 January 2021

Dehydroepiandrosterone regulation of the hepatic glucocorticoid receptor in the Zucker rat. The obesity research program

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7 January 2021

Neurosteroids modulate nicotinic receptor function in mouse striatal and thalamic synaptosomes

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7 January 2021

Pregnanolone emulsion. A preliminary pharmacokinetic and pharmacodynamic study of a new intravenous anaesthetic agent.

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7 January 2021

Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor

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7 January 2021

Neurosteroids: biosynthesis and function of these novel neuromodulators

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7 January 2021

Role of brain allopregnanolone in the plasticity of gamma-aminobutyric acid type A receptor in rat brain during pregnancy and after delivery.

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7 January 2021

Anxiolytic activity of an endogenous adrenal steroid.

1 reference

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7 January 2021

The influence of subchronic administration of the neurosteroid allopregnanolone on sleep in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

The 5-HT3B subunit is a major determinant of serotonin-receptor function

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

The neurosteroid, 3 alpha-hydroxy-5 alpha-pregnan-20-one, protects against bicuculline-induced seizures during ethanol withdrawal in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Brain 5alpha-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one modulates electrophysiological and behavioral actions of ethanol.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

The steroid and thyroid hormone receptor superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Endogenous concentrations of DHEA and DHEA-S decrease with remission of depression in older adults

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Memory-enhancing effects in male mice of pregnenolone and steroids metabolically derived from it.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Dehydroepiandrosterone and its sulfate enhance memory retention in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Progesterone-induced changes in sleep in male subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Progesterone metabolites, effective at the GABAA receptor complex, attenuate pain sensitivity in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Neuroactive steroids: potential therapeutic use in neurological and psychiatric disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Inhibition of oxytocin receptor function by direct binding of progesterone

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

3alpha-hydroxy-5alpha-pregnan-20-one exposure reduces GABA(A) receptor alpha4 subunit mRNA levels.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

1 reference

7 January 2021

Selective oestrogen receptor modulators--current and future brain and behaviour applications

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Variation in symptom severity over the menstrual cycle of schizophrenics.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Generating and testing a causal explanation of the gender difference in age at first onset of schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Pharmacological characterisation of cortical gamma-aminobutyric acid type A (GABAA) receptors in two Wistar rat lines selectively bred for high and low anxiety-related behaviour.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Progesterone therapy in women with complex partial and secondary generalized seizures.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Increased diurnal plasma concentrations of dehydroepiandrosterone in depressed patients

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

DHEA-S plasma levels and incidence of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Dehydroepiandrosterone (DHEA) supplementation for cognition and well-being

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Antidepressant-like effect of the neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one in mice forced swim test.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Allopregnanolone (THP) mediates anesthetic effects of progesterone in rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Increased behavioral neurosteroid sensitivity in a rat line selectively bred for high alcohol sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

A clinical trial of the effects of estrogen in acutely psychotic women

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Estrogen - a potential treatment for schizophrenia.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Prolonged intracerebroventricular infusion of neurosteroids affects cognitive performances in the mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Neurosteroids and GABAA receptor function.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Progesterone induces changes in sleep comparable to those of agonistic GABAA receptor modulators.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

The GABA(A) receptor antagonist picrotoxin attenuates most sleep changes induced by progesterone.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Sensitivity to CCK-4 in women with and without premenstrual dysphoric disorder (PMDD) during their follicular and luteal phases.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Basal plasma dehydroepiandrosterone sulfate level: a possible predictor for response to electroconvulsive therapy in depressed psychotic inpatients.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Modulation of GABA(A) receptor function by neuroactive steroids: evidence for heterogeneity of steroid sensitivity of recombinant GABA(A) receptor isoforms.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Subunit dependent modulation of GABAA receptor function by neuroactive steroids.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Olanzapine increases allopregnanolone in the rat cerebral cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Non-genomic and genomic effects of steroids on neural activity

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Sleep induction by an adrenal steroid in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Antidepressant-like actions of pregnancy, and progesterone in Wistar rats forced to swim

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Ganaxolone: a novel positive allosteric modulator of the GABA(A) receptor complex for the treatment of epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Initial human experience with ganaxolone, a neuroactive steroid with antiepileptic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Neurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Relationships between cortisol, dehydroepiandrosterone sulphate and insulin-like growth factor-I system in dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Antinociceptive properties of neurosteroids III: experiments with alphadolone given intravenously, intraperitoneally, and intragastrically

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Serum dehydroepiandrosterone sulfate in Alzheimer's disease and in multi-infarct dementia.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Salivary cortisol and DHEA: association with measures of cognition and well-being in normal older men, and effects of three months of DHEA supplementation

1 reference

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7 January 2021

A corticosteroid receptor in neuronal membranes.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Membrane estrogen receptors identified by multiple antibody labeling and impeded-ligand binding.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Neonatal treatment of rats with the neuroactive steroid tetrahydrodeoxycorticosterone (THDOC) abolishes the behavioral and neuroendocrine consequences of adverse early life events

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

The neurosteroid tetrahydroprogesterone counteracts corticotropin-releasing hormone-induced anxiety and alters the release and gene expression of corticotropin-releasing hormone in the rat hypothalamus

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

5β-Pregnan-3β-ol-20-one, a specific antagonist at the neurosteroid site of the GABAA receptor-complex

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Neurosteroids act on recombinant human GABAA receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Membrane sex-steroid receptors in the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Progesterone metabolite allopregnanolone in women with premenstrual syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Neuroactive steroid-serotonergic interaction: responses to an intravenous L-tryptophan challenge in women with premenstrual syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Neurosteroids act on the GABA(A) receptor at sites on the N-terminal side of the middle of TM2.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Marked decrease of plasma neuroactive steroids during alcohol withdrawal.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Effects of fluoxetine, indomethacine and placebo on 3 alpha, 5 alpha tetrahydroprogesterone (THP) plasma levels in uncomplicated alcohol withdrawal.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Effects of antidepressant treatment on neuroactive steroids in major depression

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

The neuropsychopharmacological potential of neuroactive steroids

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Steroid receptor-mediated effects of neuroactive steroids: characterization of structure-activity relationship

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Assessment of neuroleptic-like properties of progesterone.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Progesterone receptor-mediated effects of neuroactive steroids

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Soporific effect of the neurosteroid pregnanolone in relation to the substance's plasma level: a pilot study.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Steroidogenesis in rat brain induced by short- and long-term administration of carbamazepine

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Opposite effects of short- versus long-term administration of fluoxetine on the concentrations of neuroactive steroids in rat plasma and brain

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

GABA(A) receptor alpha4 subunit suppression prevents withdrawal properties of an endogenous steroid.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Withdrawal from 3alpha-OH-5alpha-pregnan-20-One using a pseudopregnancy model alters the kinetics of hippocampal GABAA-gated current and increases the GABAA receptor alpha4 subunit in association with increased anxiety.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Influence of membrane cholesterol on modulation of the GABA(A) receptor by neuroactive steroids and other potentiators

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Fluoxetine in the treatment of premenstrual dysphoria. Canadian Fluoxetine/Premenstrual Dysphoria Collaborative Study Group.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Fluoxetine decreases concentrations of 3 alpha, 5 alpha-tetrahydrodeoxycorticosterone (THDOC) in major depression.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

GABA(A) receptor-modulating neuroactive steroid composition in patients with panic disorder before and during paroxetine treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Concentrations of 3 alpha-reduced neuroactive steroids and their precursors in plasma of patients with major depression and after clinical recovery.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Steroid binding at sigma receptors suggests a link between endocrine, nervous, and immune systems

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Reduced plasma dehydroepiandrosterone concentrations in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Citalopram increases pregnanolone sensitivity in patients with premenstrual syndrome: an open trial.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

A new wave of serotonin receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Progesterone modulates a neuronal nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Neurosteroids: deficient cognitive performance in aged rats depends on low pregnenolone sulfate levels in the hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Neuroprotective activity of a new class of steroidal inhibitors of the N-methyl-D-aspartate receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

17beta-Estradiol protects against NMDA-induced excitotoxicity by direct inhibition of NMDA receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Specific, nongenomic actions of steroid hormones

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Functional antagonism of gonadal steroids at the 5-hydroxytryptamine type 3 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Anxiolytic activity of the progesterone metabolite 5α-pregnan-3α-ol-20-one

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Opposing effects of DHEA replacement in elderly subjects on declarative memory and attention after exposure to a laboratory stressor.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

Dehydroepiandrosterone (DHEA) treatment of depression

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

The effects of steroid hormones on electrical activity of excitable cells

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4530%2802%2900064-1

7 January 2021

10.1016/S0306-4530(02)00064-1

Identifiers

DOI

1 reference

5 August 2017

1 reference