(Q35038056)

5 August 2017

1 reference

title

Pharmacogenetics in drug development (English)

1 reference

5 August 2017

Alun D McCarthy

1

1 reference

5 August 2017

James L Kennedy

series ordinal

2

1 reference

5 August 2017

Lefkos T Middleton

series ordinal

3

1 reference

5 August 2017

language of work or name

English

0 references

publication date

1 August 2005

1 reference

5 August 2017

number of pages

10

1 reference

Philosophical Transactions of the Royal Society B

inferred from page(s)

published in

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5 August 2017

volume

360

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5 August 2017

issue

1460

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5 August 2017

page(s)

1579-1588

1 reference

Disease-specific target selection: a critical first step down the right road

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Pharmacogenetics and drug development: the path to safer and more effective drugs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Translation of pharmacogenomics and pharmacogenetics: a regulatory perspective

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Serotonin transporter: gene, genetic disorders, and pharmacogenetics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Medical genetics: a marker for Stevens-Johnson syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Protein kinase inhibitors: insights into drug design from structure.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Molecular signatures for diagnosis of infection: application of microarray technology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Functional neuroimaging of genetic variation in serotonergic neurotransmission

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Pharmacogenetics goes genomic

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Clinical Experience with Trastuzumab (Herceptin)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Effect of DRD2, 5-HT2A, and COMT genes on antipsychotic response to risperidone.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Human drug metabolising cytochrome P450 enzymes: properties and polymorphisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Pharmacophylogenomics: genes, evolution and drug targets

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Pharmacogenetics and Pharmacogenomics in Drug Development and Regulatory Decision Making: Report of the First FDA‐PWG‐PhRMA‐DruSafe Workshop

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Integrated approaches to therapeutic target gene discovery

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

The price of innovation: new estimates of drug development costs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Pharmacogenetics of the major polymorphic metabolizing enzymes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Genome-based pharmacogenetics and the pharmaceutical industry

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Genetic variations in HLA-B region and hypersensitivity reactions to abacavir

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Implications of the human genome for understanding human biology and medicine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Culture and psychopharmacology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Genomic control for association studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

The impact of genomics on drug discovery

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Use of unlinked genetic markers to detect population stratification in association studies.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Impact of genetic polymorphisms of the beta2-adrenergic receptor on albuterol bronchodilator pharmacodynamics.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Association between genetic polymorphisms of the beta2-adrenoceptor and response to albuterol in children with and without a history of wheezing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Dopamine D3-receptor gene variant and susceptibility to tardive dyskinesia in schizophrenic patients

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

The evolving science of pharmacogenetics: clinical and ethnic perspectives.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Association of the MscI polymorphism of the dopamine D3 receptor gene with tardive dyskinesia in schizophrenia

8 July 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1688

Broadly altered gene expression in blood leukocytes in essential hypertension is absent during treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1688

Beta(2)-adrenoceptor polymorphism determines vascular reactivity in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1688

A Gilbert's syndrome UGT1A1 variant confers susceptibility to tranilast-induced hyperbilirubinemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1688

The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1688

A common polymorphism of the growth hormone receptor is associated with increased responsiveness to growth hormone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1688

Change from the CYP2D6 extensive metabolizer to the poor metabolizer phenotype during treatment With bupropion

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1688

Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1688

Association between angiotensin-converting enzyme gene polymorphisms and regression of left ventricular hypertrophy in patients treated with angiotensin-converting enzyme inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1688

Pharmacogenetics of tardive dyskinesia: combined analysis of 780 patients supports association with dopamine D3 receptor gene Ser9Gly polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1688

The role of serotonin transporter protein gene in antidepressant-induced mania in bipolar disorder: preliminary findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1688

CYP2D6 genotype: impact on adverse effects and nonresponse during treatment with antidepressants-a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1688

Towards molecular medicine; reminiscences of the haemoglobin field, 1960-2000.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2005.1688

Pharmacogenetic analysis of the effect of angiotensin-converting enzyme inhibitor on restenosis after percutaneous transluminal coronary angioplasty

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569527

Use of liquid chromatography/time-of-flight mass spectrometry and multivariate statistical analysis shows promise for the detection of drug metabolites in biological fluids

25 October 2018

1 reference

12 December 2020

Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment

1 reference

12 December 2020

Relationship between the response to the angiotensin converting enzyme inhibitor imidapril and the angiotensin converting enzyme genotype

1 reference

12 December 2020

Angiotensin converting enzyme gene polymorphism and ACE inhibition in diabetic nephropathy

1 reference

12 December 2020

Effect of angiotensin-converting enzyme (ACE) gene polymorphism on progression of renal disease and the influence of ACE inhibition in IDDM patients: findings from the EUCLID Randomized Controlled Trial. EURODIAB Controlled Trial of Lisinopril in ID

1 reference

12 December 2020

Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine

1 reference

12 December 2020

Identifiers

DOI

10.1098/RSTB.2005.1688

1 reference

5 August 2017

1 reference

5 August 2017

1 reference