(Q35038687)

5 August 2017

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title

The mitochondrial theory of aging: involvement of mitochondrial DNA damage and repair (English)

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5 August 2017

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2

Vilhelm A Bohr

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5 August 2017

author name string

Nadja C de Souza-Pinto

series ordinal

1

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5 August 2017

publication date

1 January 2002

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International Review of Neurobiology

5 August 2017

published in

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5 August 2017

volume

53

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5 August 2017

page(s)

519-534

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Aging and proteolysis of oxidized proteins

5 August 2017

cites work

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Mitochondrial endogenous oxidative damage has been overestimated

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Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging?

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Low mitochondrial free radical production per unit O2 consumption can explain the simultaneous presence of high longevity and high aerobic metabolic rate in birds.

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Protection of DNA damage by dietary restriction

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An oxidative damage-specific endonuclease from rat liver mitochondria.

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A putative gene causes variability in lifespan among genotypically identical mice

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7 January 2021

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7 January 2021

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Mutagenesis by 8-oxoguanine: an enemy within

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Nucleotide excision repair of actively transcribed versus nontranscribed DNA in rat hepatocytes: effect of age and dietary restriction

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7 January 2021

Aging: a theory based on free radical and radiation chemistry

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7 January 2021

The biologic clock: the mitochondria?

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7 January 2021

Regulation of expression of nuclear and mitochondrial forms of human uracil-DNA glycosylase

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7 January 2021

Age-associated damage in mitochondrial DNA in human hearts

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7 January 2021

Quantification of oxidative DNA modifications in mitochondria.

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Purification of all forms of HeLa cell mitochondrial DNA and assessment of damage to it caused by hydrogen peroxide treatment of mitochondria or cells.

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7 January 2021

Age-associated change in mitochondrial DNA damage.

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7 January 2021

NMR structural studies of the ionizing radiation adduct 7-hydro-8-oxodeoxyguanosine (8-oxo-7H-dG) opposite deoxyadenosine in a DNA duplex. 8-Oxo-7H-dG(syn).dA(anti) alignment at lesion site

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7 January 2021

DNA glycosylases in the base excision repair of DNA

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7 January 2021

Comparison of mitochondrial pro-oxidant generation and anti-oxidant defenses between rat and pigeon: possible basis of variation in longevity and metabolic potential

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7 January 2021

The human DNA ligase III gene encodes nuclear and mitochondrial proteins

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7 January 2021

Repair of mitochondrial DNA after various types of DNA damage in Chinese hamster ovary cells

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7 January 2021

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7 January 2021

Crystal structure of a DNA duplex containing 8-hydroxydeoxyguanine-adenine base pairs

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7 January 2021

Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication

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7 January 2021

Mitochondrial role in cell aging

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7 January 2021

Mutagenesis by hydrogen peroxide treatment of mammalian cells: a molecular analysis

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7 January 2021

Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene

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7 January 2021

Age-dependent decline in the cytochrome c oxidase activity in rat heart mitochondria: role of cardiolipin

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7 January 2021

The rate of free radical production as a determinant of the rate of aging: evidence from the comparative approach

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Mitochondrial DNA damage by anticancer agents

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7 January 2021

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7 January 2021

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7 January 2021

Age-associated increase in 8-oxo-deoxyguanosine glycosylase/AP lyase activity in rat mitochondria

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7 January 2021

DNA repair and aging in mouse liver: 8-oxodG glycosylase activity increase in mitochondrial but not in nuclear extracts

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7 January 2021

Cytotoxicity and metabolism of 4-hydroxy-2-nonenal and 2-nonenal in H2O2-resistant cell lines. Do aldehydic by-products of lipid peroxidation contribute to oxidative stress?

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7 January 2021

Protein oxidation and aging

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7 January 2021

Single-nucleotide patch base excision repair of uracil in DNA by mitochondrial protein extracts

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7 January 2021

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7 January 2021

Mitochondrial targeting of human DNA glycosylases for repair of oxidative DNA damage

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7 January 2021

Age-associated damage in mitochondrial function in rat hearts

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7 January 2021

Garbage catastrophe theory of aging: imperfect removal of oxidative damage?

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7 January 2021

Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice

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7 January 2021

Nucleotide excision repair in mammalian cells

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7 January 2021

Comparison of Oxidative Base Damage in Mitochondrial and Nuclear DNA

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7 January 2021

8-oxo-deoxyguanosine levels in heart and brain mitochondrial and nuclear DNA of two mammals and three birds in relation to their different rates of aging

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7 January 2021

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Identifiers

DOI

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5 August 2017

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