(Q35039136)

5 August 2017

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title

Differential pharmacokinetics of theophylline in elderly patients (English)

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5 August 2017

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Akihiro Ohnishi

1

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5 August 2017

Motokazu Kato

2

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5 August 2017

Jun Kojima

3

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5 August 2017

Hideki Ushiama

4

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5 August 2017

Maki Yoneko

5

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5 August 2017

Hiroyuki Kawai

6

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5 August 2017

publication date

1 January 2003

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5 August 2017

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5 August 2017

volume

20

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5 August 2017

issue

1

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5 August 2017

page(s)

71-84

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Aging and drug interactions. II. Effect of phenytoin and smoking on the oxidation of theophylline and cortisol in healthy men

5 August 2017

cites work

1 reference

12 December 2020

Drug interactions and the cytochrome P450 system. The role of cytochrome P450 1A2.

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12 December 2020

Kinetics and efficacy of theophylline in the treatment of apnea in the premature newborn

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12 December 2020

Life-threatening events after theophylline overdose: a 10-year prospective analysis

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12 December 2020

Theophylline. A review of its potential steroid sparing effects in asthma

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12 December 2020

Bioavailability and pharmacokinetics of theophylline in plain uncoated and sustained-release dosage forms in relation to smoking habit. I. Single dose study

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12 December 2020

Theophylline pharmacokinetics in premature infants with apnea

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12 December 2020

Method for the rapid estimation of the total body drug clearance and adjustment of dosage regimens in patients during a constant-rate intravenous infusion

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12 December 2020

Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1

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12 December 2020

Quantitative liver function in the elderly assessed by galactose elimination capacity, aminopyrine demethylation and caffeine clearance

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12 December 2020

New synthetic quinolone antibacterial agents and serum concentration of theophylline

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12 December 2020

The aging liver. Drug clearance and an oxygen diffusion barrier hypothesis.

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12 December 2020

A Clinical and Pharmacokinetic Basis for the Selection and Use of Slow Release Theophylline Products

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12 December 2020

Theophylline pharmacokinetics in normal elderly subjects

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12 December 2020

Anti-inflammatory effects of low-dose oral theophylline in atopic asthma

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12 December 2020

Theophylline induces a reduction in circulating interleukin-4 and interleukin-5 in atopic asthmatics

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12 December 2020

Long acting beta(2) agonists and theophylline in stable chronic obstructive pulmonary disease

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12 December 2020

Rational Intravenous Doses of Theophylline

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12 December 2020

Genetic polymorphism in the 5'-flanking region of human CYP1A2 gene: effect on the CYP1A2 inducibility in humans

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12 December 2020

Intraindividual variability in theophylline pharmacokinetics: statistical verification in 39 of 60 healthy young adults

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12 December 2020

Macrolide antibacterials. Drug interactions of clinical significance

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12 December 2020

Cigarette smoking and theophylline metabolism: effects of cimetidine

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12 December 2020

The influence of cigarette smoking and sex on theophylline disposition

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12 December 2020

Plasma xanthine levels in low birthweight infants treated or not treated with theophylline

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12 December 2020

Effect of a 4-week treatment with theophylline on sputum eosinophilia and sputum eosinophil chemotactic activity in steroid-naive asthmatics

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12 December 2020

[Guidelines for the diagnosis and management of bronchial asthma--a comparison of the Japanese guidelines for the adult asthma with GINA and ICR]

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12 December 2020

Effects of dietary broccoli on human drug metabolising activity.

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12 December 2020

Nonlinear pharmacokinetics: clinical Implications

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12 December 2020

Effect of cruciferous vegetable consumption on heterocyclic aromatic amine metabolism in man.

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12 December 2020

Midazolam kinetics in women of two age groups

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12 December 2020

Theophylline inhibits early and late asthmatic reactions induced by allergens in asthmatic subjects

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12 December 2020

Pharmacokinetic optimisation of asthma treatment

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12 December 2020

Effects of passive smoking on theophylline clearance

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12 December 2020

Effect of combination therapy with ciprofloxacin and clarithromycin on theophylline pharmacokinetics in healthy volunteers.

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12 December 2020

Sleep and aminophylline treatment of apnea in preterm infants

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12 December 2020

Theophylline-associated seizures with "therapeutic" or low toxic serum concentrations: Risk factors for serious outcome in adults

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12 December 2020

Time to steady state following a change in dosing rate.

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12 December 2020

Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects

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12 December 2020

A review of clinical use of theophylline in acute asthma: factors influencing kinetic disposition and drug interactions.

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12 December 2020

Intraindividual changes in theophylline clearance during constant aminophylline infusion in children with acute asthma

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12 December 2020

The effect of maintenance theophylline therapy on lung work in severe chronic obstructive pulmonary disease while standing and walking

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12 December 2020

Aging and the response to inhibition and induction of theophylline metabolism

1 reference

12 December 2020

Nonlinear theophylline pharmacokinetics. A preventable cause of iatrogenic theophylline toxic reactions

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12 December 2020

Age and cytochrome P450-linked drug metabolism in humans: an analysis of 226 subjects with equal histopathologic conditions

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12 December 2020

Effects of theophylline on diaphragmatic strength and fatigue in patients with chronic obstructive pulmonary disease

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12 December 2020

Dose dependent pharmacokinetics of theophylline: Michaelis-Menten parameters for its major metabolic pathways

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12 December 2020

Simultaneous determinations by theophylline and its major metabolites in urine by reversed-phase ion-pair high-performance liquid chromatography

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12 December 2020

Cimetidine impairs the elimination of theophylline and antipyrine

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12 December 2020

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12 December 2020

Use of a pharmacologic indicator to compare compliance with tablets prescribed to be taken once, twice, or three times daily.

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12 December 2020

The effect of theophylline on blood and sputum eosinophils and ECP in patients with bronchial asthma

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12 December 2020

Asthma therapy: theophylline

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12 December 2020

Factors affecting theophylline clearances: Age, tobacco, marijuana, cirrhosis, congestive heart failure, obesity, oral contraceptives, benzodiazepines, barbiturates, and ethanol

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12 December 2020

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12 December 2020

Aging and the liver: an update

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12 December 2020

Development of a radioimmunoassay for theophylline; Application to studies in premature infants

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12 December 2020

Multiple mechanisms of xanthine actions on airway reactivity

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12 December 2020

Theophylline kinetics in acute pulmonary edema

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12 December 2020

Factors affecting theophylline pharmacokinetics in premature infants with apnea

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12 December 2020

Pharmacokinetics of terfenadine in healthy elderly subjects

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12 December 2020

Risk of toxicity in patients with elevated theophylline levels

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12 December 2020

Theophylline N-demethylations as probes for P4501A1 and P4501A2.

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12 December 2020

Pharmacokinetics of theophylline in infants with bronchiolitis

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12 December 2020

Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites.

1 reference

12 December 2020

Functional significance of a C-->A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine

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12 December 2020

Theophylline and airway inflammation

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12 December 2020

Induction of theophylline clearance by rifampin and rifabutin in healthy male volunteers.

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12 December 2020

Development and application of a simple microassay for adenosine in rat plasma

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12 December 2020

Theophylline A “State of the Art” Review

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12 December 2020

Usefulness and safety of theophylline injection form (Theodrip) for the treatment of acute asthma

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12 December 2020

Intraindividual variability in theophylline pharmacokinetics in subjects with mild/moderate asthma

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12 December 2020

Pharmacokinetic study of theophylline in dogs after intravenous administration with and without ethylenediamine

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12 December 2020

Theophylline in the management of asthma: time for reappraisal?

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12 December 2020

Effects of time of dose in relation to food on the bioavailability of Theo-Dur Sprinkle at steady state in asthmatic children

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12 December 2020

Theophylline--an immunomodulatory role in asthma?

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12 December 2020

Mechanism of interaction between theophylline and mexiletine.

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12 December 2020

Theophylline disposition in acutely ill hospitalized patients. The effect of smoking, heart failure, severe airway obstruction, and pneumonia.

1 reference

12 December 2020

The effect of theophylline and enprofylline on allergen-induced bronchoconstriction.

1 reference

12 December 2020

Aging and drug interactions. III. Individual and combined effects of cimetidine and cimetidine and ciprofloxacin on theophylline metabolism in healthy male and female nonsmokers.

1 reference

12 December 2020

Bioavailability and pharmacokinetics of theophylline following plain uncoated and sustained-release dosage forms in relation to smoking habit. II. Multiple dose study

1 reference

12 December 2020

Characterization of human liver cytochromes P-450 involved in theophylline metabolism

1 reference

12 December 2020

Pharmacokinetic aspects of theophylline in premature newborns

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12 December 2020

Dosage schedule for intravenous aminophylline in apnoea of prematurity, based on pharmacokinetic studies

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12 December 2020

Detection of three genetic polymorphisms in the 5'-flanking region and intron 1 of human CYP1A2 in the Japanese population.

1 reference

12 December 2020

Phenotyping of CYP1A2 in Japanese population by analysis of caffeine urinary metabolites: absence of mutation prescribing the phenotype in the CYP1A2 gene

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12 December 2020

Update on rifampin drug interactions, III.

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12 December 2020

10.2165/00002512-200320010-00005

Identifiers

DOI

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Dimensions Publication ID

5 August 2017

1049619962

0 references

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