(Q35045424)

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A phase 1b randomized, controlled, double-blinded dosage-escalation trial to evaluate the safety, reactogenicity and immunogenicity of an adenovirus type 35 based circumsporozoite malaria vaccine in Burkinabe healthy adults 18 to 45 years of age

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Europe PubMed Central

PubMed publication ID

6 August 2017

A phase 1b randomized, controlled, double-blinded dosage-escalation trial to evaluate the safety, reactogenicity and immunogenicity of an adenovirus type 35 based circumsporozoite malaria vaccine in Burkinabe healthy adults 18 to 45 years of age (English)

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6 August 2017

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malaria vaccine

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Sodiomon B Sirima

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Sodiomon B Sirima

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6 August 2017

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Jerald Sadoff

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6 August 2017

Edith C Bougouma

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Edith C Bougouma

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Amidou Diarra

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Alfred B Tiono

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Alphonse Ouédraogo

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Alphonse Ouédraogo

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Issiaka Soulama

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Issiaka Soulama

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Amadou T. Konaté

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Amadou T Konate

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Jean Baptiste Yaro

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Jean Baptiste Yaro

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Souleymane Sanon

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Souleymane Sanon

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Youssouf Kaboré

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Youssouf Kaboré

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Adama Gansane

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Désiré Kargougou

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Esperance Ouédraogo

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David Kangoye

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Noelie Henri

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Nora L Watson

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Valerie Brown

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Jenny Hendriks

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Maria Grazia Pau

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Isabella Versteege

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Edison Wiesken

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Issa Nebie

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11 November 2013

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6 August 2017

e78679

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6 August 2017

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Creative Commons Attribution 4.0 International

11 November 2013

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April 2022 Public Data File from Crossref

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Update on the clinical development of candidate malaria vaccines.

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8 July 2018

Adenovirus types 5 and 35 seroprevalence in AIDS risk groups supports type 35 as a vaccine vector

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8 July 2018

Prevalence of neutralizing antibodies to adenoviral serotypes 5 and 35 in the adult populations of The Gambia, South Africa, and the United States

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Quantifying Adenovirus-Neutralizing Antibodies by Luciferase Transgene Detection: Addressing Preexisting Immunity to Vaccine and Gene Therapy Vectors

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Replication-deficient human adenovirus type 35 vectors for gene transfer and vaccination: efficient human cell infection and bypass of preexisting adenovirus immunity

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The binding of the circumsporozoite protein to cell surface heparan sulfate proteoglycans is required for plasmodium sporozoite attachment to target cells.

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25 October 2018

Identifiers

10.1371/JOURNAL.PONE.0078679

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Europe PubMed Central

PubMed publication ID

6 August 2017

2013PLoSO...878679O

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Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

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Europe PubMed Central

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6 August 2017

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