(Q35047156)

6 August 2017

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title

Sphingosine in apoptosis signaling (English)

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6 August 2017

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Olivier Cuvillier

1

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6 August 2017

language of work or name

English

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publication date

1 December 2002

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Biochimica et Biophysica Acta

6 August 2017

published in

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6 August 2017

volume

1585

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6 August 2017

issue

2-3

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6 August 2017

page(s)

153-162

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Ceramide in the eukaryotic stress response

6 August 2017

cites work

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7 January 2021

Sphingosine-1-phosphate: signaling inside and out.

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7 January 2021

Ceramide and apoptosis

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7 January 2021

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

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7 January 2021

A possible role of sphingosine in induction of apoptosis by tumor necrosis factor-alpha in human neutrophils

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7 January 2021

Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells

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7 January 2021

Sphingosine generation, cytochrome c release, and activation of caspase-7 in doxorubicin-induced apoptosis of MCF7 breast adenocarcinoma cells.

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7 January 2021

Biosynthesis of sphingolipids: dihydroceramide and not sphinganine is desaturated by cultured cells

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7 January 2021

Physiology and pathophysiology of sphingolipid metabolism and signaling

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7 January 2021

Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification Of the first molecular lesion causing Farber disease

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7 January 2021

Cloning and characterization of the full-length cDNA and genomic sequences encoding murine acid ceramidase

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7 January 2021

Molecular cloning and characterization of a human mitochondrial ceramidase

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7 January 2021

Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase. A novel but highly conserved gene family of neutral/alkaline ceramidases

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7 January 2021

Purification, characterization, molecular cloning, and subcellular distribution of neutral ceramidase of rat kidney

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7 January 2021

Natural ceramide is unable to escape the lysosome, in contrast to a fluorescent analogue

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7 January 2021

Induction of apoptosis and potentiation of ceramide-mediated cytotoxicity by sphingoid bases in human myeloid leukemia cells

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7 January 2021

Sphingosine and its methylated derivative N,N-dimethylsphingosine (DMS) induce apoptosis in a variety of human cancer cell lines

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7 January 2021

Inhibition of sphingolipid induced apoptosis by caspase inhibitors indicates that sphingosine acts in an earlier part of the apoptotic pathway than ceramide

1 reference

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7 January 2021

Coordinate regulation of stress- and mitogen-activated protein kinases in the apoptotic actions of ceramide and sphingosine.

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7 January 2021

Signal transduction by the JNK group of MAP kinases

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7 January 2021

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

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7 January 2021

p38 mitogen-activated protein kinase-dependent and -independent intracellular signal transduction pathways leading to apoptosis in human neutrophils

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7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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7 January 2021

Selectivity of sphingosine-induced apoptosis. Lack of activity of DL-erythyro-dihydrosphingosine

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

The biochemistry of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Role of AKT kinase in sphingosine-induced apoptosis in human hepatoma cells

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https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Expression of alpha-catenin in alpha-catenin-deficient cells increases resistance to sphingosine-induced apoptosis

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https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Mitochondria as the central control point of apoptosis

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7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

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7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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7 January 2021

Suppression of bcl-2 gene expression by sphingosine in the apoptosis of human leukemic HL-60 cells during phorbol ester-induced terminal differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Sphingosine induces apoptosis in androgen-independent human prostatic carcinoma DU-145 cells by suppression of bcl-X(L) gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Bax-dependent apoptosis induced by ceramide in HL-60 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Life-or-death decisions by the Bcl-2 protein family.

1 reference

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7 January 2021

Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis

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7 January 2021

Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress

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7 January 2021

Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

BAD Enables Ceramide to Signal Apoptosis via Ras and Raf-1

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Cross-talk between phosphatidylinositol 3-kinase and sphingomyelinase pathways as a mechanism for cell survival/death decisions

1 reference

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7 January 2021

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

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7 January 2021

Rsk1 mediates a MEK-MAP kinase cell survival signal

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7 January 2021

Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.

1 reference

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7 January 2021

Protein kinase C theta and epsilon promote T-cell survival by a rsk-dependent phosphorylation and inactivation of BAD.

1 reference

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7 January 2021

p90(RSK) blocks bad-mediated cell death via a protein kinase C-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Functions of sphingolipids and sphingolipid breakdown products in cellular regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Effect of chemically well-defined sphingosine and its N-methyl derivatives on protein kinase C and src kinase activities

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Regulation of sphingosine-activated protein kinases: selectivity of activation by sphingoid bases and inhibition by non-esterified fatty acids

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

The signal modulator protein 14-3-3 is a target of sphingosine- or N,N-dimethylsphingosine-dependent kinase in 3T3(A31) cells

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Endogenous substrates of sphingosine-dependent kinases (SDKs) are chaperone proteins: heat shock proteins, glucose-regulated proteins, protein disulfide isomerase, and calreticulin

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

A novel sphingosine-dependent protein kinase (SDK1) specifically phosphorylates certain isoforms of 14-3-3 protein

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Stereoselectivity of induction of the retinoblastoma gene product (pRb) dephosphorylation by D-erythro-sphingosine supports a role for pRb in growth suppression by sphingosine

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Activation of a retinoblastoma-protein-dependent pathway by sphingosine

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Action of Myc in vivo - proliferation and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Cathepsin D targeted by acid sphingomyelinase-derived ceramide

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

1 reference

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7 January 2021

N,N-dimethylsphingosine inhibition of sphingosine kinase and sphingosine 1-phosphate activity in human platelets

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

N,N-Dimethylsphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: modulation of cellular levels of sphingosine 1-phosphate and ceramide.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Protein kinase C and platelet inhibition by D-erythro-sphingosine: comparison with N,N-dimethylsphingosine and commercial preparation

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

A ceramide analogue inhibits T cell proliferative response through inhibition of glycosphingolipid synthesis and enhancement of N,N-dimethylsphingosine synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Simultaneous quantitative determination method for sphingolipid metabolites by liquid chromatography/ionspray ionization tandem mass spectrometry

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7 January 2021

Enzymatic synthesis of N,N-dimethyl-sphingosine: demonstration of the sphingosine: N-methyltransferase in mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Mechanisms of cycloheximide-induced apoptosis in liver cells

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Apoptosis in the skeletal muscle of rats with heart failure is associated with increased serum levels of TNF-alpha and sphingosine

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

A possible role of nuclear ceramide and sphingosine in hepatocyte apoptosis in rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Distinctive inhibitory activity of docosahexaenoic acid against sphingosine-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

Characterization of cytotoxicity induced by sphingolipids in multidrug-resistant leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900336-0

7 January 2021

10.1016/S1388-1981(02)00336-0

Identifiers

DOI

1 reference

6 August 2017

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