(Q35047921)

6 August 2017

title

Inhibition of SIRT2 in merlin/NF2-mutant Schwann cells triggers necrosis (English)

1 reference

6 August 2017

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Alejandra Petrilli

1

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6 August 2017

Marga Bott

series ordinal

2

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6 August 2017

Cristina Fernández-Valle

series ordinal

3

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6 August 2017

language of work or name

English

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publication date

1 December 2013

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6 August 2017

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6 August 2017

volume

4

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6 August 2017

issue

12

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6 August 2017

page(s)

2354-2365

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describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3926832/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Poly(ADP-ribose) polymerase mediates both cell death and ATP decreases in SIRT2 inhibitor AGK2-treated microglial BV2 cells

8 July 2018

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The NAD-dependent deacetylase SIRT2 is required for programmed necrosis

8 July 2018

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8 July 2018

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Histone deacetylase inhibitor AR-42 differentially affects cell-cycle transit in meningeal and meningioma cells, potently inhibiting NF2-deficient meningioma growth

8 July 2018

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Sirtuin 2 (SIRT2) enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via deacetylating forkhead box O3a (Foxo3a) and activating Bim protein

8 July 2018

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8 July 2018

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The role of sirtuin 2 activation by nicotinamide phosphoribosyltransferase in the aberrant proliferation and survival of myeloid leukemia cells

8 July 2018

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8 July 2018

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AR42, a novel histone deacetylase inhibitor, as a potential therapy for vestibular schwannomas and meningiomas

8 July 2018

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8 July 2018

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Schwannomin/merlin promotes Schwann cell elongation and influences myelin segment length

8 July 2018

1 reference

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

1 reference

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8 July 2018

1 reference

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SIRT2 downregulation confers resistance to microtubule inhibitors by prolonging chronic mitotic arrest

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

Structural Insights into Intermediate Steps in the Sir2 Deacetylation Reaction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

Sirtuins: Sir2-related NAD-dependent protein deacetylases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

HDAC6 is a microtubule-associated deacetylase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

Establishment and characterization of a schwannoma cell line from a patient with neurofibromatosis 2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

Signaling pathways regulating dose-dependent dual effects of TNF-α on primary cultured Schwann cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

β-1,4-Galactosyltransferase I involved in Schwann cells proliferation and apoptosis induced by tumor necrosis factor-alpha via the activation of MAP kinases signal pathways.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

Tumor necrosis factor-alpha inhibits Schwann cell proliferation by up-regulating Src-suppressed protein kinase C substrate expression

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

Serum and forskolin cooperate to promote G1 progression in Schwann cells by differentially regulating cyclin D1, cyclin E1, and p27Kip expression.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3926832

25 October 2018

Identifiers

DOI

10.18632/ONCOTARGET.1422

0 references

PMC publication ID

3926832

1 reference

6 August 2017

1 reference