(Q39244903)

English

Histone deacetylase inhibitor AR-42 differentially affects cell-cycle transit in meningeal and meningioma cells, potently inhibiting NF2-deficient meningioma growth

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Histone deacetylase inhibitor AR-42 differentially affects cell-cycle transit in meningeal and meningioma cells, potently inhibiting NF2-deficient meningioma growth (English)

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

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author name string

Sarah S Burns

1

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Elena M Akhmametyeva

2

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Janet L Oblinger

3

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Matthew L Bush

4

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Jie Huang

5

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Volker Senner

6

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Ching-Shih Chen

7

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Abraham Jacob

8

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

D Bradley Welling

9

1 reference

Europe PubMed Central

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10 September 2017

Long-Sheng Chang

10

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Europe PubMed Central

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10 September 2017

language of work or name

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publication date

14 November 2012

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Europe PubMed Central

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10 September 2017

Cancer Research

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Europe PubMed Central

PMC publication ID

10 September 2017

73

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Europe PubMed Central

PMC publication ID

10 September 2017

2

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

792-803

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

describes a project that uses

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1 reference

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Preclinical validation of AR42, a novel histone deacetylase inhibitor, as treatment for vestibular schwannomas

1 reference

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10 September 2017

AR42, a novel histone deacetylase inhibitor, as a potential therapy for vestibular schwannomas and meningiomas

1 reference

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Epidemiology and etiology of meningioma

1 reference

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Degradation of cyclin A is regulated by acetylation.

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NF2/merlin is a novel negative regulator of mTOR complex 1, and activation of mTORC1 is associated with meningioma and schwannoma growth

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Phosphatidylinositol 3-kinase/AKT pathway activation in human vestibular schwannoma

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Anticancer activities of histone deacetylase inhibitors

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Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim.

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Aurora-kinase inhibitors as anticancer agents

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Molecular characterization of human meningiomas by gene expression profiling using high-density oligonucleotide microarrays

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Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse

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Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

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Dual degradation of aurora A and B kinases by the histone deacetylase inhibitor LBH589 induces G2-M arrest and apoptosis of renal cancer cells.

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OSU-HDAC42, a histone deacetylase inhibitor, blocks prostate tumor progression in the transgenic adenocarcinoma of the mouse prostate model

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cDNA microarray analysis of vestibular schwannomas

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12 December 2020

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Molecular biology of vestibular schwannomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/23151902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects

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https://pubmed.ncbi.nlm.nih.gov/23151902

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Identifiers

10.1158/0008-5472.CAN-12-1888

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

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