(Q35052092)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Accelerated in vivo epidermal telomere loss in Werner syndrome (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

author name string

Naoshi Ishikawa

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Ken-Ichi Nakamura

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Naotaka Izumiyama-Shimomura

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Akio Ishii

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Makoto Goto

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Yuichi Ishikawa

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Reimi Asaka

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Masaaki Matsuura

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Atsushi Hatamochi

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Mie Kuroiwa

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Kaiyo Takubo

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

publication date

1 April 2011

1 reference

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6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

volume

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

page(s)

417-429

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression

6 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

How shelterin protects mammalian telomeres

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Flap endonuclease 1 contributes to telomere stability

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Human premature aging, DNA repair and RecQ helicases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Telomere dysfunction as a cause of genomic instability in Werner syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Longitudinal data on telomere length in leukocytes from newborn baboons support a marked drop in stem cell turnover around 1 year of age.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

The serial cultivation of human diploid cell strains

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

The rate of telomere sequence loss in human leukocytes varies with age.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Extension of life-span by introduction of telomerase into normal human cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein-Barr virus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Telomere length regulation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Positional cloning of the Werner's syndrome gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Hypermutable ligation of plasmid DNA ends in cells from patients with Werner syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

The gene responsible for Werner syndrome may be a cell division "counting" gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

DNA damage and repair in telomeres: relation to aging

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Cytogenetics of Werner's syndrome cultured skin fibroblasts: variegated translocation mosaicism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Telomeres shorten during ageing of human fibroblasts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Telomere loss: mitotic clock or genetic time bomb?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Telomere length predicts replicative capacity of human fibroblasts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Genetic syndromes in man with potential relevance to the pathobiology of aging

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Telomeric DNA length in cerebral gray and white matter is associated with longevity in individuals aged 70 years or older

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Normal telomere erosion rates at the single cell level in Werner syndrome fibroblast cells.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Comparative analysis of telomere lengths and erosion with age in human epidermis and lingual epithelium.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Telometric: a tool providing simplified, reproducible measurements of telomeric DNA from constant field agarose gels.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Telomere states and cell fates

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Telomerase and cellular lifespan: ending the debate?

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

A genetic analysis of the Werner syndrome region on human chromosome 8p.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117457

Comparison of chromosome telomere integrity in multiple tissues from subjects at different ages

25 October 2018

1 reference

12 December 2020

Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

1 reference

12 December 2020

Telomere lengths are characteristic in each human individual

1 reference

12 December 2020

Telomere shortening with aging in human esophageal mucosa

1 reference

12 December 2020

Telomere shortening with aging in human liver

1 reference

12 December 2020

In vivo loss of telomeric repeats with age in humans

1 reference

12 December 2020

1 reference

12 December 2020

Regulation of c-fos expression in senescing Werner syndrome fibroblasts differs from that observed in senescing fibroblasts from normal donors

1 reference

12 December 2020

Mutations in dyskeratosis congenita: their impact on telomere length and the diversity of clinical presentation

1 reference

12 December 2020

Identifiers

DOI

10.18632/AGING.100315

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732564%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

21732564

1 reference