(Q35054594)

6 August 2017

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title

Functional tuning of nucleic acids by chemical modifications: tailored oligonucleotides as drugs, devices, and diagnostics (English)

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6 August 2017

Oliver Thum

3

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author name string

Sandeep Verma

series ordinal

1

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PubMed ID

12552531

6 August 2017

Stefan Jäger

series ordinal

2

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PubMed ID

12552531

6 August 2017

Michael Famulok

series ordinal

4

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6 August 2017

1 January 2003

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6 August 2017

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6 August 2017

3

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6 August 2017

1

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6 August 2017

51-60

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Ribozyme structures and mechanisms

6 August 2017

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Nucleic acid aptamers-from selection in vitro to applications in vivo

21 January 2018

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MODIFIED OLIGONUCLEOTIDES: Synthesis and Strategy for Users

21 January 2018

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Backbone modification of nucleic acids: synthesis, structure and therapeutic applications.

21 January 2018

1 reference

Towards the selection of phosphorothioate aptamers optimizing in vitro selection steps with phosphorothioate nucleotides.

21 January 2018

1 reference

Novel combinatorial selection of phosphorothioate oligonucleotide aptamers

21 January 2018

1 reference

In vitro selection of phosphorothiolated aptamers

21 January 2018

1 reference

Synthetic oligonucleotides as RNA mimetics: 2'-modified Rnas and N3'-->P5' phosphoramidates

21 January 2018

1 reference

RNA and N3'-->P5' kissing aptamers targeted to the trans-activation responsive (TAR) RNA of the human immunodeficiency virus-1.

21 January 2018

1 reference

2'-Fluoro modified nucleic acids: polymerase-directed synthesis, properties and stability to analysis by matrix-assisted laser desorption/ionization mass spectrometry

21 January 2018

1 reference

Potent 2'-amino-, and 2'-fluoro-2'-deoxyribonucleotide RNA inhibitors of keratinocyte growth factor

21 January 2018

1 reference

Modified RNA sequence pools for in vitro selection

21 January 2018

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High-affinity and specific recognition of human thyroid stimulating hormone (hTSH) by in vitro-selected 2'-amino-modified RNA.

21 January 2018

1 reference

Differential minor groove interactions between DNA polymerase and sugar backbone of primer and template strands

21 January 2018

1 reference

A method to select chemically modified aptamers directly

21 January 2018

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Mechanistic aspects of enzymatic catalysis: lessons from comparison of RNA and protein enzymes

21 January 2018

1 reference

Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics

21 January 2018

1 reference

Peptide bond formation by in vitro selected ribozymes

21 January 2018

1 reference

RNA-catalyzed RNA ligation on an external RNA template

21 January 2018

1 reference

An in vitro evolved precursor tRNA with aminoacylation activity

21 January 2018

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Ribozyme-catalyzed tRNA aminoacylation.

21 January 2018

1 reference

A novel ribozyme with ester transferase activity

21 January 2018

1 reference

A small catalytic RNA motif with Diels-Alderase activity.

21 January 2018

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Novel RNA catalysts for the Michael reaction

21 January 2018

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Selection of RNA amide synthases

21 January 2018

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In vitro selection of a ligase ribozyme carrying alkylamino groups in the side chains

21 January 2018

1 reference

RNA cleavage by a DNA enzyme with extended chemical functionality

21 January 2018

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A general purpose RNA-cleaving DNA enzyme

21 January 2018

1 reference

Bridging the gap between proteins and nucleic acids: a metal-independent RNAseA mimic with two protein-like functionalities

21 January 2018

1 reference

Quantitative analysis of receptors for adenosine nucleotides obtained via in vitro selection from a library incorporating a cationic nucleotide analog

21 January 2018

1 reference

Enhancing the catalytic repertoire of nucleic acids: a systematic study of linker length and rigidity

21 January 2018

1 reference

In vitro selection of RNA aptamers carrying multiple biotin groups in the side chains

21 January 2018

1 reference

Enhancing the catalytic repertoire of nucleic acids. II. Simultaneous incorporation of amino and imidazolyl functionalities by two modified triphosphates during PCR.

21 January 2018

1 reference

Progress towards single-molecule sequencing: enzymatic synthesis of nucleotide-specifically labeled DNA.

21 January 2018

1 reference

Functionalized nucleoside 5'-triphosphates for in vitro selection of new catalytic ribonucleic acids

21 January 2018

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The large fragment of Escherichia coli DNA polymerase I can synthesize DNA exclusively from fluorescently labeled nucleotides.

21 January 2018

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Long-range photoinduced electron transfer through a DNA helix

21 January 2018

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Oxidative DNA damage through long-range electron transfer

21 January 2018

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Dynamics of photoinduced charge transfer and hole transport in synthetic DNA hairpins

21 January 2018

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Long-range charge transfer in DNA: transient structural distortions control the distance dependence

21 January 2018

1 reference

Probing DNA charge transport with metallointercalators

21 January 2018

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Femtosecond direct observation of charge transfer between bases in DNA

21 January 2018

1 reference

Molecular computation by DNA hairpin formation.

21 January 2018

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Using DNA to solve the Bounded Post Correspondence Problem

21 January 2018

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Molecular computation: RNA solutions to chess problems

21 January 2018

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The past, present and future of molecular computing.

21 January 2018

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21 January 2018

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The complexities of DNA computation

21 January 2018

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From DNA biosensors to gene chips

21 January 2018

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Biomaterials integrated with electronic elements: en route to bioelectronics

21 January 2018

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Research and development in biosensors

21 January 2018

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Allosterically controllable ribozymes with biosensor functions

21 January 2018

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Oligonucleotide aptamers that recognize small molecules

21 January 2018

1 reference

A fiber-optic microarray biosensor using aptamers as receptors

21 January 2018

1 reference

In vitro evolution of a ribozyme that contains 5-bromouridine

21 January 2018

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Detection of point mutations in DNA by PNA-based quartz-crystal biosensor

21 January 2018

1 reference

In vitro evolution of new ribozymes with polynucleotide kinase activity

21 January 2018

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RNA-catalysed carbon–carbon bond formation

21 January 2018

1 reference

Debating controversies can enhance creativity

21 January 2018

1 reference

Synthesis and stability of oligodeoxynucleotides containing C8-labeled 2'-deoxyadenosine: novel redox nucleobase probes for DNA-mediated charge-transfer studies

21 January 2018

1 reference

2'-Fluoro- and 2'-amino-2'-deoxynucleoside 5'-triphosphates as substrates for T7 RNA polymerase

21 January 2018

1 reference

Toward an RNaseA mimic: A DNAzyme with imidazoles and cationic amines

21 January 2018

1 reference

Long-distance charge transport in DNA: the hopping mechanism

21 January 2018

1 reference

A DNA computing readout operation based on structure-specific cleavage

21 January 2018

1 reference

In vitro selection of DNA aptamers to anthrax spores with electrochemiluminescence detection

21 January 2018

1 reference

Bioassay of bile acids using an enzyme-linked DNA aptamer

21 January 2018

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In vitro selection of signaling aptamers

21 January 2018

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Adapting selected nucleic acid ligands (aptamers) to biosensors

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/TCR.10047

1 reference

6 August 2017

1 reference

PubMed ID

12552531